Sulbutiamine + Alectinib Hydrochloride
Alectinib Hydrochloride brand name: Alecensa.
We found no known interaction between Sulbutiamine and Alectinib Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Alectinib Hydrochloride states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Sulbutiamine and Alectinib Hydrochloride
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Alectinib Hydrochloride and Sulbutiamine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Sulbutiamine at all — not against Alectinib Hydrochloride, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Sulbutiamine safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Alectinib Hydrochloride Products Have a Food Rule — Sulbutiamine Should Not Break It
At least one FDA label for a product containing Alectinib Hydrochloride says to take it with food. If you take Sulbutiamine on an empty stomach out of habit, keep them separate — and take Alectinib Hydrochloride with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Alectinib Hydrochloride products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Administer ALECENSA with food.
From the Dosage and Administration section of the FDA label we read for Alectinib Hydrochloride — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Alectinib Hydrochloride
This page covers Sulbutiamine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Alectinib Hydrochloride page lists 74 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Alfalfa (moderate).
By severity: 4 major · 60 moderate · 10 minor.
From our pharmacist’s overview on the Alectinib Hydrochloride page
“Alectinib (Alecensa) treats ALK-positive lung cancer, and because your liver already has to tolerate this drug, check this page before adding any supplement, not after. Of the 74 ingredients on file, 38 can add stress to the liver, and three of the four major-rated entries (beer, wine, and Siberian cocklebur) are the clearest examples…”
Reviewed by 2 · Jul 18, 2026
Taking Sulbutiamine as Part of a Dietary Supplement Product? Check It for Interactions
We hold 64 real supplement products containing Sulbutiamine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Sulbutiamine. Even though Sulbutiamine itself has no known interaction with Alectinib Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Sulbutiamine and Alectinib Hydrochloride Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#554 of 1,452 supplements looked up here in the last 7 days
#2,135 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Sulbutiamine reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Sulbutiamine and Alectinib Hydrochloride records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Sulbutiamine
What is Sulbutiamine?
- Fatigue and low energy
- Memory and focus
- Mental clarity
- Mood support
- Vitamin B1 deficiency support
Sulbutiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) developed in Japan, often taken for fatigue and to support mental energy and focus. Human evidence is limited and mostly older or small, so its real benefits are uncertain. It is generally well tolerated short-term, but you should talk with a pharmacist or doctor before using it, especially if you have a health condition.
Synthetic compound (not from a plant) · Tablets, capsules
An interaction check asks whether these two react with each other — it does not ask whether Sulbutiamine is a good idea for someone in your situation. Here is what our Sulbutiamine record says about it on its own.
Sulbutiamine: dosing
There is no firmly established standard dose for sulbutiamine as a supplement. Amounts used in older studies and on product labels vary, and there is not enough strong evidence to recommend one clear dose.The safest approach is to follow the directions on the product label and not take more than suggested.
From our Sulbutiamine monograph — the full record covers uses, side effects and every documented interaction.
About Alectinib
What Is Alectinib Used For?
Brand name: Alecensa
Alecensa (alectinib) is used in adults with non-small cell lung cancer (NSCLC) whose tumors have a specific genetic change called ALK-positive (anaplastic lymphoma kinase-positive), confirmed by an FDA-approved test.
Alecensa is used in two situations: as adjuvant treatment — meaning after surgical removal of the tumor — in patients whose tumors were at least 4 cm or had spread to nearby lymph nodes; and as treatment for metastatic NSCLC, meaning cancer that has spread to other parts of the body.
Most-Reported Side Effects for Alectinib Hydrochloride
From FAERS, the FDA’s public side-effect reporting system (7,249 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Sulbutiamine
Browse every other medication we’ve checked against Sulbutiamine — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Sulbutiamine against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Metoprolol ›
- Rivaroxaban ›
- Aspirin ›
- Acetaminophen ›
- Rosuvastatin ›
- Escitalopram ›
- Abemaciclib ›
- Clopidogrel ›
- Tadalafil ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Semaglutide ›
- Warfarin Sodium ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Metformin ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Amitriptyline ›
- Methotrexate ›
- Bendamustine ›
- Acyclovir ›
- Doxycycline ›
- Fluoxetine ›
- Amphetamine ›
- Pregabalin ›
- Lamotrigine ›
- Azithromycin ›
- Acetaminophen, Codeine ›
- Isotretinoin ›
- Gabapentin ›
- Dextroamphetamine ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Clonazepam ›
- Omeprazole ›
- Quetiapine ›
- Letrozole ›
- Duloxetine ›
- Naproxen ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Sulbutiamine list.
Sulbutiamine References
The 4 references that drive our Sulbutiamine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Shah S. Adjuvant role of vitamin B analogue (sulbutiamine) with anti-infective treatment in infection associated asthenia. J Assoc Physicians India. 2003;51:891-5.
- Loo H, Poirier M, Ollat H, et al. [Effects of subutiamine (Arcalion 200) on psycho-behavioral inhibition in major depressive episodes]. Encephale. 2000;26(2):70-5.
- Kiew K, Wan Mohamad W, Ridzuan A, et al. Effects of sulbutiamine on diabetic polyneuropathy: an open randomized controlled study in type 2 diabetics. Malays J Med Sci. 2002;9(1):21-7.
- Sevim S, Kaleagasi H, Tasdelen B. Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. Mult Scler Relat Disord. 2017;16:40-43. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Sulbutiamine and Alectinib Hydrochloride Together: Common Questions
Is it safe to take Sulbutiamine with Alectinib Hydrochloride?
Do Sulbutiamine and Alectinib Hydrochloride have any of the same side effects?
Should I take Sulbutiamine and Alectinib Hydrochloride at the same time of day?
Does Alectinib Hydrochloride interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.