Drug & supplement interaction

Royal Jelly + Aluminum Acetate

Aluminum Acetate brand name: Burow's Solution.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Royal Jelly and Aluminum Acetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Royal Jelly and Aluminum Acetate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Aluminum Acetate and Royal Jelly in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Royal Jelly safety at a glance

Royal Jelly overall Use caution Generally well tolerated, but it can trigger serious allergic reactions in sensitive people.

Pregnancy Avoid Not enough safety information; best to avoid during pregnancy.

Breastfeeding Avoid Not enough safety information; best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Aluminum Acetate and Royal Jelly? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Aluminum Acetate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Aluminum Acetate is filed under a single classification — topical drugs. Royal Jelly has documented interactions with 2 drug classes — the most serious being antihypertensive drugs (moderate) and warfarin (coumadin) (moderate) — and none of Aluminum Acetate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Royal Jelly Does Interact With Other Medications

Royal Jelly has 174 moderate known drug interactions in our database — Aluminum Acetate isn’t one of them. If you take anything else, check it against the full list below.

Moderate 174 No known interaction 2,656 (incl. Aluminum Acetate)

Taking anything else?

Check Another of Your Medications Against Royal Jelly

Covers the 2,830 medications we’ve checked against Royal Jelly. Pick one to open its full report.

What to actually watch for

What Royal Jelly Itself Has Been Linked To

This is not an interaction — nothing below involves Aluminum Acetate. It is the side-effect record for Royal Jelly on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Royal Jelly, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

Wheezing / Shortness of breath / A severe allergic reaction / Hives Worth acting on Additional detail
“In people with a history of atopy or asthma, royal jelly taken orally appears to cause a high rate of allergic symptoms including pruritus, urticaria, eczema, eyelid and facial edema, conjunctivitis, rhinorrhea, dyspnea, oral allergy syndrome, and asthma. In severe cases, royal jelly can cause status asthmaticus, anaphylaxis, and death.”

Royal Jelly · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).
6 sources cited

792. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI

7315. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.

7316. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI

10623. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed

10624. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI

108511. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed
An allergic reaction Worth acting on Additional detail

Recorded for Royal Jelly in the same Natural Medicines adverse-effect record shown under Wheezing / Shortness of breath / A severe allergic reaction / Hives above.
Itching Additional detail

Recorded for Royal Jelly in the same Natural Medicines adverse-effect record shown under Wheezing / Shortness of breath / A severe allergic reaction / Hives above.
Swelling Additional detail

Recorded for Royal Jelly in the same Natural Medicines adverse-effect record shown under Wheezing / Shortness of breath / A severe allergic reaction / Hives above.
Stomach pain / Diarrhea Additional detail
“There is one case report of hemorrhagic colitis with abdominal pain, bloody diarrhea with concomitant hemorrhagic and edematous mucosa of the sigmoid colon after ingestion of royal jelly. Symptoms resolved within 2 weeks following discontinuation of royal jelly and conservative treatment.”

Royal Jelly · Natural Medicines adverse-effect record, reported in diarrhea.
1 source cited

3516. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
Dizziness Additional detail
“There is one report of dizziness in a patient who took a combination product containing royal jelly, bee pollen extract, and a bee pollen plus pistil extract.”

Royal Jelly · Natural Medicines adverse-effect record, reported in vertigo.
1 source cited

12008. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI

Showing the 10 most notable of 11 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Royal Jelly — expand a row for the licensed statement it rests on. We haven’t matched Aluminum Acetate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Aluminum Acetate.

Everything else you take

See Every Supplement That Interacts With Aluminum Acetate

This page covers Royal Jelly only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aluminum Acetate page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Aluminum Acetate page

“Aluminum acetate (Burow's Solution) is the soak or compress people reach for with weepy rashes, athlete's foot, or swimmer's ear, and its three supplement interactions on file all come down to what else touches that same patch of skin. None is rated major, and this is a list most people can handle with a little attention rather than al…”

Reviewed by 2 · Jul 18, 2026

Open the Aluminum Acetate interaction page

One more smart check

Taking Royal Jelly as Part of a Dietary Supplement Product? Check It for Interactions

We hold 677 real supplement products containing Royal Jelly, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Royal Jelly. Even though Royal Jelly itself has no known interaction with Aluminum Acetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Royal Jelly and Aluminum Acetate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Royal Jelly

Top 25%

#294 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Aluminum Acetate

Steady interest

#1,632 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Royal Jelly reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Royal Jelly and Aluminum Acetate records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Royal Jelly

What is Royal Jelly?

Menopausal symptoms
Skin health and wound care
Immune support
General energy and vitality
Cholesterol support
Eye dryness (eye drops)

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune support, but solid human evidence is limited for most uses. It is generally well tolerated by most people, but it can cause serious allergic reactions, especially in those allergic to bees or with asthma.

Secretion from the glands of worker honey bees (Apis mellifera) · Capsules, softgels, fresh (frozen) jelly, liquid, powder, and skin creams

An interaction check asks whether these two react with each other — it does not ask whether Royal Jelly is a good idea for someone in your situation. Here is what our Royal Jelly record says about it on its own.

Royal Jelly: dosing

There is no official or standardized dose of royal jelly. The amounts used in studies have varied widely, and products differ in their strength and purity.Because there is no proven best dose, it is wise to follow the directions on the product label and not take more than recommended.

From our Royal Jelly monograph — the full record covers uses, side effects and every documented interaction.

Read the full Royal Jelly monograph & all interactions

Medication

About Aluminum Acetate

What Is Aluminum Acetate Used For?

Brand name: Burow's Solution

Aluminum acetate is applied to the skin to temporarily ease the itch, irritation, and discomfort of a range of common skin conditions. Most products — including Tricalm Hydrogel, TriCalm, and Dermeleve cream — are used for poison ivy, poison oak, poison sumac, insect bites, athlete's foot, and rashes caused by soaps, detergents, cosmetics, or jewelry.

Dermeleve cream also lists minor burns among its uses. Dermeleve Anti Itch Scalp Serum is specifically formulated for scalp itch and rashes from soaps, detergents, or cosmetics applied to the scalp. The ZO Skin Health powder products target rashes from soaps, detergents, cosmetics, or jewelry.

Most-Reported Side Effects for Aluminum Acetate

From FAERS, the FDA’s public side-effect reporting system (40 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Headache 19 reports

Hypersensitivity 16 reports

Nausea 16 reports

Therapeutic product effect decreased 16 reports

Contraindicated product administered 6 reports

See full Aluminum Acetate drug information

Keep checking

Other Drugs & Royal Jelly

Browse every other medication we’ve checked against Royal Jelly — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

174Moderate

0Minor

2,655No known interaction

174 Moderate 2,655 No interaction

Moderate

174 interactions

Showing 60 of 174 moderate interactions — see all 174 on the Royal Jelly page.

No interaction 2,655 drugs checked — show the list

We also checked Royal Jelly against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,655 medications checked with no known interaction — see the full Royal Jelly list.

See the full Royal Jelly interactions page

See every supplement checked against Aluminum Acetate, ranked by severity

Evidence & sources

Royal Jelly References

The 14 references that drive our Royal Jelly monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Royal Jelly and Aluminum Acetate Together: Common Questions

Is it safe to take Royal Jelly with Aluminum Acetate?

We do not list a known interaction between Royal Jelly and Aluminum Acetate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

How was the Royal Jelly and Aluminum Acetate combination checked?

Interactions in our licensed database are recorded against drug classes. Aluminum Acetate is filed under 1 classification, and Royal Jelly has documented interactions with 2 drug classes — none of Aluminum Acetate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Royal Jelly interact with any other medications?

Yes. Royal Jelly has 174 documented drug interactions in our database — Aluminum Acetate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Aluminum Acetate interact with any supplements?

Yes. Aluminum Acetate has documented interactions with 3 supplements in our database — Royal Jelly is not one of them. The Aluminum Acetate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Royal Jelly monograph Uses, safety profile, and every drug interaction in one place Aluminum Acetate drug information The full plain-English guide to this medication Aluminum Acetate supplement interactions Every supplement checked against Aluminum Acetate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 14 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Aluminum Acetate and Royal Jelly?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.