Drug & supplement interaction

Tyrosine + Diflorasone

Diflorasone brand name: Psorcon.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Tyrosine and Diflorasone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Tyrosine and Diflorasone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Diflorasone and Tyrosine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tyrosine safety at a glance

Tyrosine overall Use caution Generally well tolerated in healthy adults, but talk to a healthcare provider before regular use.
Pregnancy Use caution Not enough safety data; avoid supplemental doses unless a doctor advises otherwise.
Breastfeeding Use caution Not enough safety data, so caution is advised while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Diflorasone and Tyrosine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Diflorasone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Diflorasone is filed under a single classification — topical drugs. Tyrosine has documented interactions with 2 drug classes — the most serious being levodopa (moderate) and thyroid hormone (moderate) — and none of Diflorasone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Tyrosine Does Interact With Other Medications

Tyrosine has 21 moderate known drug interactions in our database — Diflorasone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 21 No known interaction 2,809 (incl. Diflorasone)
Taking anything else?

Check Another of Your Medications Against Tyrosine

Covers the 2,830 medications we’ve checked against Tyrosine. Pick one to open its full report.

What to actually watch for

What Tyrosine Itself Has Been Linked To

This is not an interaction — nothing below involves Diflorasone. It is the side-effect record for Tyrosine on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Tyrosine, this list is the first place to look.

  • Heartburn / Nausea Additional detail

    “Orally, tyrosine can cause nausea and heartburn when taken at a dose of 150 mg/kg. Taking tyrosine 4 grams daily in combination with 5-hydroxytryptophan 800 mg and carbidopa 100 mg can cause diarrhea, nausea, and vomiting. These effects can be mitigated by lowering the dosage.”

    Tyrosine · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
    2. 918. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  • Drowsiness / Anxiety or restlessness Additional detail

    “Orally, larger doses of tyrosine (150 mg/kg) can cause headache and fatigue. Taking a combination of tyrosine 4 grams, 5-hydroxytryptophan 800 mg, and carbidopa 100 mg can cause drowsiness and agitation. These effects can be mitigated by lowering the dosage.”

    Tyrosine · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
    2. 918. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  • Joint pain Additional detail

    “Orally, larger doses of tyrosine (150 mg/kg) can cause arthralgia, but this is uncommon.”

    Tyrosine · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  • Tiredness / Headache Additional detail

    Recorded for Tyrosine in the same Natural Medicines adverse-effect record shown under Heartburn / Nausea above.

  • Diarrhea / Vomiting Additional detail

    Recorded for Tyrosine in the same Natural Medicines adverse-effect record shown under Heartburn / Nausea above.

Everything above comes from the Natural Medicines adverse-effect record for Tyrosine — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Diflorasone’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Diflorasone column appears here.

From our Q&A

Questions About Tyrosine or Diflorasone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tyrosine or Diflorasone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Diflorasone

This page covers Tyrosine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Diflorasone page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Diflorasone page

“DMSO is the ingredient to watch with diflorasone (Psorcon), a high-potency steroid cream for stubborn conditions like psoriasis. Applied to the same skin, DMSO may pull more of the steroid through than intended, amplifying both the benefit and side effects such as skin thinning.”

Reviewed by 2 · Jul 18, 2026

Open the Diflorasone interaction page

One more smart check

Taking Tyrosine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 4,448 real supplement products containing Tyrosine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tyrosine. Even though Tyrosine itself has no known interaction with Diflorasone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tyrosine and Diflorasone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tyrosine
Top 5%

#40 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Diflorasone
Steady interest

#1,493 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tyrosine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Tyrosine and Diflorasone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tyrosine

What is Tyrosine?

  • Mental focus and alertness
  • Coping with stress
  • Fatigue and sleep loss
  • Mood support
  • Athletic and cognitive performance

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss, or cold, but the evidence is mixed and it is not proven for everyday focus or mood. It is generally well tolerated in healthy adults, but check with your pharmacist or doctor before using it, especially during pregnancy or if you have a thyroid condition.

Amino acid (made in the body or produced by fermentation/synthesis for supplements) · Capsules, tablets, powder, and as L-tyrosine or N-acetyl-L-tyrosine

An interaction check asks whether these two react with each other — it does not ask whether Tyrosine is a good idea for someone in your situation. Here is what our Tyrosine record says about it on its own.

Tyrosine: dosing

There is no official standardized dose for tyrosine, and the amounts used in studies vary widely. Because of this, the best approach is to follow the directions on the product label and not exceed them.Doses are often based on body weight in research settings and taken a short time before a stressful or demanding task.

From our Tyrosine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tyrosine monograph & all interactions
Medication

About Diflorasone Topical

What Is Diflorasone Topical Used For?

Brand name: Psorcon

Diflorasone topical is used to treat inflammatory and itchy skin conditions that respond to corticosteroid treatment — broadly called corticosteroid-responsive dermatoses. Psorcon (diflorasone diacetate cream) is specifically indicated for the relief of inflammation and itching from these types of skin conditions.

See full Diflorasone Topical drug information
Keep checking

Other Drugs & Tyrosine

Browse every other medication we’ve checked against Tyrosine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
21Moderate
0Minor
2,808No known interaction
21 Moderate 2,808 No interaction
Moderate

21 interactions

No interaction 2,808 drugs checked — show the list

We also checked Tyrosine against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,808 medications checked with no known interaction — see the full Tyrosine list.

See the full Tyrosine interactions page
See every supplement checked against Diflorasone, ranked by severity
Evidence & sources

Tyrosine References

The 4 references that drive our Tyrosine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tyrosine and Diflorasone Together: Common Questions

Is it safe to take Tyrosine with Diflorasone?
We do not list a known interaction between Tyrosine and Diflorasone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Tyrosine and Diflorasone combination checked?
Interactions in our licensed database are recorded against drug classes. Diflorasone is filed under 1 classification, and Tyrosine has documented interactions with 2 drug classes — none of Diflorasone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Tyrosine interact with any other medications?
Yes. Tyrosine has 21 documented drug interactions in our database — Diflorasone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Diflorasone interact with any supplements?
Yes. Diflorasone has documented interactions with 3 supplements in our database — Tyrosine is not one of them. The Diflorasone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tyrosine monograph Uses, safety profile, and every drug interaction in one place Diflorasone Topical drug information The full plain-English guide to this medication Diflorasone supplement interactions Every supplement checked against Diflorasone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Diflorasone and Tyrosine?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.