Drug & supplement interaction

Roman Chamomile + Valacyclovir

Valacyclovir brand name: Valtrex.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Roman Chamomile and Valacyclovir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Roman Chamomile and Valacyclovir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Valacyclovir and Roman Chamomile in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Roman Chamomile at all — not against Valacyclovir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Roman Chamomile safety at a glance

Roman Chamomile overall Use caution Generally well tolerated in tea or food amounts, but allergic reactions are possible in sensitive people.
Pregnancy Likely Unsafe When used orally in medicinal amounts. Roman chamomile is believed to be an abortifacient. Some population research has found a possible link between the use of... Read the full pregnancy detail
Breastfeeding Use caution Not enough reliable safety data, so use caution and ask your doctor first.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Valacyclovir and Roman Chamomile? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Roman Chamomile and Valacyclovir May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on Additional detail

    Roman Chamomile

    “Topically, Roman chamomile can cause contact dermatitis (4,567,97292). Allergic skin reactions can occur in up to 20% of individuals exposed to Roman chamomile (19). Multiple case reports have described the development of topical allergic reactions, including eczema and rash, with the use of cleaning products and cosmetics containing chamomile oil or chamomile extract.”

    Roman Chamomile · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 567. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
    3. 97292. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
    4. 19. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

    Valacyclovir

    Listed in the ADVERSE REACTIONS section of the FDA label for Valacyclovir. Read the label on DailyMed ›

  • A skin rash Additional detail

    Roman Chamomile

    Recorded for Roman Chamomile in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

    Valacyclovir

    Listed in the ADVERSE REACTIONS section of the FDA label for Valacyclovir. Read the label on DailyMed ›

  • Vomiting Additional detail

    Roman Chamomile

    “Orally, large amounts of Roman chamomile might cause vomiting, although data are conflicting (11,12).”

    Roman Chamomile · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    2 sources cited
    1. 11. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
    2. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

    Valacyclovir

    Listed in the ADVERSE REACTIONS section of the FDA label for Valacyclovir. Read the label on DailyMed ›

Reported for Roman Chamomile but not commonly for Valacyclovir: a stuffy or runny nose and cough.

Effects for Valacyclovir come from the ADVERSE REACTIONS section of its FDA label; effects for Roman Chamomile come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Roman Chamomile in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally in medicinal amounts. Roman chamomile is believed to be an abortifacient. Some population research has found a possible link between the use of Roman chamomile and an increased incidence of reduced birth weight, threatened miscarriage, and preterm labor. There is insufficient reliable information available about the safety of the topical use of Roman chamomile during pregnancy; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Roman Chamomile or Valacyclovir

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Roman Chamomile or Valacyclovir, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Valacyclovir

This page covers Roman Chamomile only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Valacyclovir page lists 27 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), African Wild Potato (moderate), Banderol (moderate), Biofeedback (moderate) and Caffeic Acid (moderate).

By severity: 1 major · 17 moderate · 9 minor.

From our pharmacist’s overview on the Valacyclovir page

“Valacyclovir (Valtrex) works against herpes outbreaks only if enough of it gets absorbed into your blood, and most of this list threatens exactly that. Of the 27 supplements on file, 17 can change how well oral medicines like this one are absorbed, and the single major-rated entry, activated charcoal, binds drugs in the gut outright.”

Reviewed by 2 · Jul 18, 2026

Open the Valacyclovir interaction page

One more smart check

Taking Roman Chamomile as Part of a Dietary Supplement Product? Check It for Interactions

We hold 8 real supplement products containing Roman Chamomile, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Roman Chamomile. Even though Roman Chamomile itself has no known interaction with Valacyclovir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Roman Chamomile and Valacyclovir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Roman Chamomile
Steady interest

#1,319 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Valacyclovir
Top 5%

#31 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Roman Chamomile reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Roman Chamomile and Valacyclovir records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Roman Chamomile

What is Roman Chamomile?

  • Digestive upset
  • Anxiety and relaxation
  • Sleep support
  • Skin irritation
  • Menstrual cramps

Roman chamomile is a daisy-family herb used traditionally as a calming tea and as an oil for digestion, mild anxiety, and skin comfort. Solid human evidence is limited for most uses, but it is generally considered safe in food and tea amounts for most adults. People allergic to ragweed and related plants should be cautious, and pregnant or breastfeeding people should check with a doctor first.

Chamaemelum nobile · Asteraceae · Flowers (and essential oil) · Tea, capsules, liquid extract, essential oil, topical creams

An interaction check asks whether these two react with each other — it does not ask whether Roman Chamomile is a good idea for someone in your situation. Here is what our Roman Chamomile record says about it on its own.

Roman Chamomile: dosing

There is no official standardized dose for Roman chamomile. The amount varies widely depending on the product and the form (tea, capsule, or extract).A common traditional use is one cup of chamomile tea made from the dried flowers, taken up to a few times a day. For capsules or liquid extracts, follow the directions on the product label, since strengths differ between brands.

From our Roman Chamomile monograph — the full record covers uses, side effects and every documented interaction.

Read the full Roman Chamomile monograph & all interactions
Medication

About Valacyclovir

What Is Valacyclovir Used For?

Brand name: Valtrex

Valacyclovir tablets are used in adults to treat cold sores (herpes labialis), genital herpes (initial and recurrent episodes), and shingles (herpes zoster). They can also be taken daily as suppressive therapy to reduce how often genital herpes outbreaks occur, and to lower the risk of passing genital herpes to a partner.

In children and adolescents, valacyclovir tablets are used to treat cold sores in those aged 12 and older, and chickenpox in those aged 2 to under 18. Valacyclovir has not been established as safe and effective for most uses in immunocompromised patients, with the exception of suppressive therapy for genital herpes in HIV-infected adults.

Most-Reported Side Effects for Valacyclovir

From FAERS, the FDA’s public side-effect reporting system (70,056 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 4,317 reports
Nausea 3,985 reports
Diarrhea 3,648 reports
Headache 2,964 reports
Fever 2,753 reports
See full Valacyclovir drug information
Keep checking

Other Drugs & Roman Chamomile

Browse every other medication we’ve checked against Roman Chamomile — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Roman Chamomile against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Roman Chamomile list.

See the full Roman Chamomile interactions page
See every supplement checked against Valacyclovir, ranked by severity
Evidence & sources

Roman Chamomile References

The 6 references that drive our Roman Chamomile monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
  6. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Roman Chamomile and Valacyclovir Together: Common Questions

Is it safe to take Roman Chamomile with Valacyclovir?
We do not list a known interaction between Roman Chamomile and Valacyclovir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Roman Chamomile and Valacyclovir have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Valacyclovir interact with any supplements?
Yes. Valacyclovir has documented interactions with 27 supplements in our database — Roman Chamomile is not one of them. The Valacyclovir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Roman Chamomile monograph Uses, safety profile, and every drug interaction in one place Valacyclovir drug information The full plain-English guide to this medication Valacyclovir supplement interactions Every supplement checked against Valacyclovir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Valacyclovir and Roman Chamomile?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.