Drug & supplement interaction

Stem Cell Therapy + Bortezomib

Bortezomib brand name: Velcade.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Stem Cell Therapy and Bortezomib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Stem Cell Therapy and Bortezomib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Bortezomib and Stem Cell Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Stem Cell Therapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Stem Cell Therapy at all — not against Bortezomib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Stem Cell Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Stem Cell Therapy safety at a glance

Stem Cell Therapy overall Use caution Proven uses exist, but most marketed stem cell treatments are unproven and can carry serious risks.
Pregnancy Avoid Unproven stem cell treatments should be avoided during pregnancy unless medically necessary and supervised by specialists.
Breastfeeding Avoid Avoid elective stem cell procedures while breastfeeding; safety has not been established.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Bortezomib and Stem Cell Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Stem Cell Therapy and Bortezomib May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so having Stem Cell Therapy while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on Additional detail

    Stem Cell Therapy

    “Injected direct-to-consumer stem cell preparations have been associated with reports of sepsis, pneumonia, necrotizing ulcers, meningitis, and other infections. Intra-articular injections of contaminated stem cells have resulted in mutiple cases of infections, most of which were bloodstream infections.”

    Stem Cell Therapy · Natural Medicines adverse-effect record, reported in cirrhosis.

    3 sources cited
    1. 99561. Perkins KM, Spoto S, Rankin DA, et al. Notes from the Field: Infections After Receipt of Bacterially Contaminated Umbilical Cord Blood-Derived Stem Cell Products for Other Than Hematopoietic or Immunologic Reconstitution - United States, 2018. MMWR Morb M
    2. 99543. Bauer G, Elsallab M, Abou-El-Enein M. Concise Review: A Comprehensive Analysis of Reported Adverse Events in Patients Receiving Unproven Stem Cell-Based Interventions. Stem Cells Transl Med. 2018;7(9):676-685. PubMed
    3. 109539. Richardson E, Project Director. Harms linked to unapproved stem cell interventions highlight need for greater FDA enforcement. The Pew Charitable Trusts Brief. June 2021. Available at: https://www.pewtrusts.org/en/research-and-analysis/issue-briefs/2021/0

    Bortezomib

    Listed in the ADVERSE REACTIONS section of the FDA label for Bortezomib. Read the label on DailyMed ›

  • Numbness or tingling Additional detail

    Stem Cell Therapy

    “Injected direct-to-consumer stem cell preparations have been associated with reports of stroke, brain hemorrhage, and other neurological complications. In one case report, a 69-year-old female with leg numbness and difficulty walking from chemotherapy complications developed a stroke and died after receiving grossly filtered bone marrow aspirate injected into her right carotid artery.”

    Stem Cell Therapy · Natural Medicines adverse-effect record, reported in chemotherapy-related complications.

    2 sources cited
    1. 99543. Bauer G, Elsallab M, Abou-El-Enein M. Concise Review: A Comprehensive Analysis of Reported Adverse Events in Patients Receiving Unproven Stem Cell-Based Interventions. Stem Cells Transl Med. 2018;7(9):676-685. PubMed
    2. 102553. Madhavan AA, Summerfield D, Hunt CH, et al. Polyclonal lymphocytic infiltrate with arachnoiditis resulting from intrathecal stem cell transplantation. Neuroradiol J. 2020 Apr;33(2):174-178. PubMed

    Bortezomib

    Listed in the ADVERSE REACTIONS section of the FDA label for Bortezomib. Read the label on DailyMed ›

Reported for Stem Cell Therapy but not commonly for Bortezomib: a severe skin reaction, blood clots, a heart attack and loss of bladder control.

Effects for Bortezomib come from the ADVERSE REACTIONS section of its FDA label; effects for Stem Cell Therapy come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Bortezomib

This page covers Stem Cell Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Bortezomib page lists 38 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Ashwagandha (moderate) and Black Cohosh (moderate).

By severity: 3 major · 35 moderate.

From our pharmacist’s overview on the Bortezomib page

“Someone on bortezomib (Velcade) for multiple myeloma is often also reaching for herbal products to hold up through chemotherapy, and that is exactly where this list calls for real care. Of the 38 ingredients on file, three rate major, and every one of them threatens the liver: Siberian cocklebur, tied to cases of outright liver failure…”

Reviewed by 2 · Jul 18, 2026

Open the Bortezomib interaction page

How much people look this up

Where Stem Cell Therapy and Bortezomib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Stem Cell Therapy
Steady interest

#760 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Bortezomib
Steady interest

#2,342 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Stem Cell Therapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Stem Cell Therapy and Bortezomib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Stem Cell Therapy

What is Stem Cell Therapy?

  • Joint and arthritis pain
  • Sports and orthopedic injuries
  • Anti-aging and wellness
  • Blood and immune disorders (proven medical uses)
  • Neurological conditions (experimental)

Stem cell therapy is a medical treatment, not a dietary supplement or herb. While some forms—like bone marrow transplants for blood cancers—are well-established and FDA-approved, most clinics offering stem cell injections for joints, aging, or chronic disease are selling unproven, sometimes risky treatments. Talk to a qualified doctor and be very cautious of clinics making big promises.

Stem cells (from bone marrow, blood, fat tissue, or umbilical cord) · Clinic-administered injections or infusions of cells

An interaction check asks whether these two react with each other — it does not ask whether Stem Cell Therapy is a good idea for someone in your situation. Here is what our Stem Cell Therapy record says about it on its own.

Stem Cell Therapy: dosing

There is no standard over-the-counter dose for stem cell therapy, because it is a medical procedure, not a supplement you buy and take at home. The type of cells, how they are prepared, and how they are given vary widely by treatment and clinic.For approved uses like transplants, dosing is carefully calculated by specialists based on the patient and condition. For unproven clinic treatments, there is no agreed-upon dose, and that lack of standardization is one reason these treatments are hard to judge for safety.Never accept a stem cell treatment based only on marketing.

From our Stem Cell Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Stem Cell Therapy monograph & all interactions
Medication

About Bortezomib

What Is Bortezomib Used For?

Brand name: Velcade

Bortezomib is used to treat two types of cancer in adults: multiple myeloma (a cancer of plasma cells in the bone marrow) and mantle cell lymphoma (a type of non-Hodgkin lymphoma). These indications are shared across the available products — Velcade, Boruzu, and generic bortezomib formulations.

Velcade, Boruzu, and bortezomib injections are all approved for both conditions. Your care team will determine which product and treatment plan is right for your situation.

Most-Reported Side Effects for Bortezomib

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Plasma cell myeloma 9,117 reports
Neuropathy peripheral 6,473 reports
Diarrhea 5,186 reports
Fatigue 4,550 reports
Pneumonia 4,074 reports
See full Bortezomib drug information
Keep checking

Other Drugs & Stem Cell Therapy

Browse every other medication we’ve checked against Stem Cell Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Stem Cell Therapy References

The 26 references that drive our Stem Cell Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Ansari ZA, Kuriyan AE, Albini TA. Unproven stem cell therapy for macular degeneration. Oncotarget. 2017;8(53):90636-90637. PubMed
  2. Bauer G, Elsallab M, Abou-El-Enein M. Concise Review: A Comprehensive Analysis of Reported Adverse Events in Patients Receiving Unproven Stem Cell-Based Interventions. Stem Cells Transl Med. 2018;7(9):676-685. PubMed
  3. Berkowitz AL, Miller MB, Mir SA, et al. Glioproliferative Lesion of the Spinal Cord as a Complication of "Stem-Cell Tourism". N Engl J Med. 2016 Jul 14;375(2):196-8. PubMed
  4. Kuriyan AE, Albini TA, Townsend JH, et al. Vision Loss after Intravitreal Injection of Autologous "Stem Cells" for AMD. N Engl J Med. 2017;376(11):1047-1053. PubMed
  5. Perkins KM, Spoto S, Rankin DA, et al. Notes from the Field: Infections After Receipt of Bacterially Contaminated Umbilical Cord Blood-Derived Stem Cell Products for Other Than Hematopoietic or Immunologic Reconstitution - United States, 2018. MMWR Morb M
  6. Iijima H, Isho T, Kuroki, Takahashi, Aoyama. Effectiveness of mesenchymal stem cells for treating patients with knee osteoarthritis: a meta-analysis toward the establishment of effective regenerative rehabilitation. NPJ Regen Med. 2018;3:15. PubMed
  7. Sanapati J, Manchikanti L, Atluri S, et al. Do Regenerative Medicine Therapies Provide Long-Term Relief in Chronic Low Back Pain: A Systematic Review and Metaanalysis. Pain Physician. 2018;21(6):515-540. DOI
  8. Rocco M, Juri C. Is treatment with stem cells effective in Parkinson's disease? Medwave. 2018;18(5):e7242. PubMed
  9. Shah R, Latham SB, Khan SA, Shahreyar M, Hwang I, Jovin IS. A comprehensive meta-analysis of stem cell therapy for chronic angina. Clin Cardiol. 2018;41(4):525-531. PubMed
  10. Guo J, Dardik A, Fang K, Huang R, Gu Y. Meta-analysis on the treatment of diabetic foot ulcers with autologous stem cells. Stem Cell Res Ther. 2017;8(1):228. PubMed
  11. Nagpal A, Choy FC, Howell S, et al. Safety and effectiveness of stem cell therapies in early-phase clinical trials in stroke: a systematic review and meta-analysis. Stem Cell Res Ther. 2017;8(1):191. PubMed
  12. Qiu Y, Li MY, Feng T, et al. Systematic review with meta-analysis: the efficacy and safety of stem cell therapy for Crohn's disease. Stem Cell Res Ther. 2017;8(1):136. PubMed
  13. Sormani MP, Muraro PA, Schiavetti I, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis: A meta-analysis. Neurology. 2017;88(22):2115-2122. PubMed
  14. Gao W, Chen D, Liu G, Ran X. Autologous stem cell therapy for peripheral arterial disease: a systematic review and meta-analysis of randomized controlled trials. Stem Cell Res Ther. 2019;10(1):140. PubMed
  15. Fisher SA, Doree C, Mathur A, Taggart DP, Martin-Rendon E. Stem cell therapy for chronic ischaemic heart disease and congestive heart failure. Cochrane Database Syst Rev. 2016;12:CD007888. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Stem Cell Therapy While Taking Bortezomib: Common Questions

Is it safe to have Stem Cell Therapy while taking Bortezomib?
We do not list a known interaction between Stem Cell Therapy and Bortezomib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Stem Cell Therapy and Bortezomib have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Bortezomib interact with any supplements?
Yes. Bortezomib has documented interactions with 38 supplements in our database — Stem Cell Therapy is not one of them. The Bortezomib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Bortezomib and Stem Cell Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.