Drug & supplement interaction

Self-heal + Dostarlimab-Gxly

Dostarlimab-Gxly brand name: Jemperli.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Self-heal and Dostarlimab-Gxly in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Self-heal and Dostarlimab-Gxly

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dostarlimab-Gxly and Self-heal in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Self-heal at all — not against Dostarlimab-Gxly, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Self-heal safety at a glance

Self-heal overall Use caution Generally used in foods and teas, but human safety data are limited.

Pregnancy Avoid Not enough safety information, so it is best avoided.

Breastfeeding Avoid No reliable safety data, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dostarlimab-Gxly and Self-heal? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

What Self-heal Itself Has Been Linked To

This is not an interaction — nothing below involves Dostarlimab-Gxly. It is the side-effect record for Self-heal on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Self-heal, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

An allergic reaction Worth acting on Additional detail
“Orally, self-heal has been reported to cause nausea, vomiting, and diarrhea. Orally and topically, self-heal has been reported to cause allergic reactions in sensitive individuals (12).”

Self-heal · Natural Medicines adverse-effect record, reported in diarrhea.
1 source cited

12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Reduced appetite / Stomach upset Additional detail
“Orally, self-heal has been reported to cause nausea, vomiting, and diarrhea (12). A combination product containing self-heal, Clematis mandshurica, and Chinese cucumber has been reported to cause epigastric pain, abdominal discomfort, nausea, reduced appetite, and dyspepsia. It is not clear if these effects are due to self-heal, the other ingredients, or the combination.”

Self-heal · Natural Medicines adverse-effect record, reported in diarrhea.
2 sources cited

12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

101041. Song YW, Lee EY, Koh EM, et al. Assessment of comparative pain relief and tolerability of SKI306X compared with celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, double-dummy, phase III, noninferiority clini
Diarrhea / Vomiting / Nausea Additional detail

Recorded for Self-heal in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

Everything above comes from the Natural Medicines adverse-effect record for Self-heal — expand a row for the licensed statement it rests on. We haven’t matched Dostarlimab-Gxly to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Dostarlimab-Gxly.

One more smart check

Taking Self-heal as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Self-heal, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Self-heal. Even though Self-heal itself has no known interaction with Dostarlimab-Gxly, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Self-heal and Dostarlimab-Gxly Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Self-heal

Steady interest

#848 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Dostarlimab-Gxly

Top 25%

#486 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Self-heal reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Self-heal and Dostarlimab-Gxly records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Self-heal

What is Self-heal?

Sore throat and mouth infections
Cold sores and skin irritation
Inflammation
General immune support
Minor wounds (topical)

Self-heal (Prunella vulgaris) is a traditional herb used for sore throats, skin issues, and inflammation, mainly in folk and traditional Chinese medicine. Human evidence for its benefits is very limited, so it should be viewed as an unproven remedy. If you want to try it, talk with your pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Prunella vulgaris · Lamiaceae · Aerial parts (flowering spikes, leaves, and stems) · Tea, tincture, capsules, dried herb, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Self-heal is a good idea for someone in your situation. Here is what our Self-heal record says about it on its own.

Self-heal: dosing

There is no well-established, standardized dose for self-heal. Traditional use as a tea involves steeping the dried herb in hot water, but commercial products vary widely in strength and form.If you choose to use a product, follow the directions on the label and do not exceed the recommended amount.

From our Self-heal monograph — the full record covers uses, side effects and every documented interaction.

Read the full Self-heal monograph & all interactions

Medication

About Dostarlimab-gxly Injection

What Is Dostarlimab-gxly Injection Used For?

Brand name: Jemperli

Dostarlimab-gxly injection is used to treat a certain type of endometrial cancer (cancer that begins in the lining of the uterus) in adults that has progressed or has returned after treatment with other chemotherapy medication(s). Dostarlimab-gxly injection is also used to treat a certain type of solid tumor that has spread to other parts of the body in adults who were previously treated unsuccessfully with another chemotherapy medication and do not have other satisfactory treatment options. Dostarlimab-gxly injection is in a class of medications called monoclonal antibodies. It works by blocking the action of a certain protein in cancer cells. This helps the person's immune system to fight against the cancer cells, and helps to slow tumor growth.

See full Dostarlimab-gxly Injection drug information

Keep checking

Other Drugs & Self-heal

Browse every other medication we’ve checked against Self-heal — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Self-heal against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Self-heal list.

See the full Self-heal interactions page

See every supplement checked against Dostarlimab-Gxly, ranked by severity

Evidence & sources

Self-heal References

The 2 references that drive our Self-heal monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Song YW, Lee EY, Koh EM, et al. Assessment of comparative pain relief and tolerability of SKI306X compared with celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, double-dummy, phase III, noninferiority clini

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Self-heal and Dostarlimab-Gxly Together: Common Questions

Is it safe to take Self-heal with Dostarlimab-Gxly?

We do not list a known interaction between Self-heal and Dostarlimab-Gxly. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Self-heal monograph Uses, safety profile, and every drug interaction in one place Dostarlimab-gxly Injection drug information The full plain-English guide to this medication Dostarlimab-Gxly supplement interactions Every supplement checked against Dostarlimab-Gxly, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dostarlimab-Gxly and Self-heal?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.