Drug & supplement interaction

Phaseolus Vulgaris + Atovaquone

Atovaquone brand name: Mepron.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Phaseolus Vulgaris and Atovaquone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Atovaquone states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share

Facebook Post Reddit Email

On this page

Interaction report

Phaseolus Vulgaris and Atovaquone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Atovaquone and Phaseolus Vulgaris in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Phaseolus Vulgaris safety at a glance

Phaseolus Vulgaris overall Use caution Beans are a safe food when cooked, but concentrated extracts have less safety data and may cause digestive upset.

Pregnancy Use caution Beans as food are fine, but concentrated extracts are not well studied in pregnancy, so avoid them unless your doctor approves.

Breastfeeding Use caution Beans as food are fine, but there is little data on concentrated extracts during breastfeeding, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Atovaquone and Phaseolus Vulgaris? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Atovaquone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Atovaquone is filed under a single classification — oral drugs. Phaseolus Vulgaris has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Atovaquone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Phaseolus Vulgaris Does Interact With Other Medications

Phaseolus Vulgaris has 86 moderate known drug interactions in our database — Atovaquone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Atovaquone)

Taking anything else?

Check Another of Your Medications Against Phaseolus Vulgaris

Covers the 2,830 medications we’ve checked against Phaseolus Vulgaris. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Phaseolus Vulgaris and Atovaquone May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

A severe allergic reaction / An allergic reaction Worth acting on Additional detail

Phaseolus Vulgaris

“Orally, Phaseolus vulgaris extract seems to be well tolerated.

Most Common Adverse Effects:

Orally: Constipation, diarrhea, flatulence, nausea, stomach pain, and vomiting.

Serious Adverse Effects (Rare):

Orally: Hypersensitivity reactions, including anaphylaxis, in sensitive individuals.”

Phaseolus Vulgaris · Natural Medicines adverse-effect record, reported in constipation.

Atovaquone

Listed in the ADVERSE REACTIONS section of the FDA label for Atovaquone. Read the label on DailyMed ›
Itching / A skin rash Additional detail
Phaseolus Vulgaris
“Topically, Phaseolus vulgaris may cause contact dermatitis in sensitive individuals. A case of occupational contact dermatitis characterized by pruritus, erythema, eczema, and dyspnea has been reported for a 41-year-old farmer who handled the green parts of Phaseolus vulgaris.”

Phaseolus Vulgaris · Natural Medicines adverse-effect record, reported in dermatitis.
1 source cited

29920. Spiewak R, Dutkiewicz J. Occupational contact dermatitis to Phaseolus vulgaris in a farmer - a case report. Ann Agric Environ Med 2000;7(1):55-9.
Atovaquone

Listed in the ADVERSE REACTIONS section of the FDA label for Atovaquone. Read the label on DailyMed ›
Diarrhea / Vomiting / Nausea Additional detail
Phaseolus Vulgaris
“Orally, an extract of the Phaseolus vulgaris variety white kidney bean, as well as alpha-amylase inhibitors isolated from Phaseolus vulgaris, might cause nausea, vomiting, diarrhea, flatulence, constipation, satiety, and stomach pains. Also, white kidney bean extract, taken orally along with carob gum, may cause constipation, flatulence, soft stools, and reduced levels of vitamin B12 and folic acid.”

Phaseolus Vulgaris · Natural Medicines adverse-effect record, reported in constipation.
6 sources cited

11265. FDA Center for Food Safety and Nutrition. What are some of the questionable weight loss products? http://www.cfsan.fda.gov/~dms/qa-nut4.html. (Accessed 20 December 2003).

18223. Onakpoya I, Aldaas S, Terry R, Ernst E. The efficacy of Phaseolus vulgaris as a weight-loss supplement: a systematic review and meta-analysis of randomised clinical trials. Br J Nutr 2011;106:196-202.

29925. Boivin M, Flourie B, Rizza RA, Go VL, DiMagno EP. Gastrointestinal and metabolic effects of amylase inhibition in diabetics. Gastroenterology. 1988;94(2):387-94. PubMed

104874. Jalal SM, Alsultan AA, Alotaibi HH, Mary E, Alabdullatif AAI. Effect of Phaseolus vulgaris on urinary biochemical parameters among patients with kidney stones in Saudi Arabia. Nutrients. 2020 Oct 30;12(11):3346. PubMed

10633. Birketvedt GS, Travis A, Langbakk B, Florholmen JR. Dietary supplementation with bean extract improves lipid profile in overweight and obese subjects. Nutrition 2002;18:729-33.. PubMed

29916. Rodhouse JC, Haugh CA, Roberts D, Gilbert RJ. Red kidney bean poisoning in the UK: an analysis of 50 suspected incidents between 1976 and 1989. Epidemiol Infect 1990;105(3):485-91. PubMed
Atovaquone

Listed in the ADVERSE REACTIONS section of the FDA label for Atovaquone. Read the label on DailyMed ›

Reported for Phaseolus Vulgaris but not commonly for Atovaquone: constipation, stomach pain, bloating or gas and shortness of breath.

Effects for Atovaquone come from the ADVERSE REACTIONS section of its FDA label; effects for Phaseolus Vulgaris come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Atovaquone Products Have a Food Rule — Phaseolus Vulgaris Should Not Break It

At least one FDA label for a product containing Atovaquone says to take it with food. If you take Phaseolus Vulgaris on an empty stomach out of habit, keep them separate — and take Atovaquone with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Atovaquone products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

jirovecii Pneumonia The recommended oral dosage is 1,500 mg (10 mL) once daily administered with food.

From the Dosage and Administration section of the FDA label we read for Atovaquone — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Atovaquone

This page covers Phaseolus Vulgaris only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Atovaquone page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Atovaquone page

“Atovaquone (Mepron) is usually taken to prevent or treat Pneumocystis pneumonia, often when the immune system is already weakened, so a dose that never absorbs is a treatment failure, not a nuisance. All 17 supplement interactions on file act in the gut, changing how much of the drug reaches the blood, and I read this list as one deser…”

Reviewed by 2 · Jul 18, 2026

Open the Atovaquone interaction page

How much people look this up

Where Phaseolus Vulgaris and Atovaquone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Phaseolus Vulgaris

Steady interest

#1,177 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Atovaquone

Top half

#1,069 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Phaseolus Vulgaris reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Phaseolus Vulgaris and Atovaquone records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Phaseolus Vulgaris

What is Phaseolus Vulgaris?

Weight management
Carbohydrate ('starch') blocking
Blood sugar support
General nutrition and fiber

Phaseolus vulgaris, the common bean, is widely eaten as food, and a concentrated white bean extract is marketed as a 'carb blocker' for weight loss. Some small studies suggest it may modestly reduce starch digestion, but the evidence for meaningful weight loss is limited and mixed. Talk to your pharmacist or doctor before using it as a supplement, and remember beans must be cooked thoroughly because raw or undercooked beans can be toxic.

Phaseolus vulgaris · Fabaceae · Seeds (beans), bean pods, and extracts of the seed · Capsules, tablets, powder, standardized white bean extract ('Phase 2'), whole beans as food

An interaction check asks whether these two react with each other — it does not ask whether Phaseolus Vulgaris is a good idea for someone in your situation. Here is what our Phaseolus Vulgaris record says about it on its own.

Phaseolus Vulgaris: dosing

There is no official standardized dose of Phaseolus vulgaris extract for weight loss or any other use. Products vary widely in strength and in how they are standardized (for example, by amount of alpha-amylase inhibitor activity).The safest approach is to follow the directions on the product label and not exceed them. Extract is usually taken shortly before starchy meals. Beans as food can simply be enjoyed as part of a balanced diet.

From our Phaseolus Vulgaris monograph — the full record covers uses, side effects and every documented interaction.

Read the full Phaseolus Vulgaris monograph & all interactions

Medication

About Atovaquone

What Is Atovaquone Used For?

Brand name: Mepron

Atovaquone oral suspension — available as the brand Mepron and as generic products — is used in adults and adolescents aged 13 and older who cannot tolerate trimethoprim-sulfamethoxazole (TMP-SMX), the usual first-choice treatment.

It is approved for two purposes: preventing PCP in people at high risk, and treating mild-to-moderate PCP in those who already have it. It has not been studied for severe PCP or for people whose PCP is not responding to TMP-SMX, so it is not used in those situations.

See full Atovaquone drug information

Keep checking

Other Drugs & Phaseolus Vulgaris

Browse every other medication we’ve checked against Phaseolus Vulgaris — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

86Moderate

0Minor

2,743No known interaction

86 Moderate 2,743 No interaction

Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Phaseolus Vulgaris page.

No interaction 2,743 drugs checked — show the list

We also checked Phaseolus Vulgaris against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Phaseolus Vulgaris list.

See the full Phaseolus Vulgaris interactions page

See every supplement checked against Atovaquone, ranked by severity

Evidence & sources

Phaseolus Vulgaris References

The 11 references that drive our Phaseolus Vulgaris monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Birketvedt GS, Travis A, Langbakk B, Florholmen JR. Dietary supplementation with bean extract improves lipid profile in overweight and obese subjects. Nutrition 2002;18:729-33.. PubMed
FDA Center for Food Safety and Nutrition. What are some of the questionable weight loss products? http://www.cfsan.fda.gov/~dms/qa-nut4.html. (Accessed 20 December 2003).
Onakpoya I, Aldaas S, Terry R, Ernst E. The efficacy of Phaseolus vulgaris as a weight-loss supplement: a systematic review and meta-analysis of randomised clinical trials. Br J Nutr 2011;106:196-202.
Rodhouse JC, Haugh CA, Roberts D, Gilbert RJ. Red kidney bean poisoning in the UK: an analysis of 50 suspected incidents between 1976 and 1989. Epidemiol Infect 1990;105(3):485-91. PubMed
Spiewak R, Dutkiewicz J. Occupational contact dermatitis to Phaseolus vulgaris in a farmer - a case report. Ann Agric Environ Med 2000;7(1):55-9.
Tjokroprawiro A, Pikir BS, Budhiarta AA, et al. Metabolic effects of onion and green beans on diabetic patients. Tohoku J Exp Med 1983;141 Suppl:671-6. PubMed
Boivin M, Flourie B, Rizza RA, Go VL, DiMagno EP. Gastrointestinal and metabolic effects of amylase inhibition in diabetics. Gastroenterology. 1988;94(2):387-94. PubMed
Ionescu-Tirgoviste, C., Popa, E., Mirodon, Z., Simionescu, M., and Mincu, I. [The effect of a plant mixture on the metabolic equilibrium in patients with type-2 diabetes mellitus]. Rev.Med Interna Neurol.Psihiatr.Neurochir.Dermatovenerol.Med Interna 1989
He S, Simpson BK, Sun H, et al. Phaseolus vulgaris lectins: a systematic review of characteristics and health implications. Crit Rev Food Sci Nutr 2015 Oct 19:0. PubMed
Jalal SM, Alsultan AA, Alotaibi HH, Mary E, Alabdullatif AAI. Effect of Phaseolus vulgaris on urinary biochemical parameters among patients with kidney stones in Saudi Arabia. Nutrients. 2020 Oct 30;12(11):3346. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Phaseolus Vulgaris and Atovaquone Together: Common Questions

Is it safe to take Phaseolus Vulgaris with Atovaquone?

We do not list a known interaction between Phaseolus Vulgaris and Atovaquone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Phaseolus Vulgaris and Atovaquone have any of the same side effects?

Yes — our sources link each of them separately to 7 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Should I take Phaseolus Vulgaris and Atovaquone at the same time of day?

At least one FDA label for a product containing Atovaquone says to take it with food. If you take Phaseolus Vulgaris on an empty stomach out of habit, keep them separate and take Atovaquone with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Atovaquone products can differ — so check the directions on your own box. This is about absorption, not an interaction.

How was the Phaseolus Vulgaris and Atovaquone combination checked?

Interactions in our licensed database are recorded against drug classes. Atovaquone is filed under 1 classification, and Phaseolus Vulgaris has documented interactions with 1 drug class — none of Atovaquone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Phaseolus Vulgaris interact with any other medications?

Yes. Phaseolus Vulgaris has 86 documented drug interactions in our database — Atovaquone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Atovaquone interact with any supplements?

Yes. Atovaquone has documented interactions with 17 supplements in our database — Phaseolus Vulgaris is not one of them. The Atovaquone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Phaseolus Vulgaris monograph Uses, safety profile, and every drug interaction in one place Atovaquone drug information The full plain-English guide to this medication Atovaquone supplement interactions Every supplement checked against Atovaquone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 11 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Atovaquone and Phaseolus Vulgaris?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.