Drug & supplement interaction

Tansy + Apixaban

Apixaban brand name: Eliquis.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Tansy and Apixaban in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Tansy and Apixaban

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Apixaban and Tansy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tansy safety at a glance

Tansy overall Avoid Tansy contains thujone, which can be poisonous, so internal use is generally discouraged.
Pregnancy Likely Unsafe When used orally or topically due to potential abortifacient, menstrual flow, and uterine stimulant effects. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally due to thujone content. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Apixaban and Tansy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Apixaban

Interactions in our licensed database are recorded against drug classes, not just single drug names. Apixaban is filed under 4 classifications — including anticoagulant/antiplatelet drugs, p-glycoprotein substrates, cytochrome p450 3a4 (cyp3a4) substrates. Tansy has documented interactions with 1 drug class — the most serious being alcohol (ethanol) (major) — and none of Apixaban’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Tansy Does Interact With Other Medications

Tansy has 1 major, known drug interaction in our database — Apixaban isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Tansy

Covers the 2,830 medications we’ve checked against Tansy. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Tansy and Apixaban May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

  • An irregular heartbeat Worth acting on Additional detail

    Tansy

    “There is limited reliable information available about the adverse effects of tansy. Orally, varieties of tansy that contain the toxic constituent thujone have been reported to cause thujone toxicity. Symptoms of thujone toxicity include rapid pulse, irregular heartbeat, tachypnea, severe gastroenteritis, vomiting, dilated pupils, hepatotoxicity, nephrotoxicity, and death (4,6,77012,77014,77015).”

    Tansy · Natural Medicines adverse-effect record, reported in dermatitis.

    6 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
    3. 77012. McGuffin M and et al. American Herbal Products Association's Botanical Safety Handbook. 1997.
    4. 77014. The Review of Natural Products by Facts and Comparisons. 1999.
    5. 77015. Blumenthal, M and et al. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. 1998;
    6. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Apixaban

    Listed in the ADVERSE REACTIONS section of the FDA label for Apixaban. Read the label on DailyMed ›

  • Bleeding or bruising Worth acting on Additional detail

    Tansy

    “Orally, large doses of tansy have been reported to induce abortion and uterine bleeding.”

    Tansy · Natural Medicines adverse-effect record, reported in abortion.

    1 source cited
    1. 77015. Blumenthal, M and et al. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. 1998;

    Apixaban

    Listed in the ADVERSE REACTIONS section of the FDA label for Apixaban. Read the label on DailyMed ›

Reported for Tansy but not commonly for Apixaban: fainting, sun sensitivity, stomach pain and liver problems.

Effects for Apixaban come from the ADVERSE REACTIONS section of its FDA label; effects for Tansy come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Tansy in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally or topically due to potential abortifacient, menstrual flow, and uterine stimulant effects.

Lactation Likely Unsafe

When used orally due to thujone content.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Tansy or Apixaban

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tansy or Apixaban, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Apixaban

This page covers Tansy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Apixaban page lists 285 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Danshen (major), Grapefruit (major), Piracetam (major) and St. John's Wort (major).

By severity: 5 major · 240 moderate · 40 minor.

From our pharmacist’s overview on the Apixaban page

“St. John's wort can weaken apixaban (Eliquis), speeding how the body clears this blood thinner and leaving you less protected from the strokes and clots it is prescribed to prevent.”

Reviewed by 2 · Jul 18, 2026

Open the Apixaban interaction page

One more smart check

Taking Tansy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 45 real supplement products containing Tansy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tansy. Even though Tansy itself has no known interaction with Apixaban, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tansy and Apixaban Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tansy
Steady interest

#911 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Apixaban
Most looked up

#1 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tansy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Tansy and Apixaban records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tansy

What is Tansy?

  • Intestinal worms and parasites
  • Digestive upset
  • Menstrual problems
  • Insect repellent
  • Skin and wound care (traditional)

Tansy is a traditional bitter herb that contains thujone, a compound that can be toxic in higher amounts. Because of real safety concerns and very limited modern evidence, most people should avoid taking tansy internally, and it should never be used during pregnancy.

Tanacetum vulgare · Asteraceae · Flowers, leaves, and essential oil · Tea, dried herb, tincture, essential oil

An interaction check asks whether these two react with each other — it does not ask whether Tansy is a good idea for someone in your situation. Here is what our Tansy record says about it on its own.

Tansy: dosing

There is no established safe or standardized dose of tansy. Never use the concentrated essential oil internally, and follow all product labels carefully. In most cases, a safer alternative is the better choice.

From our Tansy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tansy monograph & all interactions
Medication

About Apixaban

What Is Apixaban Used For?

Brand name: Eliquis

Apixaban is used to reduce the risk of stroke and dangerous clots traveling through the body in adults with nonvalvular atrial fibrillation (an irregular heart rhythm not caused by a heart valve problem). It is also used to prevent deep vein thrombosis (DVT — a blood clot in the leg) in adults after hip or knee replacement surgery, and to treat DVT and pulmonary embolism (PE — a blood clot in the lungs) in adults, including reducing the risk of those clots coming back.

Eliquis (the brand-name tablet and kit) is additionally approved to treat venous thromboembolism (VTE — blood clots in the veins) and reduce the risk of recurrent VTE in pediatric patients from birth and older, after at least 5 days of initial anticoagulant treatment. The generic apixaban tablet carries the adult indications only.

See full Apixaban drug information
Keep checking

Other Drugs & Tansy

Browse every other medication we’ve checked against Tansy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

1Major
0Moderate
0Minor
2,828No known interaction
Major

1 interaction

No interaction 2,828 drugs checked — show the list
Evidence & sources

Tansy References

The 14 references that drive our Tansy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  6. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  7. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  8. Jovanovic, M. and Poljacki, M. [Compositae dermatitis]. Med Pregl. 2003;56(1-2):43-49. PubMed
  9. Guin, J. D. and Skidmore, G. Compositae dermatitis in childhood. Arch Dermatol. 1987;123(4):500-502. DOI
  10. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  11. Mark, K. A., Brancaccio, R. R., Soter, N. A., and Cohen, D. E. Allergic contact and photoallergic contact dermatitis to plant and pesticide allergens. Arch Dermatol. 1999;135(1):67-70. PubMed
  12. McGuffin M and et al. American Herbal Products Association's Botanical Safety Handbook. 1997.
  13. The Review of Natural Products by Facts and Comparisons. 1999.
  14. Blumenthal, M and et al. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. 1998;

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tansy and Apixaban Together: Common Questions

Is it safe to take Tansy with Apixaban?
We do not list a known interaction between Tansy and Apixaban. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Tansy and Apixaban have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Tansy and Apixaban combination checked?
Interactions in our licensed database are recorded against drug classes. Apixaban is filed under 4 classifications, and Tansy has documented interactions with 1 drug class — none of Apixaban's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Tansy interact with any other medications?
Yes. Tansy has 1 documented drug interaction in our database — Apixaban is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Apixaban interact with any supplements?
Yes. Apixaban has documented interactions with 285 supplements in our database — Tansy is not one of them. The Apixaban interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Apixaban and Tansy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.