Drug & supplement interaction

Roman Chamomile + Amoxicillin

Amoxicillin brand names: Amoxil Capsules, Trimox, Wymox, Amix, Amoram, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Roman Chamomile and Amoxicillin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Roman Chamomile and Amoxicillin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Amoxicillin and Roman Chamomile in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Roman Chamomile at all — not against Amoxicillin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Roman Chamomile safety at a glance

Roman Chamomile overall Use caution Generally well tolerated in tea or food amounts, but allergic reactions are possible in sensitive people.
Pregnancy Likely Unsafe When used orally in medicinal amounts. Roman chamomile is believed to be an abortifacient. Some population research has found a possible link between the use of... Read the full pregnancy detail
Breastfeeding Use caution Not enough reliable safety data, so use caution and ask your doctor first.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Amoxicillin and Roman Chamomile? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Roman Chamomile Itself Has Been Linked To

This is not an interaction — nothing below involves Amoxicillin. It is the side-effect record for Roman Chamomile on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Roman Chamomile, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on Additional detail

    “Topically, Roman chamomile can cause contact dermatitis (4,567,97292). Allergic skin reactions can occur in up to 20% of individuals exposed to Roman chamomile (19). Multiple case reports have described the development of topical allergic reactions, including eczema and rash, with the use of cleaning products and cosmetics containing chamomile oil or chamomile extract.”

    Roman Chamomile · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 567. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
    3. 97292. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
    4. 19. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  • A stuffy or runny nose / Cough Additional detail

    “A case report describes the development of cough and rhinitis in a 20-year-old female after exposure to chamomile-scented toilet paper. Skin prick testing confirmed the presence of allergenicity to the toilet paper product.”

    Roman Chamomile · Natural Medicines adverse-effect record, reported in cough.

    1 source cited
    1. 97292. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
  • A skin rash Additional detail

    Recorded for Roman Chamomile in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

  • Vomiting Additional detail

    “Orally, large amounts of Roman chamomile might cause vomiting, although data are conflicting (11,12).”

    Roman Chamomile · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    2 sources cited
    1. 11. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
    2. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Everything above comes from the Natural Medicines adverse-effect record for Roman Chamomile — expand a row for the licensed statement it rests on. We haven’t matched Amoxicillin to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Amoxicillin.

Special populations

Roman Chamomile in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally in medicinal amounts. Roman chamomile is believed to be an abortifacient. Some population research has found a possible link between the use of Roman chamomile and an increased incidence of reduced birth weight, threatened miscarriage, and preterm labor. There is insufficient reliable information available about the safety of the topical use of Roman chamomile during pregnancy; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Roman Chamomile or Amoxicillin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Roman Chamomile or Amoxicillin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Amoxicillin

This page covers Roman Chamomile only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amoxicillin page lists 96 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Khat (major) and Siberian Cocklebur (major).

By severity: 6 major · 76 moderate · 14 minor.

From our pharmacist’s overview on the Amoxicillin page

“Amoxicillin, one of the most commonly prescribed antibiotics, has 96 supplement and herbal ingredients flagged against it, and six carry a major rating, which puts this list in the read-carefully category. The serious entries mostly add strain to organs the drug already touches.”

Reviewed by 2 · Jul 18, 2026

Open the Amoxicillin interaction page

One more smart check

Taking Roman Chamomile as Part of a Dietary Supplement Product? Check It for Interactions

We hold 8 real supplement products containing Roman Chamomile, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Roman Chamomile. Even though Roman Chamomile itself has no known interaction with Amoxicillin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Roman Chamomile and Amoxicillin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Roman Chamomile
Steady interest

#1,321 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Amoxicillin
Top 5%

#36 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Roman Chamomile reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Roman Chamomile and Amoxicillin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Roman Chamomile

What is Roman Chamomile?

  • Digestive upset
  • Anxiety and relaxation
  • Sleep support
  • Skin irritation
  • Menstrual cramps

Roman chamomile is a daisy-family herb used traditionally as a calming tea and as an oil for digestion, mild anxiety, and skin comfort. Solid human evidence is limited for most uses, but it is generally considered safe in food and tea amounts for most adults. People allergic to ragweed and related plants should be cautious, and pregnant or breastfeeding people should check with a doctor first.

Chamaemelum nobile · Asteraceae · Flowers (and essential oil) · Tea, capsules, liquid extract, essential oil, topical creams

An interaction check asks whether these two react with each other — it does not ask whether Roman Chamomile is a good idea for someone in your situation. Here is what our Roman Chamomile record says about it on its own.

Roman Chamomile: dosing

There is no official standardized dose for Roman chamomile. The amount varies widely depending on the product and the form (tea, capsule, or extract).A common traditional use is one cup of chamomile tea made from the dried flowers, taken up to a few times a day. For capsules or liquid extracts, follow the directions on the product label, since strengths differ between brands.

From our Roman Chamomile monograph — the full record covers uses, side effects and every documented interaction.

Read the full Roman Chamomile monograph & all interactions
Medication

About Amoxicillin

What Is Amoxicillin Used For?

Brand names: Amoxil Capsules, Trimox, Wymox, Amix, Amoram, Amoxident, Galenamox, Rimoxallin, Amoxil Injection

Amoxicillin treats bacterial infections in both adults and children, including ear, nose, and throat infections; lower respiratory tract infections; skin and skin structure infections; and genitourinary tract infections.

In adults only, amoxicillin is also used — always combined with other medications — to eradicate Helicobacter pylori (H. pylori), the bacteria behind duodenal ulcers. Getting rid of H. pylori has been shown to reduce the chance of those ulcers coming back. It is only effective against bacteria that are susceptible to it and will not work against viral infections like the common cold or flu.

Most-Reported Side Effects for Amoxicillin

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 6,010 reports
Drug hypersensitivity 5,482 reports
Nausea 5,158 reports
Dyspnea 5,001 reports
Acute kidney injury 4,989 reports
See full Amoxicillin drug information
Keep checking

Other Drugs & Roman Chamomile

Browse every other medication we’ve checked against Roman Chamomile — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Roman Chamomile against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Roman Chamomile list.

See the full Roman Chamomile interactions page
See every supplement checked against Amoxicillin, ranked by severity
Evidence & sources

Roman Chamomile References

The 6 references that drive our Roman Chamomile monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
  6. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Roman Chamomile and Amoxicillin Together: Common Questions

Is it safe to take Roman Chamomile with Amoxicillin?
We do not list a known interaction between Roman Chamomile and Amoxicillin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Amoxicillin interact with any supplements?
Yes. Amoxicillin has documented interactions with 96 supplements in our database — Roman Chamomile is not one of them. The Amoxicillin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Roman Chamomile monograph Uses, safety profile, and every drug interaction in one place Amoxicillin drug information The full plain-English guide to this medication Amoxicillin supplement interactions Every supplement checked against Amoxicillin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Amoxicillin and Roman Chamomile?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.