Drug & supplement interaction

Tamarix Dioica + Riociguat

Riociguat brand name: Adempas.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Tamarix Dioica and Riociguat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Tamarix Dioica and Riociguat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Riociguat and Tamarix Dioica in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Tamarix Dioica at all — not against Riociguat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tamarix Dioica safety at a glance

Tamarix Dioica overall Not established Human safety data are very limited, so caution is advised.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety during breastfeeding is unknown, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Riociguat and Tamarix Dioica? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Riociguat’s Own FDA Label Lists

This is not an interaction — none of it involves Tamarix Dioica. These are the most notable effects listed in the ADVERSE REACTIONS section of Riociguat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 3 of them are worth acting on rather than waiting out — marked below.

  • Trouble swallowing Worth acting on
  • Anemia Worth acting on
  • Bleeding or bruising Worth acting on
  • Heartburn
  • Bloating or gas
  • A stuffy or runny nose
  • A fast or pounding heartbeat
  • Low blood pressure
  • Stomach upset
  • Constipation

Showing the 10 most notable of 16 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Riociguat. Read the label on DailyMed › Tamarix Dioica’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Tamarix Dioica side to compare — that is a limit of the record, not a statement that Tamarix Dioica has no side effects.

Everything else you take

See Every Supplement That Interacts With Riociguat

This page covers Tamarix Dioica only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Riociguat page lists 230 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Grapefruit (major) and St. John's Wort (major).

By severity: 6 major · 187 moderate · 37 minor.

From our pharmacist’s overview on the Riociguat page

“Riociguat (Adempas) works by relaxing the blood vessels in your lungs, which also lowers blood pressure, so I read this list of 230 supplements and herbs with real concern, and the six rated major are what to understand first. Grapefruit can push riociguat levels up and intensify its effect, while St.”

Reviewed by 2 · Jul 18, 2026

Open the Riociguat interaction page

How much people look this up

Where Tamarix Dioica and Riociguat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tamarix Dioica
Steady interest

#1,279 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Riociguat
Steady interest

#1,721 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Tamarix Dioica is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tamarix Dioica reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Tamarix Dioica and Riociguat records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tamarix Dioica

What is Tamarix Dioica?

  • Liver and digestive complaints (traditional)
  • Wound healing and skin problems
  • Inflammation and swelling
  • Antimicrobial uses
  • General tonic in folk medicine

Tamarix dioica is a shrub used in traditional South Asian medicine, mostly for liver, digestive, and skin complaints. Scientific evidence in humans is very limited, and most data come from laboratory or animal studies. Because safety has not been well studied, talk with a pharmacist or doctor before using it.

Tamarix dioica · Tamaricaceae · Leaves, bark, flowers, and aerial parts · Crude plant extracts, powders, and traditional decoctions; not widely available as standardized commercial products

An interaction check asks whether these two react with each other — it does not ask whether Tamarix Dioica is a good idea for someone in your situation. Here is what our Tamarix Dioica record says about it on its own.

Tamarix Dioica: dosing

There is no established or standardized dose for Tamarix dioica. Traditional use involved homemade decoctions and crude extracts, which cannot be measured reliably.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Tamarix Dioica monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tamarix Dioica monograph & all interactions
Medication

About Riociguat

What Is Riociguat Used For?

Brand name: Adempas

Riociguat tablets — sold as Adempas and under the generic name Riociguat — are used to treat adults with two types of pulmonary hypertension (high blood pressure in the lungs).

The first is chronic thromboembolic pulmonary hypertension (CTEPH), a condition caused by blood clots in the lung arteries, either after surgery or when surgery is not an option. The second is pulmonary arterial hypertension (PAH), where the arteries carrying blood to the lungs are narrowed or blocked. In both conditions, riociguat helps improve exercise ability and functional status, and in PAH it also helps slow the disease from getting worse.

Most-Reported Side Effects for Riociguat

From FAERS, the FDA’s public side-effect reporting system (32,415 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 5,718 reports
Headache 4,513 reports
Nausea 3,769 reports
Diarrhea 3,533 reports
Dizziness 3,522 reports
See full Riociguat drug information
Keep checking

Other Drugs & Tamarix Dioica

Browse every other medication we’ve checked against Tamarix Dioica — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Tamarix Dioica against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tamarix Dioica list.

See the full Tamarix Dioica interactions page
See every supplement checked against Riociguat, ranked by severity
Evidence & sources

Tamarix Dioica References

The 3 sources that drive our Tamarix Dioica monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Tamarix Dioica is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health (NCCIH) Source
  2. Herbal Supplements — MedlinePlus (U.S. National Library of Medicine) Source
  3. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tamarix Dioica and Riociguat Together: Common Questions

Is it safe to take Tamarix Dioica with Riociguat?
We do not list a known interaction between Tamarix Dioica and Riociguat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Riociguat interact with any supplements?
Yes. Riociguat has documented interactions with 230 supplements in our database — Tamarix Dioica is not one of them. The Riociguat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tamarix Dioica monograph Uses, safety profile, and every drug interaction in one place Riociguat drug information The full plain-English guide to this medication Riociguat supplement interactions Every supplement checked against Riociguat, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Riociguat and Tamarix Dioica?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.