Drug & supplement interaction

Scurvy Grass + Imipramine

Imipramine brand names: Tofranil, Tofranil PM.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Scurvy Grass and Imipramine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Scurvy Grass and Imipramine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Imipramine and Scurvy Grass in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Scurvy Grass at all — not against Imipramine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Scurvy Grass safety at a glance

Scurvy Grass overall Use caution Generally eaten as a food historically, but modern safety data for medicinal use is limited.
Pregnancy Avoid Not enough safety information; avoid medicinal amounts during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid medicinal amounts while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Imipramine and Scurvy Grass? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Imipramine’s Own FDA Label Lists

This is not an interaction — none of it involves Scurvy Grass. These are the most notable effects listed in the ADVERSE REACTIONS section of Imipramine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Dependence or withdrawal symptoms Worth acting on
  • A bowel blockage Worth acting on
  • Trouble passing urine Worth acting on
  • Low sodium Worth acting on
  • Unsteadiness Worth acting on
  • A heart attack Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Heart failure Worth acting on

Showing the 10 most notable of 52 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Imipramine. Read the label on DailyMed › Scurvy Grass’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Scurvy Grass side to compare — that is a limit of the record, not a statement that Scurvy Grass has no side effects.

From our Q&A

Questions About Scurvy Grass or Imipramine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Scurvy Grass or Imipramine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Imipramine

This page covers Scurvy Grass only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Imipramine page lists 254 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 11 major · 190 moderate · 53 minor.

From our pharmacist’s overview on the Imipramine page

“Imipramine (Tofranil) is an older tricyclic antidepressant, and the supplements on this page deserve real scrutiny before you add one. Most of the list acts on the liver enzymes that process the drug, so an ingredient can quietly raise or lower imipramine levels: grapefruit pushes them up, while St.”

Reviewed by 2 · Jul 18, 2026

Open the Imipramine interaction page

How much people look this up

Where Scurvy Grass and Imipramine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Scurvy Grass
Top half

#653 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Imipramine
Steady interest

#1,843 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Scurvy Grass reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Scurvy Grass and Imipramine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Scurvy Grass

What is Scurvy Grass?

  • Historical scurvy prevention (vitamin C source)
  • General tonic
  • Mouth and gum health
  • Digestive support
  • Mild antiseptic/wound rinse

Scurvy grass is a traditional European herb historically eaten by sailors as a source of vitamin C to prevent scurvy. Today it has little proven medical use beyond its vitamin C content, and modern research is very limited. If you simply need vitamin C, well-studied foods and supplements are more reliable.

Cochlearia officinalis · Brassicaceae · Leaves and aerial parts (fresh herb) · Fresh leaves, tea, tincture, juice, dried herb

An interaction check asks whether these two react with each other — it does not ask whether Scurvy Grass is a good idea for someone in your situation. Here is what our Scurvy Grass record says about it on its own.

Scurvy Grass: dosing

There is no established standardized dose for scurvy grass. Historically it was used as a fresh leafy green or its juice, in everyday food-like amounts, rather than measured medicinal doses.If you use a commercial product such as a tea or tincture, follow the directions on the label and do not exceed the suggested amount.

From our Scurvy Grass monograph — the full record covers uses, side effects and every documented interaction.

Read the full Scurvy Grass monograph & all interactions
Medication

About Imipramine

What Is Imipramine Used For?

Brand names: Tofranil, Tofranil PM

Imipramine is used to relieve symptoms of depression. Both Imipramine Hydrochloride tablets and Imipramine Pamoate capsules are approved for this use. Endogenous depression — the kind that seems to arise from within rather than a clear outside cause — tends to respond especially well. It may take one to three weeks before you notice the full benefit.

Imipramine Hydrochloride tablets are also approved as a short-term, add-on treatment to help reduce nighttime bedwetting (nocturnal enuresis) in children aged 6 and older, after a doctor has ruled out physical causes.

See full Imipramine drug information
Keep checking

Other Drugs & Scurvy Grass

Browse every other medication we’ve checked against Scurvy Grass — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Scurvy Grass References

The 1 references that drive our Scurvy Grass monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Scurvy Grass and Imipramine Together: Common Questions

Is it safe to take Scurvy Grass with Imipramine?
We do not list a known interaction between Scurvy Grass and Imipramine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Imipramine interact with any supplements?
Yes. Imipramine has documented interactions with 254 supplements in our database — Scurvy Grass is not one of them. The Imipramine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Imipramine and Scurvy Grass?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.