Royal Jelly + Eltrombopag
Eltrombopag brand names: Promacta, Revolade, Alvaiz.
We found no known interaction between Royal Jelly and Eltrombopag in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Eltrombopag states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Royal Jelly and Eltrombopag
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Eltrombopag and Royal Jelly in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Royal Jelly safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Eltrombopag
Interactions in our licensed database are recorded against drug classes, not just single drug names. Eltrombopag is filed under 2 classifications — hepatotoxic drugs, oral drugs. Royal Jelly has documented interactions with 2 drug classes — the most serious being antihypertensive drugs (moderate) and warfarin (coumadin) (moderate) — and none of Eltrombopag’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Royal Jelly Does Interact With Other Medications
Royal Jelly has 174 moderate known drug interactions in our database — Eltrombopag isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Royal Jelly
We haven’t checked that one against Royal Jelly yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Royal Jelly. Pick one to open its full report.
Some Eltrombopag Products Have a Food Rule — Royal Jelly Should Not Break It
At least one FDA label for a product containing Eltrombopag says to take it with food. If you take Royal Jelly on an empty stomach out of habit, keep them separate — and take Eltrombopag with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Eltrombopag products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Do not split, chew, or crush tablets and mix with food or liquids.
From the Dosage and Administration section of the FDA label we read for Eltrombopag — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
What Eltrombopag Is Prescribed For, and What Royal Jelly Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Eltrombopag is a prescription medicine with approved uses on its FDA label. Royal Jelly is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Eltrombopag is prescribed for: Eltrombopag treats thrombocytopenia (low platelet counts) in several different conditions. It is used for adults and children (age 1 and older, depending on the product) with persistent or chronic immune thrombocytopenia (ITP) — a condition where the immune system destroys platelets — when other treatments like steroids or immunoglobulins haven't worked well enough. It is also used to raise platelet counts in adults with chronic hepatitis C whose low platelet count prevents them from starting or staying on interferon-based antiviral therapy. Eltrombopag tablets (including Promacta) are also approved — alone or combined with immunosuppressive therapy — for adults and certain children (age 2 and older) with severe aplastic anemia, a serious bone marrow failure condition.
Read the rest of what Eltrombopag is prescribed for
Alvaiz (a specific brand) shares most of these uses but has product-specific dosing that is not interchangeable milligram-for-milligram with other eltrombopag products. The oral suspension formulation is approved for ITP and for refractory severe aplastic anemia, but is not approved for first-line severe aplastic anemia in combination with immunosuppressive therapy.
Royal Jelly has been studied for:
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Hepatitis studied, not established Royal Jelly has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Royal Jelly for hepatitis
Although there has been interest in using oral royal jelly for hepatitis, there is insufficient reliable information about the clinical effects of royal jelly for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Eltrombopag on your own; if you are taking Royal Jelly for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
See Every Supplement That Interacts With Eltrombopag
This page covers Royal Jelly only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Eltrombopag page lists 55 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Ashwagandha (moderate).
By severity: 4 major · 42 moderate · 9 minor.
From our pharmacist’s overview on the Eltrombopag page
“Eltrombopag (Promacta, Revolade) boosts platelet production, and because the drug itself can stress the liver, this list warrants genuine care. Thirty-eight of the 55 supplements and herbs here can injure the liver on their own, so combining them stacks risk on an organ your doctor is already watching with blood tests.”
Reviewed by 2 · Jul 18, 2026
Taking Royal Jelly as Part of a Dietary Supplement Product? Check It for Interactions
We hold 677 real supplement products containing Royal Jelly, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Royal Jelly. Even though Royal Jelly itself has no known interaction with Eltrombopag, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Royal Jelly and Eltrombopag Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#310 of 1,452 supplements looked up here in the last 7 days
#2,384 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Royal Jelly reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Royal Jelly and Eltrombopag records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Royal Jelly
What is Royal Jelly?
- Menopausal symptoms
- Skin health and wound care
- Immune support
- General energy and vitality
- Cholesterol support
- Eye dryness (eye drops)
Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune support, but solid human evidence is limited for most uses. It is generally well tolerated by most people, but it can cause serious allergic reactions, especially in those allergic to bees or with asthma.
Secretion from the glands of worker honey bees (Apis mellifera) · Capsules, softgels, fresh (frozen) jelly, liquid, powder, and skin creams
An interaction check asks whether these two react with each other — it does not ask whether Royal Jelly is a good idea for someone in your situation. Here is what our Royal Jelly record says about it on its own.
Royal Jelly: dosing
There is no official or standardized dose of royal jelly. The amounts used in studies have varied widely, and products differ in their strength and purity.Because there is no proven best dose, it is wise to follow the directions on the product label and not take more than recommended.
From our Royal Jelly monograph — the full record covers uses, side effects and every documented interaction.
About Eltrombopag
What Is Eltrombopag Used For?
Brand names: Promacta, Revolade, Alvaiz
Eltrombopag treats thrombocytopenia (low platelet counts) in several different conditions. It is used for adults and children (age 1 and older, depending on the product) with persistent or chronic immune thrombocytopenia (ITP) — a condition where the immune system destroys platelets — when other treatments like steroids or immunoglobulins haven't worked well enough. It is also used to raise platelet counts in adults with chronic hepatitis C whose low platelet count prevents them from starting or staying on interferon-based antiviral therapy.
Eltrombopag tablets (including Promacta) are also approved — alone or combined with immunosuppressive therapy — for adults and certain children (age 2 and older) with severe aplastic anemia, a serious bone marrow failure condition. Alvaiz (a specific brand) shares most of these uses but has product-specific dosing that is not interchangeable milligram-for-milligram with other eltrombopag products. The oral suspension formulation is approved for ITP and for refractory severe aplastic anemia, but is not approved for first-line severe aplastic anemia in combination with immunosuppressive therapy.
Other Drugs & Royal Jelly
Browse every other medication we’ve checked against Royal Jelly — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
174 interactions
- Diltiazem ›
- Nifedipine ›
- Propranolol ›
- Hydrochlorothiazide ›
- Verapamil ›
- Hydralazine ›
- Trichlormethiazide ›
- Bendroflumethiazide ›
- Lisinopril ›
- Metolazone ›
- Minoxidil ›
- Nicardipine ›
- Prazosin ›
- Spironolactone ›
- Timolol ›
- Warfarin Sodium ›
- Acebutolol ›
- Acetazolamide ›
- Ambrisentan ›
- Amiloride ›
- Atenolol ›
- Betaxolol ›
- Candesartan Cilexetil ›
- Captopril ›
- Carteolol ›
- Carvedilol ›
- Chlorthalidone ›
- Cyclothiazide ›
- Enalapril Maleate ›
- Felodipine ›
- Guanethidine Monosulfate ›
- Iloprost ›
- Indapamide ›
- Irbesartan ›
- Labetalol ›
- Mannitol ›
- Methyclothiazide ›
- Methyldopa ›
- Metoprolol ›
- Nadolol ›
- Nebivolol ›
- Nimodipine ›
- Olmesartan Medoxomil ›
- Oxprenolol ›
- Pindolol ›
- Quinapril ›
- Reserpine ›
- Terazosin ›
- Torsemide ›
- Treprostinil (oral) ›
- Valsartan ›
- Aliskiren ›
- Amlodipine ›
- Amlodipine Benzoate ›
- Amlodipine Besilate ›
- Amlodipine Besylate ›
- Ammonium Chloride ›
- Aprocitentan ›
- Azilsartan ›
- Benazepril ›
Showing 60 of 174 moderate interactions — see all 174 on the Royal Jelly page.
No interaction 2,655 drugs checked — show the list
We also checked Royal Jelly against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Isotretinoin ›
- Methotrexate ›
- Bupropion ›
- Bendamustine ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Acetaminophen, Aspirin, Caffeine ›
- Acetaminophen, Oxycodone ›
- Amoxicillin, Clavulanate Potassium ›
- Diazepam ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Dapsone ›
- Cyclopentolate ›
Showing the 60 most looked-up of 2,655 medications checked with no known interaction — see the full Royal Jelly list.
Royal Jelly References
The 14 references that drive our Royal Jelly monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
- Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
- Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
- Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
- Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
- Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
- Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
- Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
- Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
- Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
- Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
- Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
- Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
- Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Royal Jelly and Eltrombopag Together: Common Questions
Is it safe to take Royal Jelly with Eltrombopag?
Do Royal Jelly and Eltrombopag have any of the same side effects?
Should I take Royal Jelly and Eltrombopag at the same time of day?
Are Royal Jelly and Eltrombopag used for the same thing?
How was the Royal Jelly and Eltrombopag combination checked?
Does Royal Jelly interact with any other medications?
Does Eltrombopag interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.