Drug & supplement interaction

Pellitory + Fosinopril, Hydrochlorothiazide

Fosinopril, Hydrochlorothiazide brand name: Monopril HCT.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Pellitory and Fosinopril, Hydrochlorothiazide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Pellitory and Fosinopril, Hydrochlorothiazide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Fosinopril, Hydrochlorothiazide and Pellitory in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Pellitory at all — not against Fosinopril, Hydrochlorothiazide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pellitory safety at a glance

Pellitory overall Use caution Limited safety data exist, and it may cause mouth irritation or allergic reactions.
Pregnancy Avoid Not enough safety information is available, so it is best avoided.
Breastfeeding Avoid There is no reliable safety data during breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Fosinopril, Hydrochlorothiazide and Pellitory? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Fosinopril, Hydrochlorothiazide’s Own FDA Label Lists

This is not an interaction — none of it involves Pellitory. These are the most notable effects listed in the ADVERSE REACTIONS section of Fosinopril, Hydrochlorothiazide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Raised blood pressure Worth acting on
  • A higher chance of infection Worth acting on
  • Cough
  • Muscle pain
  • Tiredness
  • Dizziness
  • Headache

From the ADVERSE REACTIONS section of the FDA label for Fosinopril, Hydrochlorothiazide. Read the label on DailyMed › Pellitory’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Pellitory side to compare — that is a limit of the record, not a statement that Pellitory has no side effects.

Everything else you take

See Every Supplement That Interacts With Fosinopril, Hydrochlorothiazide

This page covers Pellitory only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Fosinopril, Hydrochlorothiazide page lists 238 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Dolomite (major).

By severity: 11 major · 200 moderate · 27 minor.

From our pharmacist’s overview on the Fosinopril, Hydrochlorothiazide page

“Monopril HCT combines two blood pressure medicines, the ACE inhibitor fosinopril and the water pill hydrochlorothiazide, which is why I read its supplement list with genuine wariness rather than a shrug. Eleven of the 238 ingredients on file carry a major rating and deserve your attention first, while most of the 200 rated moderate eit…”

Reviewed by 2 · Jul 18, 2026

Open the Fosinopril, Hydrochlorothiazide interaction page

One more smart check

Taking Pellitory as Part of a Dietary Supplement Product? Check It for Interactions

We hold 36 real supplement products containing Pellitory, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pellitory. Even though Pellitory itself has no known interaction with Fosinopril, Hydrochlorothiazide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Pellitory and Fosinopril, Hydrochlorothiazide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pellitory
Steady interest

#1,029 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Fosinopril, Hydrochlorothiazide
Steady interest

#1,458 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pellitory reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Pellitory and Fosinopril, Hydrochlorothiazide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pellitory

What is Pellitory?

  • Toothache and oral discomfort
  • Increasing saliva flow
  • Sluggish digestion
  • Traditional tonic in some folk medicine systems

Pellitory (often Anacyclus pyrethrum, the root traditionally called 'pellitory of Spain') is an herb chiefly known in folk and traditional medicine for numbing toothache and stimulating saliva. Human evidence for its benefits is very limited, so it should be viewed as a traditional remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Anacyclus pyrethrum · Asteraceae · Root · Powder, root extract, tinctures, tooth powders and mouthwashes

An interaction check asks whether these two react with each other — it does not ask whether Pellitory is a good idea for someone in your situation. Here is what our Pellitory record says about it on its own.

Pellitory: dosing

There is no well-established, standardized dose for pellitory, and product strengths vary widely.

From our Pellitory monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pellitory monograph & all interactions
Keep checking

Other Drugs & Pellitory

Browse every other medication we’ve checked against Pellitory — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Pellitory References

The 1 references that drive our Pellitory monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pellitory and Fosinopril, Hydrochlorothiazide Together: Common Questions

Is it safe to take Pellitory with Fosinopril, Hydrochlorothiazide?
We do not list a known interaction between Pellitory and Fosinopril, Hydrochlorothiazide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Fosinopril, Hydrochlorothiazide interact with any supplements?
Yes. Fosinopril, Hydrochlorothiazide has documented interactions with 238 supplements in our database — Pellitory is not one of them. The Fosinopril, Hydrochlorothiazide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Fosinopril, Hydrochlorothiazide and Pellitory?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.