Drug & supplement interaction

Tylophora + Carvedilol

Carvedilol brand names: Coreg, Coreg CR.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Tylophora and Carvedilol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Carvedilol states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Tylophora and Carvedilol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Carvedilol and Tylophora in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Tylophora at all — not against Carvedilol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tylophora safety at a glance

Tylophora overall Use caution Evidence is limited and the plant can cause nausea, vomiting, and other side effects.
Pregnancy Avoid Not enough safety data, and traditional concerns suggest it should be avoided in pregnancy.
Breastfeeding Avoid Safety during breastfeeding is unknown, so it is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Carvedilol and Tylophora? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Tylophora and Carvedilol May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Vomiting / Nausea Additional detail

    Tylophora

    “Orally, Tylophora might cause nausea, vomiting, change in taste, and mouth soreness.”

    Tylophora · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    5 sources cited
    1. 29118. Mathew KK, Shivpuri DN. Treatment of asthma with alkaloids of Tylophora indica - a double blind study. Aspects of Allergy Appl Immunol 1974;7:166-179.
    2. 29119. Gupta S, George P, Gupta V, et al. Tylophora indica in bronchial asthma--a double blind study. Indian J Med Res 1979;69:981-989.
    3. 29120. Shivpuri DN, Menon MP, Prakash D. A crossover double-blind study on Tylophora indica in the treatment of asthma and allergic rhinitis. J Allergy 1969;43(3):145-150.
    4. 29121. Shivpuri DN, Menon MP, Parkash D. Preliminary studies in Tylophora indica in the treatment of asthma and allergic rhinitis. J Assoc Physicians India 1968;16(1):9-15.
    5. 29122. Shivpuri DN, Singhal SC, Parkash D. Treatment of asthma with an alcoholic extract of tylophora indica: a cross-over, double-blind study. Ann Allergy 1972;30(7):407-412.

    “Orally, Tylophora leaf has been reported to cause nausea in up to 10.8% of patients, vomiting in up to 16.6% of patients, mild upper abdominal pain in up to 5.6% of patients, and soreness of the mouth or loss of taste in up to 1.4% of patients in clinical research.”

    Tylophora · Natural Medicines adverse-effect record, reported in hypogeusia.

    5 sources cited
    1. 29118. Mathew KK, Shivpuri DN. Treatment of asthma with alkaloids of Tylophora indica - a double blind study. Aspects of Allergy Appl Immunol 1974;7:166-179.
    2. 29119. Gupta S, George P, Gupta V, et al. Tylophora indica in bronchial asthma--a double blind study. Indian J Med Res 1979;69:981-989.
    3. 29120. Shivpuri DN, Menon MP, Prakash D. A crossover double-blind study on Tylophora indica in the treatment of asthma and allergic rhinitis. J Allergy 1969;43(3):145-150.
    4. 29121. Shivpuri DN, Menon MP, Parkash D. Preliminary studies in Tylophora indica in the treatment of asthma and allergic rhinitis. J Assoc Physicians India 1968;16(1):9-15.
    5. 29122. Shivpuri DN, Singhal SC, Parkash D. Treatment of asthma with an alcoholic extract of tylophora indica: a cross-over, double-blind study. Ann Allergy 1972;30(7):407-412.

    Carvedilol

    Listed in the ADVERSE REACTIONS section of the FDA label for Carvedilol. Read the label on DailyMed ›

Reported for Tylophora but not commonly for Carvedilol: stomach pain, a change in taste and mouth irritation or sores.

Effects for Carvedilol come from the ADVERSE REACTIONS section of its FDA label; effects for Tylophora come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Carvedilol Products Have a Food Rule — Tylophora Should Not Break It

At least one FDA label for a product containing Carvedilol says to take it with food. If you take Tylophora on an empty stomach out of habit, keep them separate — and take Carvedilol with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Carvedilol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION COREG should be taken with food to slow the rate of absorption and reduce the incidence of orthostatic effects.

From the Dosage and Administration section of the FDA label we read for Carvedilol — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Tylophora or Carvedilol

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tylophora or Carvedilol, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Carvedilol

This page covers Tylophora only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Carvedilol page lists 211 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Grapefruit (major) and Indian Snakeroot (major).

By severity: 6 major · 171 moderate · 34 minor.

From our pharmacist’s overview on the Carvedilol page

“People take carvedilol (Coreg) for heart failure and high blood pressure, conditions where a sudden swing in pressure or heart rate matters, and its supplement list runs to 211 ingredients, so this one calls for genuine care. More than half of those entries lower blood pressure on their own, fish oil and celery seed among them, and can…”

Reviewed by 2 · Jul 18, 2026

Open the Carvedilol interaction page

How much people look this up

Where Tylophora and Carvedilol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tylophora
Top half

#701 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Carvedilol
Top 10%

#275 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tylophora reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Tylophora and Carvedilol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tylophora

What is Tylophora?

  • Asthma
  • Allergies and hay fever
  • Bronchitis and respiratory complaints
  • Inflammatory conditions
  • Digestive upset

Tylophora is a climbing plant used in traditional Indian (Ayurvedic) medicine, most often for asthma and breathing problems. Some older, small studies suggested possible benefit for asthma, but the evidence is weak and limited, and the plant can cause notable side effects. Talk to your pharmacist or doctor before trying it, and never use it to replace proven asthma treatments.

Tylophora indica · Apocynaceae · Leaves and roots · Capsules, dried leaf powder, tinctures, and traditional leaf preparations

An interaction check asks whether these two react with each other — it does not ask whether Tylophora is a good idea for someone in your situation. Here is what our Tylophora record says about it on its own.

Tylophora: dosing

There is no well-established or standardized dose for Tylophora. Older studies used small amounts of dried leaf for short periods, but these doses have not been confirmed as safe or effective.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Tylophora monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tylophora monograph & all interactions
Medication

About Carvedilol

What Is Carvedilol Used For?

Brand names: Coreg, Coreg CR

Carvedilol is used to treat three main conditions: mild-to-severe chronic heart failure, high blood pressure (hypertension), and reduced heart pumping function (left ventricular dysfunction) in people who have survived a heart attack. For heart failure, it is usually prescribed alongside other medications such as diuretics, ACE inhibitors, and digitalis to help people live longer and reduce the chance of hospital stays.

For people who have had a heart attack and whose heart is not pumping as well as it should, carvedilol is used to lower the risk of dying from heart-related causes. For high blood pressure, it can be used on its own or combined with other blood pressure medicines.

Most-Reported Side Effects for Carvedilol

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 9,141 reports
Dyspnea 8,542 reports
Diarrhea 7,250 reports
Dizziness 7,211 reports
Nausea 6,830 reports
See full Carvedilol drug information
Keep checking

Other Drugs & Tylophora

Browse every other medication we’ve checked against Tylophora — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Tylophora against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tylophora list.

See the full Tylophora interactions page
See every supplement checked against Carvedilol, ranked by severity
Evidence & sources

Tylophora References

The 6 references that drive our Tylophora monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Thiruvengadam KV, Haranath K, Sudarsan S, et al. Tylophora indica in bronchial asthma (a controlled comparison with a standard anti-asthmatic drug). J Indian Med Assoc 1978;71(7):172-176.
  2. Mathew KK, Shivpuri DN. Treatment of asthma with alkaloids of Tylophora indica - a double blind study. Aspects of Allergy Appl Immunol 1974;7:166-179.
  3. Gupta S, George P, Gupta V, et al. Tylophora indica in bronchial asthma--a double blind study. Indian J Med Res 1979;69:981-989.
  4. Shivpuri DN, Menon MP, Prakash D. A crossover double-blind study on Tylophora indica in the treatment of asthma and allergic rhinitis. J Allergy 1969;43(3):145-150.
  5. Shivpuri DN, Menon MP, Parkash D. Preliminary studies in Tylophora indica in the treatment of asthma and allergic rhinitis. J Assoc Physicians India 1968;16(1):9-15.
  6. Shivpuri DN, Singhal SC, Parkash D. Treatment of asthma with an alcoholic extract of tylophora indica: a cross-over, double-blind study. Ann Allergy 1972;30(7):407-412.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tylophora and Carvedilol Together: Common Questions

Is it safe to take Tylophora with Carvedilol?
We do not list a known interaction between Tylophora and Carvedilol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Tylophora and Carvedilol have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Tylophora and Carvedilol at the same time of day?
At least one FDA label for a product containing Carvedilol says to take it with food. If you take Tylophora on an empty stomach out of habit, keep them separate and take Carvedilol with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Carvedilol products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Carvedilol interact with any supplements?
Yes. Carvedilol has documented interactions with 211 supplements in our database — Tylophora is not one of them. The Carvedilol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tylophora monograph Uses, safety profile, and every drug interaction in one place Carvedilol drug information The full plain-English guide to this medication Carvedilol supplement interactions Every supplement checked against Carvedilol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Carvedilol and Tylophora?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.