Drug & supplement interaction

Quebracho Blanco + Lioresal

Lioresal brand name: Lioresal Injection.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Quebracho Blanco and Lioresal in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Quebracho Blanco and Lioresal

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lioresal and Quebracho Blanco in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Quebracho Blanco at all — not against Lioresal, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Quebracho Blanco safety at a glance

Quebracho Blanco overall Use caution Limited human safety data and the bark contains active alkaloids, so use cautiously.
Pregnancy Avoid Not enough safety information; avoid use during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lioresal and Quebracho Blanco? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Quebracho Blanco and Lioresal May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Sweating Additional detail

    Quebracho Blanco

    “Orally, quebracho blanco seems to be well tolerated. However, a thorough evaluation of safety outcomes has not been conducted. Some people who take quebracho blanco bark may experience salivation, headache, outbreaks of sweating, vertigo, stupor, and drowsiness. In large doses, it can cause nausea and vomiting (18).”

    Quebracho Blanco · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Lioresal

    Listed in the ADVERSE REACTIONS section of the FDA label for Lioresal. Read the label on DailyMed ›

  • Drowsiness / Dizziness / Headache Additional detail

    Quebracho Blanco

    “Orally, quebracho blanco bark may cause headache, vertigo, stupor, and drowsiness (18).”

    Quebracho Blanco · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Lioresal

    Listed in the ADVERSE REACTIONS section of the FDA label for Lioresal. Read the label on DailyMed ›

  • Vomiting / Nausea Additional detail

    Quebracho Blanco

    “Orally, quebracho blanco bark may cause salivation. In large doses, it can cause nausea and vomiting (18).”

    Quebracho Blanco · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Lioresal

    Listed in the ADVERSE REACTIONS section of the FDA label for Lioresal. Read the label on DailyMed ›

Effects for Lioresal come from the ADVERSE REACTIONS section of its FDA label; effects for Quebracho Blanco come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Quebracho Blanco or Lioresal

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Quebracho Blanco or Lioresal, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Lioresal

This page covers Quebracho Blanco only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lioresal page lists 10 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Procaine (major), Biofeedback (moderate), Dendrobium (moderate), Ginkgo (moderate) and Lithium (moderate).

By severity: 1 major · 9 moderate.

From our pharmacist’s overview on the Lioresal page

“Lioresal is baclofen, a muscle relaxant prescribed for spasticity, and I would treat its supplement list with genuine care. Of the ten ingredients on file, six, including everyday picks like melatonin and ginkgo, may lower the seizure threshold, an added worry with a drug whose abrupt changes can already provoke seizures.”

Reviewed by 2 · Jul 18, 2026

Open the Lioresal interaction page

How much people look this up

Where Quebracho Blanco and Lioresal Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Quebracho Blanco
Top half

#665 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lioresal
Top half

#957 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Quebracho Blanco reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Quebracho Blanco and Lioresal records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Quebracho Blanco

What is Quebracho Blanco?

  • Coughs and breathing problems
  • Asthma and bronchitis symptoms
  • Altitude or shortness of breath
  • Erectile dysfunction (traditional)
  • Fever and digestive upset

Quebracho Blanco is the bark of a South American tree traditionally used for breathing problems and coughs, but high-quality human studies are lacking. It contains alkaloids that may affect blood vessels and breathing, so safety is not well established—talk to your pharmacist or doctor before using it.

Aspidosperma quebracho-blanco · Apocynaceae · Bark · Tincture, liquid extract, dried bark for tea, capsules

An interaction check asks whether these two react with each other — it does not ask whether Quebracho Blanco is a good idea for someone in your situation. Here is what our Quebracho Blanco record says about it on its own.

Quebracho Blanco: dosing

There is no well-established or standardized dose for quebracho blanco. The amount of active alkaloids can vary a lot between products, which makes safe dosing hard to determine.If you choose to use a quebracho product, follow the directions on the label and do not exceed the recommended amount.

From our Quebracho Blanco monograph — the full record covers uses, side effects and every documented interaction.

Read the full Quebracho Blanco monograph & all interactions
Medication

About Baclofen

What Is Baclofen Used For?

Brand name: Lioresal Injection

Baclofen treats spasticity, which means stiff, tight muscles with spasms. Oral baclofen (tablets, Baclofen oral solution, Ozobax, Baclofen oral suspension, Fleqsuvy, Lyvispah) is used for spasticity from multiple sclerosis, especially flexor spasms with pain, clonus (rhythmic jerking) and muscle rigidity. It may also help some people with spinal cord injuries and other spinal cord diseases.

Intrathecal baclofen (Gablofen, Lioresal Intrathecal and other baclofen injections) is used for severe spasticity. It is given into the fluid around the spinal cord, usually through an implanted pump. It is not for skeletal muscle spasm from rheumatic disorders, and baclofen tablets are not recommended for stroke, cerebral palsy or Parkinson’s disease.

See full Baclofen drug information
Keep checking

Other Drugs & Quebracho Blanco

Browse every other medication we’ve checked against Quebracho Blanco — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Quebracho Blanco against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Quebracho Blanco list.

See the full Quebracho Blanco interactions page
See every supplement checked against Lioresal, ranked by severity
Evidence & sources

Quebracho Blanco References

The 1 references that drive our Quebracho Blanco monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Quebracho Blanco and Lioresal Together: Common Questions

Is it safe to take Quebracho Blanco with Lioresal?
We do not list a known interaction between Quebracho Blanco and Lioresal. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Quebracho Blanco and Lioresal have any of the same side effects?
Yes — our sources link each of them separately to 6 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Lioresal interact with any supplements?
Yes. Lioresal has documented interactions with 10 supplements in our database — Quebracho Blanco is not one of them. The Lioresal interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Quebracho Blanco monograph Uses, safety profile, and every drug interaction in one place Baclofen drug information The full plain-English guide to this medication Lioresal supplement interactions Every supplement checked against Lioresal, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lioresal and Quebracho Blanco?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.