Peanut Oil + Irinotecan Hydrochloride
We found no known interaction between Peanut Oil and Irinotecan Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Irinotecan Hydrochloride states a food rule worth keeping to.
Peanut Oil and Irinotecan Hydrochloride
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Irinotecan Hydrochloride and Peanut Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Peanut Oil at all — not against Irinotecan Hydrochloride, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Peanut Oil safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Irinotecan Hydrochloride Products Have a Food Rule — Peanut Oil Should Not Break It
At least one FDA label for a product containing Irinotecan Hydrochloride says to take it on an empty stomach. Most supplements — Peanut Oil included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Irinotecan Hydrochloride on its own and move Peanut Oil to a meal later in the day.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Irinotecan Hydrochloride products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Antiemetic agents should be given on the day of treatment, starting at least 30 minutes before administration of CAMPTOSAR.
From the Dosage and Administration section of the FDA label we read for Irinotecan Hydrochloride — where that label names a specific product, the instruction is that product's. See the Irinotecan Hydrochloride drug page ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Irinotecan Hydrochloride
This page covers Peanut Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Irinotecan Hydrochloride page lists 135 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Apple (major), Grapefruit (major), St. John's Wort (major), Sweet Orange (major) and Acacia Rigidula (moderate).
By severity: 4 major · 100 moderate · 31 minor.
From our pharmacist’s overview on the Irinotecan Hydrochloride page
“Irinotecan hydrochloride is chemotherapy, most often used against colorectal cancer, so the 135 supplements and foods on this page call for genuine care rather than a shrug. Four entries rate major, and St.”
Reviewed by 2 · Jul 18, 2026
Where Peanut Oil and Irinotecan Hydrochloride Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,336 of 1,452 supplements looked up here in the last 7 days
#1,424 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Peanut Oil reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Peanut Oil and Irinotecan Hydrochloride records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Peanut Oil
What is Peanut Oil?
- Cooking and frying
- Skin moisturizing and massage
- Carrier oil for other ingredients
- Earwax softening (folk use)
- Dry or chapped skin
Peanut oil is a food-grade oil pressed from peanuts, used mainly for cooking and as a skin or massage oil. It is generally considered safe as a food, but people with peanut allergy should be cautious, especially with crude (less-refined) oils, and there is little strong evidence for medicinal benefits.
Arachis hypogaea · Fabaceae · Oil pressed from the seeds (peanuts) · Cooking oil, topical/massage oil, ingredient in skin and hair products, carrier oil, some injectable medication formulations
An interaction check asks whether these two react with each other — it does not ask whether Peanut Oil is a good idea for someone in your situation. Here is what our Peanut Oil record says about it on its own.
Peanut Oil: dosing
There is no established medicinal dose for peanut oil. As a cooking oil, it is used in normal culinary amounts, like any other vegetable oil.If you are using a product that contains peanut oil for skin care or another purpose, follow the directions on the label.
From our Peanut Oil monograph — the full record covers uses, side effects and every documented interaction.
About Irinotecan Lipid Complex Injection
What Is Irinotecan Lipid Complex Injection Used For?
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Irinotecan lipid complex is used in combination with other medications to treat pancreatic cancer that has spread to other parts of the body that has worsened after treatment with other chemotherapy medications. Irinotecan lipid complex is in a class of antineoplastic medications called topoisomerase I inhibitors. It works by stopping the growth of cancer cells.
Other Drugs & Peanut Oil
Browse every other medication we’ve checked against Peanut Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Peanut Oil against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Peanut Oil list.
Peanut Oil References
The 1 references that drive our Peanut Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Akhtar S, Khalid N, Ahmed I, Shahzad A, Suleria HA. Physicochemical characteristics, functional properties, and nutritional benefits of peanut oil: a review. Crit Rev Food Sci Nutr. 2014;54(12):1562-75. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Peanut Oil and Irinotecan Hydrochloride Together: Common Questions
Is it safe to take Peanut Oil with Irinotecan Hydrochloride?
Should I take Peanut Oil and Irinotecan Hydrochloride at the same time of day?
Does Irinotecan Hydrochloride interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.