Drug & supplement interaction

Sweet Violet + Darunavir

Darunavir brand name: Prezista.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Sweet Violet and Darunavir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Darunavir states a food rule worth keeping to.

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Interaction report

Sweet Violet and Darunavir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Darunavir and Sweet Violet in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Sweet Violet at all — not against Darunavir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Sweet Violet safety at a glance

Sweet Violet overall Use caution Generally regarded as gentle in small culinary or tea amounts, but human safety data are limited.
Pregnancy Avoid Not enough safety information is available, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough information to know if it is safe while breastfeeding, so avoid it.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Darunavir and Sweet Violet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Darunavir’s Own FDA Label Lists

This is not an interaction — none of it involves Sweet Violet. These are the most notable effects listed in the ADVERSE REACTIONS section of Darunavir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 9 of them are worth acting on rather than waiting out — marked below.

  • Severe muscle breakdown Worth acting on
  • Pancreatitis Worth acting on
  • High blood sugar Worth acting on
  • A severe skin reaction Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Vivid dreams or nightmares

Showing the 10 most notable of 22 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Darunavir. Read the label on DailyMed › Where a percentage is shown, it is the share of 19,043 voluntary FDA FAERS reports for Darunavir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Sweet Violet’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Sweet Violet side to compare — that is a limit of the record, not a statement that Sweet Violet has no side effects.

How to take them

Some Darunavir Products Have a Food Rule — Sweet Violet Should Not Break It

At least one FDA label for a product containing Darunavir says to take it with food. If you take Sweet Violet on an empty stomach out of habit, keep them separate — and take Darunavir with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Darunavir products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.1 , 2.2 , 5.2 ) Treatment-naïve adult patients and treatment-experienced adult patients with no darunavir resistance associated substitutions: 800 mg (one 800 mg tablet) taken with ritonavir 100 mg once daily and with food.

From the Dosage and Administration section of the FDA label we read for Darunavir — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Sweet Violet or Darunavir

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Sweet Violet or Darunavir, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Darunavir

This page covers Sweet Violet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Darunavir page lists 145 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 102 moderate · 40 minor.

From our pharmacist’s overview on the Darunavir page

“Someone on darunavir (Prezista) for HIV depends on steady drug levels to keep the virus suppressed, and this list of 145 interacting supplements calls for real caution before adding any of them. Most of the traffic runs through the CYP3A4 enzyme, in both directions.”

Reviewed by 2 · Jul 18, 2026

Open the Darunavir interaction page

One more smart check

Taking Sweet Violet as Part of a Dietary Supplement Product? Check It for Interactions

We hold 14 real supplement products containing Sweet Violet, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Sweet Violet. Even though Sweet Violet itself has no known interaction with Darunavir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Sweet Violet and Darunavir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Sweet Violet
Steady interest

#1,178 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Darunavir
Steady interest

#2,016 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Sweet Violet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Sweet Violet and Darunavir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Sweet Violet

What is Sweet Violet?

  • Cough and sore throat
  • Bronchitis and chest congestion
  • Trouble sleeping
  • Skin irritation
  • Mild constipation
  • Headache

Sweet Violet is a traditional herb used mainly as a soothing remedy for coughs, sore throats, and minor respiratory complaints. Modern scientific evidence supporting these uses is very limited, so it should not replace proven treatments. It is generally considered gentle in food-like amounts, but talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or giving it to a child.

Viola odorata · Violaceae · Flowers, leaves, and roots; sometimes the whole plant · Tea (infusion), syrup, dried herb, tincture, and topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Sweet Violet is a good idea for someone in your situation. Here is what our Sweet Violet record says about it on its own.

Sweet Violet: dosing

There is no standardized or officially established dose for Sweet Violet. Traditional use most often involves a tea made from the dried flowers or leaves, or a syrup for cough, but exact amounts vary widely between products and recipes.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Sweet Violet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Sweet Violet monograph & all interactions
Medication

About Darunavir

What Is Darunavir Used For?

Brand name: Prezista

Darunavir treats HIV-1 infection in adults and in children who are at least 3 years old and weigh at least 10 kg (about 22 lbs). It is not a cure for HIV, but it is used as part of a combination antiretroviral regimen to control the virus.

Darunavir must always be taken together with ritonavir — that pairing is required for darunavir to work properly. Both Prezista (brand name) and generic darunavir tablets are approved for this use. Prezista is also available as an oral suspension, which is particularly useful for younger or smaller patients.

Most-Reported Side Effects for Darunavir

From FAERS, the FDA’s public side-effect reporting system (19,043 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Bone density decreased 1,418 reports
Emotional distress 1,271 reports
Anxiety 1,260 reports
Chronic kidney disease 1,222 reports
Foetal exposure during pregnancy 1,221 reports
See full Darunavir drug information
Keep checking

Other Drugs & Sweet Violet

Browse every other medication we’ve checked against Sweet Violet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Sweet Violet References

The 8 references that drive our Sweet Violet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Beiraghdar F, Einollahi B, Ghadyani A, et al. A two-week, double-blind, placebo-controlled trial of Viola odorata, Echium amoenum and Physalis alkekengi mixture in symptomatic benign prostate hyperplasia (BPH) men. Pharm Biol 2017;55(1):1800-5.
  2. Qasemzadeh MJ, Sharifi H, Hamedanian M, et al. The effect of Viola odorata flower syrup on the cough of children with asthma: a double-blind, randomized controlled trial. J Evid Based Complementary Altern Med 2015;20(4):287-91. doi: 10.1177/21565872155848 PubMed
  3. Feyzabadi Z, Rezaeitalab F, Badiee S, et al. Efficacy of Violet oil, a traditional Iranian formula, in patients with chronic insomnia: A randomized, double-blind, placebo-controlled study. J Ethnopharmacol 2018;214:22-8. doi: 10.1016/j.jep.2017.11.036. PubMed
  4. Shayesteh M, Vaez-Mahdavi MR, Shams J, et al. Effects of Viola odorata as an Add-On Therapy on Insomnia in Patients with Obsession or Depression: A Pilot Randomized Double-Blind Placebo-Controlled Trial. J Altern Complement Med 2020;26(5):398-408.
  5. Taherzadeh Z, Khaluyan H, Iranshahy M, Rezaeitalab F, Eshaghi Ghalibaf MH, Javadi B. Evaluation of sedative effects of an intranasal dosage form containing saffron, lettuce seeds and sweet violet in primary chronic insomnia: A randomized, double-dummy, do
  6. Tafazoli V, Shahriari M, Heydari M, Nikbakht HA, Zarshenaas MM, Nimrouzi M. The Effect of Viola Odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial. Curr Drug Discov Technol 2020;17(5):696-703. PubMed
  7. Yazdi N, Kardooni M, Namjuyan F, Vardanjani HM, Tafazoli V, Jaladat AM. Efficacy of Sweet Violet (Viola odorata) flower oil on the symptoms of adults with allergic rhinitis: A double-blind randomized placebo-controlled clinical trial. Complement Ther Med PubMed
  8. Saffar Shahroodi A, Nejabat M, Nimrouzi M, Aghaei H, Salehi A, Rezaei Mokarram A. Effects of intranasal administration of violet oil in dry eye disease. Clin Exp Optom 2019;102(6):576-582. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Sweet Violet and Darunavir Together: Common Questions

Is it safe to take Sweet Violet with Darunavir?
We do not list a known interaction between Sweet Violet and Darunavir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Sweet Violet and Darunavir at the same time of day?
At least one FDA label for a product containing Darunavir says to take it with food. If you take Sweet Violet on an empty stomach out of habit, keep them separate and take Darunavir with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Darunavir products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Darunavir interact with any supplements?
Yes. Darunavir has documented interactions with 145 supplements in our database — Sweet Violet is not one of them. The Darunavir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Darunavir and Sweet Violet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.