Drug & supplement interaction

Spleen Extract + Oxaliplatin

Oxaliplatin brand name: Eloxatin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Spleen Extract and Oxaliplatin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Spleen Extract and Oxaliplatin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Oxaliplatin and Spleen Extract in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Spleen Extract at all — not against Oxaliplatin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Spleen Extract safety at a glance

Spleen Extract overall Use caution Human evidence is limited and animal-tissue products carry possible contamination and infection concerns.
Pregnancy Avoid There is no safety data in pregnancy, so it is best avoided.
Breastfeeding Avoid No safety information exists for breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Oxaliplatin and Spleen Extract? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Oxaliplatin’s Own FDA Label Lists

This is not an interaction — none of it involves Spleen Extract. These are the most notable effects listed in the ADVERSE REACTIONS section of Oxaliplatin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 9 of them are worth acting on rather than waiting out — marked below.

  • Severe muscle breakdown Worth acting on
  • Bleeding in the gut Worth acting on
  • A low platelet count Worth acting on
  • Anemia Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Mouth irritation or sores

Showing the 10 most notable of 16 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Oxaliplatin. Read the label on DailyMed › Spleen Extract’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Spleen Extract side to compare — that is a limit of the record, not a statement that Spleen Extract has no side effects.

Everything else you take

See Every Supplement That Interacts With Oxaliplatin

This page covers Spleen Extract only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Oxaliplatin page lists 10 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Acerola (moderate), Alpha-lipoic Acid (moderate), Coenzyme Q10 (moderate), Dimethylsulfoxide (dmso) (moderate) and Rose Hip (moderate).

By severity: 8 moderate · 2 minor.

From our pharmacist’s overview on the Oxaliplatin page

“Most of the ten supplements on record for oxaliplatin (Eloxatin), a chemotherapy used against colorectal cancer, are antioxidants such as vitamin C, vitamin E, and coenzyme Q10, and the concern with each is the same, that they might in theory blunt the drug's ability to kill tumor cells. None of the ten is rated major, eight sit at mod…”

Reviewed by 2 · Jul 18, 2026

Open the Oxaliplatin interaction page

One more smart check

Taking Spleen Extract as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Spleen Extract, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Spleen Extract. Even though Spleen Extract itself has no known interaction with Oxaliplatin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Spleen Extract and Oxaliplatin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Spleen Extract
Steady interest

#1,249 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Oxaliplatin
Top half

#1,312 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Spleen Extract reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Spleen Extract and Oxaliplatin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Spleen Extract

What is Spleen Extract?

  • Immune support
  • Low white blood cell counts
  • General "glandular" support
  • Boosting energy or vitality

Spleen extract is a glandular supplement made from the spleen tissue of animals such as cows or pigs, promoted mainly for immune support. There is very little reliable human research to show it works, and because it is an animal tissue product there are real safety questions, including possible infection risk. Talk with your pharmacist or doctor before using it.

Spleen tissue, usually from cattle (bovine) or pigs (porcine) · Capsules, tablets, sometimes injectable forms (older or non-standard products)

An interaction check asks whether these two react with each other — it does not ask whether Spleen Extract is a good idea for someone in your situation. Here is what our Spleen Extract record says about it on its own.

Spleen Extract: dosing

There is no established or standardized dose for spleen extract. Products vary widely in how they are made and what they contain.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.

From our Spleen Extract monograph — the full record covers uses, side effects and every documented interaction.

Read the full Spleen Extract monograph & all interactions
Medication

About Oxaliplatin Injection

What Is Oxaliplatin Injection Used For?

Brand name: Eloxatin

Oxaliplatin Injection is used in combination with two other drugs — fluorouracil and leucovorin — to treat colon and colorectal cancers. It is approved for adjuvant treatment (treatment after surgery to lower the chance of cancer returning) of stage III colon cancer in patients who have had the tumor completely removed.

It is also used to treat advanced colorectal cancer (cancer that has spread or cannot be cured with surgery alone). In both settings, oxaliplatin is always given as part of a combination regimen — it is not used alone.

See full Oxaliplatin Injection drug information
Keep checking

Other Drugs & Spleen Extract

Browse every other medication we’ve checked against Spleen Extract — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Spleen Extract References

The 1 references that drive our Spleen Extract monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Spleen Extract and Oxaliplatin Together: Common Questions

Is it safe to take Spleen Extract with Oxaliplatin?
We do not list a known interaction between Spleen Extract and Oxaliplatin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Oxaliplatin interact with any supplements?
Yes. Oxaliplatin has documented interactions with 10 supplements in our database — Spleen Extract is not one of them. The Oxaliplatin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Oxaliplatin and Spleen Extract?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.