Prolotherapy + Elotuzumab
Elotuzumab brand name: Empliciti.
We found no known interaction between Prolotherapy and Elotuzumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Prolotherapy and Elotuzumab
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Elotuzumab and Prolotherapy in our sources. This does not guarantee that the combination is completely free of risk — research on Prolotherapy alongside specific medications may be limited.
Worth understanding: our licensed dataset holds no drug-interaction record for Prolotherapy at all — not against Elotuzumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
Prolotherapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Prolotherapy safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Elotuzumab
This page covers Prolotherapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Elotuzumab page lists 38 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Ashwagandha (moderate) and Black Cohosh (moderate).
By severity: 3 major · 35 moderate.
From our pharmacist’s overview on the Elotuzumab page
“Elotuzumab (Empliciti) is an infusion for multiple myeloma, and every one of the 38 supplement interactions on file for it comes down to the same organ: the liver. Each ingredient here can stress or injure the liver on its own, and stacking that risk on top of cancer treatment deserves genuine care.”
Reviewed by 2 · Jul 18, 2026
Where Prolotherapy and Elotuzumab Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,266 of 1,452 supplements looked up here in the last 7 days
#100 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Prolotherapy is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Prolotherapy reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Prolotherapy and Elotuzumab records this page draws on were last updated June 20, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Prolotherapy
What is Prolotherapy?
- Chronic low back pain
- Knee osteoarthritis
- Tendon and ligament pain
- Joint instability
- Tennis elbow and other tendinopathies
Prolotherapy is not a dietary supplement or herb; it is an injection procedure in which an irritant solution (usually dextrose) is injected near painful joints, tendons, or ligaments to encourage a healing response. The evidence is mixed and generally low-to-moderate quality, with some studies showing modest pain relief for conditions like knee osteoarthritis and chronic low back pain. It should only be done by a trained, licensed clinician, so talk with your doctor before considering it.
Not applicable (a medical injection procedure) · Injected solution, most often dextrose (sugar water) mixed with a local anesthetic
An interaction check asks whether these two react with each other — it does not ask whether Prolotherapy is a good idea for someone in your situation. Here is what our Prolotherapy record says about it on its own.
Prolotherapy: dosing
There is no single standard dose or protocol for prolotherapy. The type of solution (most often dextrose), the concentration, the amount injected, the number of injection sites, and how many sessions are needed all vary based on the clinician, the body area, and the condition being treated.Treatment is usually given as a series of sessions spaced a few weeks apart.
From our Prolotherapy monograph — the full record covers uses, side effects and every documented interaction.
About Elotuzumab Injection
What Is Elotuzumab Injection Used For?
Brand name: Empliciti
Empliciti is used to treat multiple myeloma (a cancer of plasma cells in the bone marrow) in adults who have already tried other treatments. It is always given as part of a combination regimen — never alone.
Empliciti combined with lenalidomide and dexamethasone is used in adults who have received one to three prior therapies. Empliciti combined with pomalidomide and dexamethasone is used in adults who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor.
Most-Reported Side Effects for Elotuzumab
From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Prolotherapy
Browse every other medication we’ve checked against Prolotherapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Prolotherapy against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Ivermectin ›
- Aspirin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Tadalafil ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Abemaciclib ›
- Ibuprofen ›
- Methamphetamine ›
- Semaglutide ›
- Sumatriptan ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Bupropion ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Acyclovir ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Lamotrigine ›
- Fluoxetine ›
- Amphetamine ›
- Gabapentin ›
- Pregabalin ›
- Acetaminophen, Codeine ›
- Azithromycin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Quetiapine ›
- Methylene Blue ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Naproxen ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Prolotherapy list.
Prolotherapy References
The 1 sources that drive our Prolotherapy monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Prolotherapy is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Pain Management — NIH NCCIH Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Having Prolotherapy While Taking Elotuzumab: Common Questions
Is it safe to have Prolotherapy while taking Elotuzumab?
Does Elotuzumab interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Elotuzumab and Prolotherapy?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.