Indium Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Indium interacts with medications. The heart of this page is the interaction list — every drug Indium is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Indium is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Indium against your medication
Add one medicationDrugs that interact with Indium
0 medications have a known interaction with Indium, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Indium. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Indium combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Indium: Uses, Safety & Side Effects
Indium is a metallic chemical element sometimes sold as a liquid 'trace mineral' supplement with bold anti-aging and energy claims, but it is not a recognized essential nutrient and there is no reliable human evidence that it offers any health benefit. Because safety data are very limited and it is a heavy metal, most people should avoid it and talk with a pharmacist or doctor first.
- Part used
- Not a plant; a chemical element (indium) sold as a mineral supplement
- Common forms
- Liquid 'indium sulfate' drops, sometimes capsules
- Anti-aging
- Boosting energy
- Supporting hormone or gland function
- General 'wellness' or trace mineral supplementation
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Indium is not an essential nutrient and lacks reliable human safety or benefit data.
When used orally. The effect of indium on the fetus or breast-feeding newborn is not known; however, indium compounds are thought to be toxic to many...
Read the full pregnancy detailWhen used orally. The effect of indium on the fetus or breast-feeding newborn is not known; however, indium compounds are thought to be toxic to many...
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Indium is a soft, silvery metallic chemical element (symbol In). It is not an herb or a plant; it is a metal mostly used in industry, such as in electronics, screens, and solders. It is found in tiny amounts in the earth, often alongside zinc ores.
In the supplement world, indium is usually sold as a liquid mineral product, often labeled as 'indium sulfate.' Marketers promote it as a 'master mineral' or trace element. These products are sold online and in some health stores, often with strong promises about energy, aging, and hormone balance.
It is important to know that indium is not considered an essential nutrient. Your body does not require indium to function, and the marketing claims around it are not backed by solid science.
How it works
Sellers sometimes claim that indium acts on the hypothalamus and pituitary glands to 'balance' hormones, or that it helps the body absorb other minerals. These ideas are not supported by good scientific evidence.
There is no established biological role for indium in the human body, and no proven mechanism by which a supplement form would produce the benefits that are advertised. Any explanations you see are largely theoretical or promotional, not based on solid laboratory or clinical data.
Does Indium work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
Effective Cancer diagnosis
Indium (In-111) pentetreotide injection (OctreoScan) is an FDA-approved prescription product for use in diagnosing primary and metastatic neuroendocrine tumors bearing somatostatin receptors.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
Indium is a heavy metal, and its long-term safety as a supplement has not been well studied in people. Workplace studies in industries that handle indium compounds have raised concerns about lung problems with inhalation, which is a different exposure than swallowing a supplement, but it shows the body does not handle this metal as a harmless nutrient.
Because there is no clear safe dose and no proven benefit, most people are best off avoiding indium supplements. Children, people with kidney or liver disease, and anyone with a chronic health condition should not use it without medical guidance.
For pregnancy and breastfeeding, there is no safety information, so it should be avoided. When in doubt, talk with your pharmacist or doctor before taking any product containing indium.
Side effects
Because indium supplements have not been carefully studied, the full range of possible side effects is unknown. Some users report a metallic taste or stomach upset.
As a heavy metal, there is a theoretical concern about buildup in the body and possible harm to organs such as the kidneys or liver with regular use. If you take indium and notice any new symptoms—such as nausea, fatigue, or changes in urination—stop using it and seek medical advice.
Indium: Reported Adverse Effects
Documented safety reports on Indium from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Reports by conditionChronic obstructive pulmonary disease (COPD) Pulmonary/Respiratory
Occupational exposure to indium by inhalation can lead to potentially fatal interstitial lung disease, characterized by pulmonary alveolar proteinosis, progressing to fibrosis with or without emphysema. The disease develops slowly with shortness of breath, chest tightness and pain, dry cough, dyspnea, and deteriorating pulmonary function tests. Abnormalities seen with high-resolution computed tomography include subpleural honeycomb, diffuse centrilobular emphysema, and diffuse reticulonodular infiltration. Serum indium levels are elevated, and severity is linked to the level and duration of exposure. Once exposure stops, accumulated indium clears extremely slowly from the lungs and the disease may not be reversible.
Skin irritation Dermatologic
Topically, indium can cause skin irritation.
- Indium. Material Safety Data Sheet. Science Lab, October 2005.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no established or recommended dose for indium, because it is not an essential nutrient and has no proven benefit. Products that contain it are not standardized, and label amounts vary.
We do not recommend a specific dose. If you are considering a product that contains indium, read the label carefully and check with a pharmacist or doctor first. In general, the safest choice is to avoid it.
Indium & Pregnancy
Indium & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 5 references that drive our Indium monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Miyaki K, Hosoda K, Hirata M, et al. Biological monitoring of indium by means of graphite furnace atomic absorption spectrophotometry in workers exposed to particles of indium compounds. J Occup Health 2003;45:228-30. PubMed
- Indium. Material Safety Data Sheet. Science Lab, October 2005.
- Indium In-111 pentetreotide injection (OctreoScan) Package Insert. Curium US LLC, Maryland Heights, MO. 2018. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=93d8f3b2-1216-41dc-a63d-0e812b33891d. Accessed April 25, 2020.
- Tsao YC, Fan HY, Luo JJ. Case reports of indium lung disease in Taiwan. J Formos Med Assoc. 2021 Feb;120(2):893-8. PubMed
- Yang J, Zhang W, Feng J. Low serum indium levels induce expression disorders of some inflammatory factors. Int Arch Occup Environ Health. 2021 Jan;94(1):23-30. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Indium
28 brands in our database make a supplement containing Indium.
Supplement products with Indium
55 products in our database contain Indium. Open any to see its full ingredient list and every drug interaction we check.
Indium: Common Questions
What is Indium used for, and does it work?
Does Indium interact with prescription medications?
How are Indium interactions rated?
Is it safe to take Indium with my medications?
Where does this Indium interaction information come from?
What is Indium used for?
Is Indium an essential nutrient?
Is Indium safe to take?
Can I take Indium while pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Indium
A rotating sample of real supplements in our database that list Indium — open any to see its full ingredients and every drug interaction we check.
- Indium Concentrate by Complete H2O Minerals
- Vegan Nightime Multi-Vitamin by Tropical Oasis
- Trace-Mins by NaturesPlus
- Fulvic Trace Minerals by Good State
- ORME Oxygen+ by Ambaya Gold
- Uplift by Organa
- Complete Essentials Concentrate by Complete H2O Minerals
- Advanced Multiple by BodSmith
- Complete Multiple Natural Berry Flavor by Liquid Health
- Multiplex Complete Wild Berry Flavor by NuMedica
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