Thiamine + Insulin Lispro

Thiamine has 3 minor known drug interactions in our database — Insulin Lispro isn’t one of them. If you take anything else, check it against the full list below.

We haven’t checked that one against Thiamine yet — ask our pharmacists directly.

Covers the 2,830 medications we’ve checked against Thiamine. Pick one to open its full report.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

At least one FDA label for a product containing Insulin Lispro says to take it with food. If you take Thiamine on an empty stomach out of habit, keep them separate — and take Insulin Lispro with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Insulin Lispro products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

These two come up together because they touch the same health topic — not because they do the same job. Insulin Lispro is a prescription medicine with approved uses on its FDA label. Thiamine is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Insulin Lispro is prescribed for: Insulin lispro injection is used to improve glycemic control (blood sugar management) in people with diabetes mellitus. It is a rapid-acting insulin analog approved for use in both type 1 and type 2 diabetes. Admelog is specifically indicated to improve glycemic control in patients with diabetes mellitus. Humalog Mix75/25 is indicated to improve glycemic control in adults with diabetes mellitus; it is a fixed-ratio mixture of insulin lispro and insulin lispro protamine, and its fixed proportions do not allow for separate adjustment of basal (background) and prandial (mealtime) doses.

Thiamine has been studied for:

• Kidney failure studied, not established Thiamine has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

  Thiamine for kidney failure

  Oral thiamine has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

• Diabetes studied, not established Thiamine has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

  Thiamine for diabetes

  It is unclear if oral thiamine is beneficial for type 2 diabetes or gestational diabetes.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Insulin Lispro on your own; if you are taking Thiamine for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

This page covers Thiamine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Insulin Lispro page lists 239 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate), Agaricus Mushroom (moderate) and Agmatine (moderate).

By severity: 1 major · 208 moderate · 30 minor.

Open the Insulin Lispro interaction page ›

We hold 3 real supplement products containing Thiamine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Thiamine. Even though Thiamine itself has no known interaction with Insulin Lispro, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Natural Medicines records Insulin Lispro as a medicine that can lower these. This is not an interaction with Thiamine — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:

• COENZYME Q10›

Read the full Insulin Lispro nutrient depletion report ›

Thiamine is itself a nutrient we track — see which medications may deplete THIAMINE.

Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.