Drug & supplement interaction

Yucca + Omalizumab

Omalizumab brand name: Xolair.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Yucca and Omalizumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Yucca and Omalizumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Omalizumab and Yucca in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Yucca at all — not against Omalizumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Yucca safety at a glance

Yucca overall Use caution Generally considered low-risk in food amounts, but supplement safety is not well studied.
Pregnancy Avoid Not enough safety information is available, so it is best avoided.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Omalizumab and Yucca? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Yucca Itself Has Been Linked To

This is not an interaction — nothing below involves Omalizumab. It is the side-effect record for Yucca on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Yucca, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    “Topically, yucca has been reported to cause phytodermatitis. In one case report, an atopic gardener developed contact urticaria after occupational exposure to weeping fig, spathe flower, and yucca. Allergen skin tests were positive for all three plants.”

    Yucca · Natural Medicines adverse-effect record, reported in urticaria.

    2 sources cited
    1. 68294. Poljacki, M., Paravina, M., Jovanovic, M., Subotic, M., and Duran, V. [Contact allergic dermatitis caused by plants]. Med Pregl. 1993;46(9-10):371-375.
    2. 49961. <p><span>Kanerva, L., Estlander, T., Petman, L., Makinen-Kiljunen, S. Occupational allergic contact urticaria to yucca (Yucca aloifolia), weeping fig (Ficus benjamina), and spathe flower (Spathiphyllum wallisii). Allergy. 2001;56(10): 1008-11.</span></p>
  • A stuffy or runny nose Additional detail

    “Environmental exposure to yucca has been associated with allergic rhinitis in 59 patients who exhibited sensitization to yucca after allergen skin testing.”

    Yucca · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    1 source cited
    1. 86902. Mahillon, V., Saussez, S., and Michel, O. High incidence of sensitization to ornamental plants in allergic rhinitis. Allergy 2006;61(9):1138-1140. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Yucca — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Omalizumab’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Omalizumab column appears here.

Everything else you take

See Every Supplement That Interacts With Omalizumab

This page covers Yucca only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Omalizumab page lists 53 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Active Hexose Correlated Compound (ahcc) (moderate), Alfalfa (moderate), American Ginseng (moderate), Andrographis (moderate) and Ashwagandha (moderate).

By severity: 52 moderate · 1 minor.

From our pharmacist’s overview on the Omalizumab page

“None of the 53 supplements on file for omalizumab (Xolair) carries a major rating, so this is a list to read with steady attention rather than alarm. Xolair treats allergic asthma and chronic hives by calming part of the immune system, and every entry here pulls the other way: these are immune-stimulating products, echinacea and astrag…”

Reviewed by 2 · Jul 18, 2026

Open the Omalizumab interaction page

One more smart check

Taking Yucca as Part of a Dietary Supplement Product? Check It for Interactions

We hold 370 real supplement products containing Yucca, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yucca. Even though Yucca itself has no known interaction with Omalizumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Yucca and Omalizumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Yucca
Top half

#388 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Omalizumab
Steady interest

#2,117 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yucca reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Yucca and Omalizumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Yucca

What is Yucca?

  • Joint pain and arthritis
  • Digestive health
  • High cholesterol
  • Inflammation
  • High blood pressure

Yucca is a desert plant traditionally used for joint pain, arthritis, and digestion, and it contains compounds called saponins thought to have anti-inflammatory effects. Human evidence for these uses is very limited, so it should not replace proven treatments. Talk to your pharmacist or doctor before trying it, especially if you are pregnant, breastfeeding, or take other medicines.

Yucca schidigera · Asparagaceae · Root, stem (trunk), and leaves · Capsules, tablets, powder, liquid extract, and tea

An interaction check asks whether these two react with each other — it does not ask whether Yucca is a good idea for someone in your situation. Here is what our Yucca record says about it on its own.

Yucca: dosing

There is no well-established standard dose for yucca supplements. Doses vary widely between products, and there is not enough research to recommend a specific amount.If you choose to try yucca, follow the directions on the product label and do not exceed them. A pharmacist or doctor can help you decide whether it is appropriate for you and review it against your other medications and health conditions.

From our Yucca monograph — the full record covers uses, side effects and every documented interaction.

Read the full Yucca monograph & all interactions
Medication

About Omalizumab Injection

What Is Omalizumab Injection Used For?

Brand name: Xolair

Xolair is used for several allergy-driven conditions. It treats moderate to severe persistent asthma in adults and children 6 and older whose symptoms aren't controlled by inhaled steroids alone and who test positive for a year-round airborne allergen. It is also used as an add-on maintenance treatment for chronic rhinosinusitis with nasal polyps (ongoing sinus inflammation with polyp growths) in adults 18 and older who haven't responded well to nasal corticosteroids.

Xolair is also approved to reduce allergic reactions — including anaphylaxis — from accidental food exposure in adults and children aged 1 and older with IgE-mediated food allergy. It must be used alongside strict food avoidance, and it is not a substitute for emergency treatment like epinephrine. Finally, Xolair treats chronic spontaneous urticaria (persistent hives with no identified trigger) in adults and adolescents 12 and older who still have symptoms despite antihistamine treatment.

See full Omalizumab Injection drug information
Keep checking

Other Drugs & Yucca

Browse every other medication we’ve checked against Yucca — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Yucca References

The 3 references that drive our Yucca monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. <p><span>Kanerva, L., Estlander, T., Petman, L., Makinen-Kiljunen, S. Occupational allergic contact urticaria to yucca (Yucca aloifolia), weeping fig (Ficus benjamina), and spathe flower (Spathiphyllum wallisii). Allergy. 2001;56(10): 1008-11.</span></p>
  2. Poljacki, M., Paravina, M., Jovanovic, M., Subotic, M., and Duran, V. [Contact allergic dermatitis caused by plants]. Med Pregl. 1993;46(9-10):371-375.
  3. Mahillon, V., Saussez, S., and Michel, O. High incidence of sensitization to ornamental plants in allergic rhinitis. Allergy 2006;61(9):1138-1140. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Yucca and Omalizumab Together: Common Questions

Is it safe to take Yucca with Omalizumab?
We do not list a known interaction between Yucca and Omalizumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Omalizumab interact with any supplements?
Yes. Omalizumab has documented interactions with 53 supplements in our database — Yucca is not one of them. The Omalizumab interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Omalizumab and Yucca?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.