Drug & supplement interaction

Water Germander + Denileukin

Denileukin brand name: Ontak.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Water Germander and Denileukin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Water Germander and Denileukin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Denileukin and Water Germander in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Water Germander at all — not against Denileukin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Water Germander safety at a glance

Water Germander overall Avoid Oral use has been linked to serious, sometimes fatal liver damage.
Pregnancy Avoid Not safe; avoid because of liver toxicity risk and lack of safety data.
Breastfeeding Avoid Not safe; avoid due to toxicity concerns and lack of data.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Denileukin and Water Germander? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Everything else you take

See Every Supplement That Interacts With Denileukin

This page covers Water Germander only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Denileukin page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Denileukin page

“Activated charcoal is the interaction I would settle first for anyone receiving denileukin (Ontak), a cancer treatment for cutaneous T-cell lymphoma. It carries the only major rating among the 17 supplements on file, and unlike the rest it can lower drug exposure no matter how the medicine is given, because it traps compounds that reci…”

Reviewed by 2 · Jul 18, 2026

Open the Denileukin interaction page

How much people look this up

Where Water Germander and Denileukin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Water Germander
Steady interest

#1,134 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Denileukin
Steady interest

#2,513 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Water Germander is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Water Germander reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Water Germander and Denileukin records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Water Germander

What is Water Germander?

  • Digestive upset
  • Weight loss aids
  • Fever
  • Oral hygiene and mouthwash
  • Gout

Water germander (often sold as the related plant wall germander, Teucrium chamaedrys) is a Mediterranean herb traditionally used for digestion and other ailments. Its oral use has been clearly linked to serious liver damage, including hepatitis and even death, so it is considered likely unsafe to take by mouth. We recommend avoiding it and talking to your pharmacist or doctor about safer options.

Teucrium chamaedrys · Lamiaceae · Aerial parts (leaves, flowering tops) · Tea, capsules, tinctures, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Water Germander is a good idea for someone in your situation. Here is what our Water Germander record says about it on its own.

Water Germander: dosing

Always read product labels carefully, since germander is sometimes hidden in herbal blends or weight-loss products.

From our Water Germander monograph — the full record covers uses, side effects and every documented interaction.

Read the full Water Germander monograph & all interactions
Medication

About Denileukin Diftitox Injection

What Is Denileukin Diftitox Injection Used For?

Brand name: Ontak

LYMPHIR is approved for adults with cutaneous T-cell lymphoma (CTCL) — a cancer that starts in certain white blood cells and mainly affects the skin — specifically Stage I through III disease that has relapsed (come back) or is refractory (no longer responding) after at least one prior systemic (whole-body) treatment.

It is not a first-line therapy. It's used when earlier treatments have already been tried and the cancer has continued to progress.

See full Denileukin Diftitox Injection drug information
Keep checking

Other Drugs & Water Germander

Browse every other medication we’ve checked against Water Germander — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Water Germander References

The 2 sources that drive our Water Germander monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Water Germander is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. LiverTox: Germander — NIH / NCBI Bookshelf Source
  2. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Water Germander and Denileukin Together: Common Questions

Is it safe to take Water Germander with Denileukin?
We do not list a known interaction between Water Germander and Denileukin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Denileukin interact with any supplements?
Yes. Denileukin has documented interactions with 17 supplements in our database — Water Germander is not one of them. The Denileukin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Denileukin and Water Germander?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.