Sweet Violet + Lamotrigine
Lamotrigine brand name: Lamictal.
We found no known interaction between Sweet Violet and Lamotrigine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Sweet Violet and Lamotrigine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Lamotrigine and Sweet Violet in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Sweet Violet at all — not against Lamotrigine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Sweet Violet safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
What Lamotrigine Is Prescribed For, and What Sweet Violet Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Lamotrigine is a prescription medicine with approved uses on its FDA label. Sweet Violet is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Lamotrigine is prescribed for: Lamotrigine is used to treat several types of seizures in adults and children aged 2 and older — including partial-onset seizures, generalized tonic-clonic (grand mal) seizures, and seizures related to Lennox-Gastaut syndrome. In older teens and adults, it can also be used alone (monotherapy) after transitioning off another seizure medicine. For adults with bipolar I disorder, lamotrigine is used as a maintenance treatment — meaning it helps delay the return of mood episodes like depression, mania, or mixed states. It is not approved to treat an active manic or mixed episode that's happening right now.
Sweet Violet has been studied for:
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Depression studied, not established Sweet Violet has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Sweet Violet for depression
A small study in patients aged 16 to 50 years with mild to moderate depression and insomnia who are taking sertraline shows that taking an extract of sweet violet aerial parts syrup every 12 hours for 4 weeks improves Pittsburgh Sleep Quality Index (PSQI) scores by 10 points, compared with 3 points in those receiving placebo.
1 source cited
- 106575. Shayesteh M, Vaez-Mahdavi MR, Shams J, et al. Effects of Viola odorata as an Add-On Therapy on Insomnia in Patients with Obsession or Depression: A Pilot Randomized Double-Blind Placebo-Controlled Trial. J Altern Complement Med 2020;26(5):398-408.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Lamotrigine on your own; if you are taking Sweet Violet for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Sweet Violet or Lamotrigine
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Sweet Violet or Lamotrigine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Avantera Elevate Drug Interaction Concerns ›
- Accidentally Took Two Seroquel During The Day Instead Of One ›
- Is Dandelion Safe With Gabapentin And Lamotrigine? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Lamotrigine
This page covers Sweet Violet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lamotrigine page lists 116 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).
By severity: 7 major · 92 moderate · 17 minor.
From our pharmacist’s overview on the Lamotrigine page
“Alcohol, ordinary beer or wine, sits at the top of the interaction list for lamotrigine (Lamictal), with well-documented added sedation, and it sets the tone for a list I would treat with real care. Of the 116 supplements and herbs on file, 78 have sedative effects of their own, so the biggest theme by far is stacked drowsiness and slo…”
Reviewed by 2 · Jul 18, 2026
Taking Sweet Violet as Part of a Dietary Supplement Product? Check It for Interactions
We hold 14 real supplement products containing Sweet Violet, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Sweet Violet. Even though Sweet Violet itself has no known interaction with Lamotrigine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Sweet Violet and Lamotrigine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,420 of 1,452 supplements looked up here in the last 7 days
#32 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Sweet Violet reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Sweet Violet and Lamotrigine records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Sweet Violet
What is Sweet Violet?
- Cough and sore throat
- Bronchitis and chest congestion
- Trouble sleeping
- Skin irritation
- Mild constipation
- Headache
Sweet Violet is a traditional herb used mainly as a soothing remedy for coughs, sore throats, and minor respiratory complaints. Modern scientific evidence supporting these uses is very limited, so it should not replace proven treatments. It is generally considered gentle in food-like amounts, but talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or giving it to a child.
Viola odorata · Violaceae · Flowers, leaves, and roots; sometimes the whole plant · Tea (infusion), syrup, dried herb, tincture, and topical preparations
An interaction check asks whether these two react with each other — it does not ask whether Sweet Violet is a good idea for someone in your situation. Here is what our Sweet Violet record says about it on its own.
Sweet Violet: dosing
There is no standardized or officially established dose for Sweet Violet. Traditional use most often involves a tea made from the dried flowers or leaves, or a syrup for cough, but exact amounts vary widely between products and recipes.The safest approach is to follow the directions on the product label and not exceed the recommended amount.
From our Sweet Violet monograph — the full record covers uses, side effects and every documented interaction.
About Lamotrigine
What Is Lamotrigine Used For?
Brand name: Lamictal
Lamotrigine is used to treat several types of seizures in adults and children aged 2 and older — including partial-onset seizures, generalized tonic-clonic (grand mal) seizures, and seizures related to Lennox-Gastaut syndrome. In older teens and adults, it can also be used alone (monotherapy) after transitioning off another seizure medicine.
For adults with bipolar I disorder, lamotrigine is used as a maintenance treatment — meaning it helps delay the return of mood episodes like depression, mania, or mixed states. It is not approved to treat an active manic or mixed episode that's happening right now.
Other Drugs & Sweet Violet
Browse every other medication we’ve checked against Sweet Violet — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Sweet Violet against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Ibuprofen ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Sweet Violet list.
Sweet Violet References
The 8 references that drive our Sweet Violet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Beiraghdar F, Einollahi B, Ghadyani A, et al. A two-week, double-blind, placebo-controlled trial of Viola odorata, Echium amoenum and Physalis alkekengi mixture in symptomatic benign prostate hyperplasia (BPH) men. Pharm Biol 2017;55(1):1800-5.
- Qasemzadeh MJ, Sharifi H, Hamedanian M, et al. The effect of Viola odorata flower syrup on the cough of children with asthma: a double-blind, randomized controlled trial. J Evid Based Complementary Altern Med 2015;20(4):287-91. doi: 10.1177/21565872155848 PubMed
- Feyzabadi Z, Rezaeitalab F, Badiee S, et al. Efficacy of Violet oil, a traditional Iranian formula, in patients with chronic insomnia: A randomized, double-blind, placebo-controlled study. J Ethnopharmacol 2018;214:22-8. doi: 10.1016/j.jep.2017.11.036. PubMed
- Shayesteh M, Vaez-Mahdavi MR, Shams J, et al. Effects of Viola odorata as an Add-On Therapy on Insomnia in Patients with Obsession or Depression: A Pilot Randomized Double-Blind Placebo-Controlled Trial. J Altern Complement Med 2020;26(5):398-408.
- Taherzadeh Z, Khaluyan H, Iranshahy M, Rezaeitalab F, Eshaghi Ghalibaf MH, Javadi B. Evaluation of sedative effects of an intranasal dosage form containing saffron, lettuce seeds and sweet violet in primary chronic insomnia: A randomized, double-dummy, do
- Tafazoli V, Shahriari M, Heydari M, Nikbakht HA, Zarshenaas MM, Nimrouzi M. The Effect of Viola Odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial. Curr Drug Discov Technol 2020;17(5):696-703. PubMed
- Yazdi N, Kardooni M, Namjuyan F, Vardanjani HM, Tafazoli V, Jaladat AM. Efficacy of Sweet Violet (Viola odorata) flower oil on the symptoms of adults with allergic rhinitis: A double-blind randomized placebo-controlled clinical trial. Complement Ther Med PubMed
- Saffar Shahroodi A, Nejabat M, Nimrouzi M, Aghaei H, Salehi A, Rezaei Mokarram A. Effects of intranasal administration of violet oil in dry eye disease. Clin Exp Optom 2019;102(6):576-582. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Lamotrigine Is Linked to Lower Levels of One Nutrient
Natural Medicines records Lamotrigine as a medicine that can lower these. This is not an interaction with Sweet Violet — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Lamotrigine nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Sweet Violet and Lamotrigine Together: Common Questions
Is it safe to take Sweet Violet with Lamotrigine?
Are Sweet Violet and Lamotrigine used for the same thing?
Does Lamotrigine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Lamotrigine and Sweet Violet?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.