Drug & supplement interaction

Tagetes + Trospium

Trospium brand names: Sanctura, Trosec, Regurin.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Tagetes and Trospium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Trospium states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Tagetes and Trospium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Trospium and Tagetes in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Tagetes at all — not against Trospium, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tagetes safety at a glance

Tagetes overall Use caution Generally considered low-risk in food amounts, but the essential oil and concentrated extracts can irritate skin and lack strong safety data.
Pregnancy Avoid Avoid medicinal or essential oil use during pregnancy because safety has not been established.
Breastfeeding Avoid Not enough safety information exists, so avoid medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Trospium and Tagetes? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Tagetes and Trospium May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Tagetes

    “Topically, ornamental marigold has been reported to cause contact dermatitis (11).”

    Tagetes · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 11. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

    Trospium

    Listed in the ADVERSE REACTIONS section of the FDA label for Trospium. Read the label on DailyMed ›

Effects for Trospium come from the ADVERSE REACTIONS section of its FDA label; effects for Tagetes come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Trospium Products Have a Food Rule — Tagetes Should Not Break It

At least one FDA label for a product containing Trospium says to take it on an empty stomach. Most supplements — Tagetes included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Trospium on its own and move Tagetes to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Trospium products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Trospium Chloride Extended-Release Capsules should be dosed with water on an empty stomach, at least one hour before a meal.

From the Dosage and Administration section of the FDA label we read for Trospium — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Trospium

This page covers Tagetes only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Trospium page lists 47 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), Angel's Trumpet (moderate) and Bacopa (moderate).

By severity: 3 major · 33 moderate · 11 minor.

From our pharmacist’s overview on the Trospium page

“Trospium (Sanctura, Regurin) calms an overactive bladder by blocking acetylcholine, and most of the 47 supplements flagged against it press on that same nerve signal. Thirty carry anticholinergic activity of their own, adding dry mouth, constipation, blurred vision, and confusion, and two of the three major ratings sit in that group: h…”

Reviewed by 2 · Jul 18, 2026

Open the Trospium interaction page

One more smart check

Taking Tagetes as Part of a Dietary Supplement Product? Check It for Interactions

We hold 100 real supplement products containing Tagetes, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tagetes. Even though Tagetes itself has no known interaction with Trospium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tagetes and Trospium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tagetes
Steady interest

#741 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Trospium
Steady interest

#1,843 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tagetes reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Tagetes and Trospium records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tagetes

What is Tagetes?

  • Digestive upset
  • Antimicrobial and antifungal
  • Skin and wound care
  • Insect repellent
  • Eye health (lutein source from petals)

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most health benefits is very limited, and the essential oil can cause skin reactions and sun sensitivity. Talk to a pharmacist or doctor before using it, especially while pregnant or breastfeeding.

Asteraceae · Flowers, leaves, and essential oil · Essential oil, tea, dried flowers, topical preparations, tinctures

An interaction check asks whether these two react with each other — it does not ask whether Tagetes is a good idea for someone in your situation. Here is what our Tagetes record says about it on its own.

Tagetes: dosing

There is no well-established standard dose for Tagetes as a supplement or medicine. Products vary widely in strength, and the amount of active compounds depends on the species, plant part, and how it was prepared.If you choose to use a Tagetes product, follow the directions on the label and do not exceed them. Essential oils should be diluted before any skin use and kept away from the eyes and mouth.

From our Tagetes monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tagetes monograph & all interactions
Medication

About Trospium

What Is Trospium Used For?

Brand names: Sanctura, Trosec, Regurin

Trospium — available as tablets and extended-release capsules — is used to treat overactive bladder (OAB). It targets three main symptoms: the sudden, hard-to-control urge to urinate (urgency), leaking urine when that urge hits (urge urinary incontinence), and needing to urinate much more often than usual (urinary frequency).

Both Trospium Chloride Tablets and Trospium Chloride Extended-Release Capsules carry this indication. Your prescriber will choose the formulation that fits your schedule and health history.

See full Trospium drug information
Keep checking

Other Drugs & Tagetes

Browse every other medication we’ve checked against Tagetes — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Tagetes against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tagetes list.

See the full Tagetes interactions page
See every supplement checked against Trospium, ranked by severity
Evidence & sources

Tagetes References

The 1 references that drive our Tagetes monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tagetes and Trospium Together: Common Questions

Is it safe to take Tagetes with Trospium?
We do not list a known interaction between Tagetes and Trospium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Tagetes and Trospium have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Tagetes and Trospium at the same time of day?
At least one FDA label for a product containing Trospium says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Trospium on its own and move Tagetes to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Trospium interact with any supplements?
Yes. Trospium has documented interactions with 47 supplements in our database — Tagetes is not one of them. The Trospium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tagetes monograph Uses, safety profile, and every drug interaction in one place Trospium drug information The full plain-English guide to this medication Trospium supplement interactions Every supplement checked against Trospium, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Trospium and Tagetes?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.