Drug & supplement interaction

White Lily + Duloxetine

Duloxetine brand names: Cymbalta, Drizalma Sprinkle, Irenka.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between White Lily and Duloxetine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

White Lily and Duloxetine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Duloxetine and White Lily in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for White Lily at all — not against Duloxetine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

White Lily safety at a glance

White Lily overall Use caution Mostly used topically with limited safety data; skin reactions are possible.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Duloxetine and White Lily? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Duloxetine’s Own FDA Label Lists

This is not an interaction — none of it involves White Lily. These are the most notable effects listed in the ADVERSE REACTIONS section of Duloxetine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 9 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Serotonin syndrome Worth acting on
  • Thoughts of self-harm Worth acting on
  • Trouble passing urine Worth acting on
  • Low sodium Worth acting on
  • Fainting Worth acting on
  • Seizures Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on
  • Erection problems

Showing the 10 most notable of 29 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Duloxetine. Read the label on DailyMed › White Lily’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no White Lily side to compare — that is a limit of the record, not a statement that White Lily has no side effects.

Overlapping uses

What Duloxetine Is Prescribed For, and What White Lily Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Duloxetine is a prescription medicine with approved uses on its FDA label. White Lily is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Duloxetine is prescribed for: Duloxetine delayed-release capsules treat major depressive disorder (MDD) and generalized anxiety disorder (GAD) in adults. They also manage diabetic peripheral neuropathic pain (nerve pain from diabetes), fibromyalgia, and chronic musculoskeletal pain (such as chronic low back pain and pain from osteoarthritis) in adults. GAD is also approved in pediatric patients 7 years and older for Cymbalta, Drizalma Sprinkle, and certain duloxetine delayed-release capsule products. Fibromyalgia is approved in patients 13 years and older for Cymbalta and some duloxetine delayed-release capsule products.

Read the rest of what Duloxetine is prescribed for

Age-specific approvals vary by product — follow your prescriber's guidance on which product is right for your age group.

White Lily has been studied for:

  • Back pain studied, not established White Lily has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    White Lily for back pain

    It is unclear if topical white lily is beneficial in patients with back pain.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Duloxetine on your own; if you are taking White Lily for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About White Lily or Duloxetine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers White Lily or Duloxetine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Duloxetine

This page covers White Lily only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Duloxetine page lists 132 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Lithium (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 107 moderate · 20 minor.

Open the Duloxetine interaction page

One more smart check

Taking White Lily as Part of a Dietary Supplement Product? Check It for Interactions

We hold 45 real supplement products containing White Lily, each one broken down to its full ingredient list — and combination products often carry several ingredients besides White Lily. Even though White Lily itself has no known interaction with Duloxetine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where White Lily and Duloxetine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement White Lily
Steady interest

#749 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Duloxetine
Top 5%

#47 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. White Lily is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every White Lily reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The White Lily and Duloxetine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About White Lily

What is White Lily?

  • Skin soothing and minor wounds
  • Burns and skin irritation
  • Cosmetic and anti-aging skin care
  • Corns and calluses (traditional)
  • Inflamed or chapped skin

White Lily (Lilium candidum) is a flowering plant used mostly in traditional skin care, where its bulb- or flower-infused oils are applied for minor skin problems and soothing. Good-quality human studies are very limited, so most of its reputation comes from folk use rather than strong science. Talk with a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Lilium candidum · Liliaceae · Bulbs and flowers (sometimes prepared as oil or ointment) · Topical oils, ointments, infused oil, creams, and traditional poultices

An interaction check asks whether these two react with each other — it does not ask whether White Lily is a good idea for someone in your situation. Here is what our White Lily record says about it on its own.

White Lily: dosing

There is no established standardized dose for White Lily. It is sold mostly as topical oils, creams, and ointments, and amounts vary widely between products.If you use a commercial product, follow the directions on the label and apply only to the skin unless a professional tells you otherwise.

From our White Lily monograph — the full record covers uses, side effects and every documented interaction.

Read the full White Lily monograph & all interactions
Medication

About Duloxetine

What Is Duloxetine Used For?

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Duloxetine delayed-release capsules treat major depressive disorder (MDD) and generalized anxiety disorder (GAD) in adults. They also manage diabetic peripheral neuropathic pain (nerve pain from diabetes), fibromyalgia, and chronic musculoskeletal pain (such as chronic low back pain and pain from osteoarthritis) in adults.

GAD is also approved in pediatric patients 7 years and older for Cymbalta, Drizalma Sprinkle, and certain duloxetine delayed-release capsule products. Fibromyalgia is approved in patients 13 years and older for Cymbalta and some duloxetine delayed-release capsule products. Age-specific approvals vary by product — follow your prescriber's guidance on which product is right for your age group.

See full Duloxetine drug information
Keep checking

Other Drugs & White Lily

Browse every other medication we’ve checked against White Lily — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked White Lily against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full White Lily list.

See the full White Lily interactions page
See every supplement checked against Duloxetine, ranked by severity
Evidence & sources

White Lily References

The 2 sources that drive our White Lily monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. White Lily is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Poisonous Plants — MedlinePlus (U.S. National Library of Medicine) Source
  2. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking White Lily and Duloxetine Together: Common Questions

Is it safe to take White Lily with Duloxetine?
We do not list a known interaction between White Lily and Duloxetine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are White Lily and Duloxetine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for White Lily in each. That is a conversation for your prescriber, especially if Duloxetine is being adjusted to a target.
Does Duloxetine interact with any supplements?
Yes. Duloxetine has documented interactions with 132 supplements in our database — White Lily is not one of them. The Duloxetine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

White Lily monograph Uses, safety profile, and every drug interaction in one place Duloxetine drug information The full plain-English guide to this medication Duloxetine supplement interactions Every supplement checked against Duloxetine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Duloxetine and White Lily?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.