Parsnip Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Parsnip interacts with medications. The heart of this page is the interaction list — every drug Parsnip is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Parsnip is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Parsnip against your medication
Add one medicationDrugs that interact with Parsnip
0 medications have a known interaction with Parsnip, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Parsnip. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Parsnip combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Parsnip: Uses, Safety & Side Effects
Parsnip is mainly a nutritious root vegetable that is safe and healthy as part of a normal diet. Its use as a concentrated supplement or herbal remedy is not well studied, and certain parts of the plant can make skin very sensitive to sunlight. Talk to your pharmacist or doctor before using parsnip in any medicinal or high-dose form.
- Scientific name
- Pastinaca sativa
- Family
- Apiaceae
- Part used
- Root, leaves, seeds, and essential oil
- Common forms
- Whole root (food), cooked vegetable, juice, dried seeds, and rarely supplements or essential oil
- Digestive support
- Mild diuretic ('water pill') effect
- Nutritional/dietary fiber source
- Traditional kidney and urinary support
- General wellness
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Safe as a food, but its leaves, sap, and seeds contain compounds that can cause skin reactions with sun exposure.
Insufficient reliable information available; avoid using in amounts larger than those found in foods.
Read the full pregnancy detailInsufficient reliable information available; avoid using in amounts larger than those found in foods.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Parsnip (Pastinaca sativa) is a root vegetable closely related to carrots, celery, and parsley. It has a cream-colored root with a sweet, nutty flavor and is commonly eaten roasted, boiled, or mashed.
Parsnip is native to Europe and Asia and now grows in many temperate parts of the world, including North America. It is most often used as a food, but the root, leaves, and seeds have also been used in traditional folk remedies.
As a vegetable, parsnip provides fiber, vitamin C, folate, potassium, and other nutrients. Its use as a concentrated herbal supplement is uncommon and not well researched.
Uses & effectiveness
People have traditionally used parsnip for digestion, as a mild diuretic (to help the body release water), and to support the kidneys and urinary tract. These uses come mostly from folk tradition rather than strong scientific testing.
The evidence for parsnip as a medicine is very limited. There are few high-quality human studies on parsnip for any specific health condition. Most of what we know comes from its nutritional content as a food or from early laboratory research on its plant compounds.
Bottom line: parsnip is a healthy vegetable and a good source of fiber and nutrients, but there is not enough reliable evidence to recommend it as a treatment for any particular illness.
How it works
As a food, parsnip provides dietary fiber, which supports regular digestion, along with vitamins and minerals that contribute to overall health.
Parsnip also contains natural plant compounds called furanocoumarins (such as psoralens). In laboratory studies, these compounds have shown various biological effects. However, furanocoumarins are also responsible for making skin more sensitive to sunlight, which can lead to burns or rashes.
It is important to know that most proposed medicinal effects are based on laboratory or animal research, not on well-designed human studies. We cannot assume these effects apply to people who eat or take parsnip.
Safety & precautions
Parsnip is widely eaten and is considered safe as a normal food for most people. Cooking does not remove its nutritional value.
The main safety concern is phototoxicity. The leaves, stems, sap, and seeds of the parsnip plant contain furanocoumarins that can cause a skin reaction called phytophotodermatitis. This happens when the plant juice gets on the skin and the skin is then exposed to sunlight, leading to redness, blistering, and burns. People who handle, harvest, or forage wild parsnip should wear gloves and protective clothing.
People with allergies to other plants in the carrot/celery family (Apiaceae) may also react to parsnip.
Pregnancy and breastfeeding: Eating parsnip as a vegetable is generally fine. However, concentrated supplements, extracts, seeds, or essential oil have not been studied for safety during pregnancy or breastfeeding, so these should be avoided unless your doctor advises otherwise.
Side effects
When eaten as a normal food, parsnip rarely causes problems beyond occasional gas or bloating from its fiber content.
The most notable side effect involves the skin: contact with the plant's sap or leaves followed by sun exposure can cause burns, blisters, and rashes. Allergic reactions are possible in people sensitive to related plants like carrot, celery, or parsley.
Eating very large or unusual amounts of parsnip, or using concentrated extracts, may increase exposure to furanocoumarins, but the effects of this are not well studied.
Parsnip: Reported Adverse Effects
Documented safety reports on Parsnip from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Topically, contact dermatitis and phototoxic reactions (including skin blisters) are possible following exposure to parsnip sap or fresh parsnip root and exposure to sunlight. Allergic contact dermatitis can occur but is rare.
- Ivie GW, Holt DL, Ivey MC. Natural toxicants in human foods: psoralens in raw and cooked parsnip root. Science 1981;213:909-10..
- Lutchman, L., Inyang, V., and Hodgkinson, D. Phytophotodermatitis associated with parsnip picking. J.Accid.Emerg.Med. 1999;16(6):453-454.
- Aberer, W. Occupational dermatitis from organically grown parsnip (Pastinaca sativa L.). Contact Dermatitis 1992;26(1):62.
- Bang, Pedersen N. and Pla Arles, U. B. Phototoxic reaction to parsnip and UV-A sunbed. Contact Dermatitis 1998;39(2):97.
Dermatitis Dermatologic
Topically, contact dermatitis and phototoxic reactions, including skin blisters and later hyperpigmentation, have occurred following exposure to parsnip sap or fresh parsnip root and exposure to sunlight or UV-A light from a sunbed. Light-skinned people may be particularly susceptible to these reactions.
A case report describes a 51-year-old male who developed rashes on his hands after preparing parsnip. These resolved within 3 days with moisturizing cream, and did not recur when he avoided contact with parsnip. Another case report describes a 10-month-old male who developed non-pruritic perioral erythema, lip edema, and a painful bullous eruption on the chin and cheeks after contact with a homemade parsnip baby food eaten outside in the sun. He required topical and systemic treatment. The plaques and blisters resolved after 10 days, but residual pigmentation remained and only faded gradually over 10 months with sun avoidance.
- Ivie GW, Holt DL, Ivey MC. Natural toxicants in human foods: psoralens in raw and cooked parsnip root. Science 1981;213:909-10..
- Lutchman, L., Inyang, V., and Hodgkinson, D. Phytophotodermatitis associated with parsnip picking. J.Accid.Emerg.Med. 1999;16(6):453-454.
- Aberer, W. Occupational dermatitis from organically grown parsnip (Pastinaca sativa L.). Contact Dermatitis 1992;26(1):62.
- Bang, Pedersen N. and Pla Arles, U. B. Phototoxic reaction to parsnip and UV-A sunbed. Contact Dermatitis 1998;39(2):97.
- White JML, Pink AE. English Sunday lunch dermatitis: Allergic contact dermatitis to parsnip, carrot, fennel (and ivy). Contact Dermatitis. 2020 Oct;83(4):317-8.
- Lafon A, Boulard C. Perioral phytophotodermatitis induced by parsnip mash. Contact Dermatitis. 2020 Oct;83(4):318-9.
Dermatitis Immunologic
Topically, contact dermatitis is rare following exposure to fresh parsnip root.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no established medicinal dose for parsnip. As a food, it is simply eaten as a vegetable in normal serving amounts.
If you choose to use a parsnip supplement, juice, or extract, there is no standardized dose backed by research. Follow the directions on the product label and check with your pharmacist or doctor first, especially if you are pregnant, breastfeeding, or have a medical condition.
Parsnip & Pregnancy
Parsnip & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 6 references that drive our Parsnip monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Ivie GW, Holt DL, Ivey MC. Natural toxicants in human foods: psoralens in raw and cooked parsnip root. Science 1981;213:909-10.. PubMed
- Lutchman, L., Inyang, V., and Hodgkinson, D. Phytophotodermatitis associated with parsnip picking. J.Accid.Emerg.Med. 1999;16(6):453-454. PubMed
- Aberer, W. Occupational dermatitis from organically grown parsnip (Pastinaca sativa L.). Contact Dermatitis 1992;26(1):62.
- Bang, Pedersen N. and Pla Arles, U. B. Phototoxic reaction to parsnip and UV-A sunbed. Contact Dermatitis 1998;39(2):97. PubMed
- White JML, Pink AE. English Sunday lunch dermatitis: Allergic contact dermatitis to parsnip, carrot, fennel (and ivy). Contact Dermatitis. 2020 Oct;83(4):317-8. PubMed
- Lafon A, Boulard C. Perioral phytophotodermatitis induced by parsnip mash. Contact Dermatitis. 2020 Oct;83(4):318-9. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Parsnip
11 brands in our database make a supplement containing Parsnip.
Supplement products with Parsnip
48 products in our database contain Parsnip. Open any to see its full ingredient list and every drug interaction we check.
Parsnip: Common Questions
Does Parsnip interact with prescription medications?
How are Parsnip interactions rated?
Is it safe to take Parsnip with my medications?
Where does this Parsnip interaction information come from?
Is Parsnip safe to eat?
Why can Parsnip cause skin reactions?
Can I take Parsnip while pregnant or breastfeeding?
Does Parsnip have proven health benefits as a supplement?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Parsnip
A rotating sample of real supplements in our database that list Parsnip — open any to see its full ingredients and every drug interaction we check.
- Source of Life Gold Drink Mix Delicious Tropical Fruit Flavor by NaturesPlus
- intraMAX 2.0 Peach Mango Flavor by Drucker Labs
- Immu-Support Formula by Douglas Laboratories
- Source of Life Gold Liquid Delicious Tropical Fruit Flavor by NaturesPlus
- Prenatal by Natures Plus Source of Life
- Gold Liquid Delicious Tropical Fruit Flavor by NaturesPlus Source of Life
- Source of Life Gold Mini-Tabs by NaturesPlus
- Parsnip 450 mg by TerraVita Premium Collection
- Lung Cleanser by Esmond Natural
- Hair, Skin & Nails by Natures Plus Herbal Actives
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