Drug & supplement interaction

Tagetes + Cefaclor

Cefaclor brand names: Ceclor CD, Ceclor.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Tagetes and Cefaclor in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Cefaclor states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Tagetes and Cefaclor

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cefaclor and Tagetes in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Tagetes at all — not against Cefaclor, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tagetes safety at a glance

Tagetes overall Use caution Generally considered low-risk in food amounts, but the essential oil and concentrated extracts can irritate skin and lack strong safety data.
Pregnancy Avoid Avoid medicinal or essential oil use during pregnancy because safety has not been established.
Breastfeeding Avoid Not enough safety information exists, so avoid medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cefaclor and Tagetes? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Tagetes and Cefaclor May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Tagetes

    “Topically, ornamental marigold has been reported to cause contact dermatitis (11).”

    Tagetes · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 11. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

Effects for Cefaclor come from the ADVERSE REACTIONS section of its FDA label; effects for Tagetes come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Cefaclor Products Have a Food Rule — Tagetes Should Not Break It

At least one FDA label for a product containing Cefaclor says to take it with food. If you take Tagetes on an empty stomach out of habit, keep them separate — and take Cefaclor with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Cefaclor products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

DOSAGE AND ADMINISTRATION The absorption of cefaclor extended-release tablets is enhanced when it is administered with food.

From the Dosage and Administration section of the FDA label we read for Cefaclor — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Cefaclor

This page covers Tagetes only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cefaclor page lists 60 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).

By severity: 3 major · 46 moderate · 11 minor.

From our pharmacist’s overview on the Cefaclor page

“The entries worth understanding before any others on this cefaclor (Ceclor) page are the kidney risks and charcoal. Cefaclor is a cephalosporin antibiotic, typically a short course for ear, sinus, throat, or skin infections, and two herbs here, Siberian cocklebur and asarabacca, can damage the kidneys on their own, so pairing either wi…”

Reviewed by 2 · Jul 18, 2026

Open the Cefaclor interaction page

One more smart check

Taking Tagetes as Part of a Dietary Supplement Product? Check It for Interactions

We hold 100 real supplement products containing Tagetes, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tagetes. Even though Tagetes itself has no known interaction with Cefaclor, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tagetes and Cefaclor Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tagetes
Top half

#668 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cefaclor
Top 10%

#260 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tagetes reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Tagetes and Cefaclor records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tagetes

What is Tagetes?

  • Digestive upset
  • Antimicrobial and antifungal
  • Skin and wound care
  • Insect repellent
  • Eye health (lutein source from petals)

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most health benefits is very limited, and the essential oil can cause skin reactions and sun sensitivity. Talk to a pharmacist or doctor before using it, especially while pregnant or breastfeeding.

Asteraceae · Flowers, leaves, and essential oil · Essential oil, tea, dried flowers, topical preparations, tinctures

An interaction check asks whether these two react with each other — it does not ask whether Tagetes is a good idea for someone in your situation. Here is what our Tagetes record says about it on its own.

Tagetes: dosing

There is no well-established standard dose for Tagetes as a supplement or medicine. Products vary widely in strength, and the amount of active compounds depends on the species, plant part, and how it was prepared.If you choose to use a Tagetes product, follow the directions on the label and do not exceed them. Essential oils should be diluted before any skin use and kept away from the eyes and mouth.

From our Tagetes monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tagetes monograph & all interactions
Medication

About Cefaclor

What Is Cefaclor Used For?

Brand names: Ceclor CD, Ceclor

Cefaclor treats a range of bacterial infections. The capsule and oral suspension forms are used for ear infections (otitis media), lower respiratory tract infections including pneumonia, strep throat and tonsillitis, urinary tract infections (including kidney infections and bladder infections), and skin and skin structure infections.

The extended-release tablet form of Cefaclor is approved for a narrower set of uses: acute bacterial flare-ups of chronic bronchitis, strep throat and tonsillitis, and uncomplicated skin infections. Not all infections approved for the capsule or suspension are approved for the extended-release tablet — your prescriber will choose the right form for your infection.

Most-Reported Side Effects for Cefaclor

From FAERS, the FDA’s public side-effect reporting system (1,535 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Drug hypersensitivity 252 reports
Nausea 159 reports
Vomiting 159 reports
Fatigue 137 reports
Fever 121 reports
See full Cefaclor drug information
Keep checking

Other Drugs & Tagetes

Browse every other medication we’ve checked against Tagetes — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Tagetes against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tagetes list.

See the full Tagetes interactions page
See every supplement checked against Cefaclor, ranked by severity
Evidence & sources

Tagetes References

The 1 references that drive our Tagetes monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tagetes and Cefaclor Together: Common Questions

Is it safe to take Tagetes with Cefaclor?
We do not list a known interaction between Tagetes and Cefaclor. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Tagetes and Cefaclor have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Tagetes and Cefaclor at the same time of day?
At least one FDA label for a product containing Cefaclor says to take it with food. If you take Tagetes on an empty stomach out of habit, keep them separate and take Cefaclor with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Cefaclor products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Cefaclor interact with any supplements?
Yes. Cefaclor has documented interactions with 60 supplements in our database — Tagetes is not one of them. The Cefaclor interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tagetes monograph Uses, safety profile, and every drug interaction in one place Cefaclor drug information The full plain-English guide to this medication Cefaclor supplement interactions Every supplement checked against Cefaclor, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Cefaclor and Tagetes?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.