Drug & supplement interaction

White Lily + Dofetilide

Dofetilide brand name: Tikosyn.

No Known Interaction
The bottom line No known interaction

We found no known interaction between White Lily and Dofetilide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

White Lily and Dofetilide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dofetilide and White Lily in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for White Lily at all — not against Dofetilide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

White Lily safety at a glance

White Lily overall Use caution Mostly used topically with limited safety data; skin reactions are possible.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dofetilide and White Lily? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Dofetilide’s Own FDA Label Lists

This is not an interaction — none of it involves White Lily. These are the most notable effects listed in the ADVERSE REACTIONS section of Dofetilide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • An irregular heartbeat Worth acting on mentioned in 14.5% of FDA reports for Dofetilide
  • A stroke or mini-stroke Worth acting on
  • A slow heartbeat Worth acting on
  • Heart failure Worth acting on
  • Fainting Worth acting on
  • Shortness of breath Worth acting on mentioned in 5.9% of FDA reports for Dofetilide
  • Chest pain Worth acting on
  • Raised blood pressure Worth acting on
  • A severe allergic reaction Worth acting on
  • Liver problems Worth acting on

Showing the 10 most notable of 28 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Dofetilide. Read the label on DailyMed › Where a percentage is shown, it is the share of 10,450 voluntary FDA FAERS reports for Dofetilide that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. White Lily’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no White Lily side to compare — that is a limit of the record, not a statement that White Lily has no side effects.

From our Q&A

Questions About White Lily or Dofetilide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers White Lily or Dofetilide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Dofetilide

This page covers White Lily only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dofetilide page lists 146 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 98 moderate · 40 minor.

From our pharmacist’s overview on the Dofetilide page

“Dofetilide (Tikosyn) controls abnormal heart rhythms, and it is dosed so precisely that most people start it in the hospital under ECG monitoring. Supplements deserve matching care.”

Reviewed by 2 · Jul 18, 2026

Open the Dofetilide interaction page

One more smart check

Taking White Lily as Part of a Dietary Supplement Product? Check It for Interactions

We hold 45 real supplement products containing White Lily, each one broken down to its full ingredient list — and combination products often carry several ingredients besides White Lily. Even though White Lily itself has no known interaction with Dofetilide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where White Lily and Dofetilide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement White Lily
Steady interest

#1,204 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dofetilide
Top half

#779 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. White Lily is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every White Lily reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The White Lily and Dofetilide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About White Lily

What is White Lily?

  • Skin soothing and minor wounds
  • Burns and skin irritation
  • Cosmetic and anti-aging skin care
  • Corns and calluses (traditional)
  • Inflamed or chapped skin

White Lily (Lilium candidum) is a flowering plant used mostly in traditional skin care, where its bulb- or flower-infused oils are applied for minor skin problems and soothing. Good-quality human studies are very limited, so most of its reputation comes from folk use rather than strong science. Talk with a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Lilium candidum · Liliaceae · Bulbs and flowers (sometimes prepared as oil or ointment) · Topical oils, ointments, infused oil, creams, and traditional poultices

An interaction check asks whether these two react with each other — it does not ask whether White Lily is a good idea for someone in your situation. Here is what our White Lily record says about it on its own.

White Lily: dosing

There is no established standardized dose for White Lily. It is sold mostly as topical oils, creams, and ointments, and amounts vary widely between products.If you use a commercial product, follow the directions on the label and apply only to the skin unless a professional tells you otherwise.

From our White Lily monograph — the full record covers uses, side effects and every documented interaction.

Read the full White Lily monograph & all interactions
Medication

About Dofetilide

What Is Dofetilide Used For?

Brand name: Tikosyn

Dofetilide capsules are used in two main ways for people with atrial fibrillation (AF) or atrial flutter (AFl) — abnormal, often rapid heart rhythms. First, they can help convert these abnormal rhythms back to a normal heart rhythm. Second, once a normal rhythm has been restored, dofetilide can help maintain it and delay the time before the abnormal rhythm comes back.

Because dofetilide can cause dangerous heart rhythm problems of its own, it is reserved for patients whose atrial fibrillation or atrial flutter causes significant symptoms. It has not been shown to be effective for paroxysmal atrial fibrillation (short, self-terminating episodes). The brand Tikosyn carries the same two approved uses.

Most-Reported Side Effects for Dofetilide

From FAERS, the FDA’s public side-effect reporting system (10,450 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Atrial fibrillation 1,066 reports
Dyspnea 612 reports
Dizziness 559 reports
Fatigue 531 reports
Electrocardiogram qt prolonged 446 reports
See full Dofetilide drug information
Keep checking

Other Drugs & White Lily

Browse every other medication we’ve checked against White Lily — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

White Lily References

The 2 sources that drive our White Lily monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. White Lily is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Poisonous Plants — MedlinePlus (U.S. National Library of Medicine) Source
  2. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking White Lily and Dofetilide Together: Common Questions

Is it safe to take White Lily with Dofetilide?
We do not list a known interaction between White Lily and Dofetilide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Dofetilide interact with any supplements?
Yes. Dofetilide has documented interactions with 146 supplements in our database — White Lily is not one of them. The Dofetilide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Dofetilide and White Lily?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.