Medication interaction hub

What Supplements Interact with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Aclidinium Bromide, Formoterol Fumarate Dihydrate brand name: Duaklir Pressair. Every interaction below applies to the brands too.

42 Interactions 8 Major 32 Moderate 2 Minor
Curated & coded by · Clinical Pharmacist · Updated October 2, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Aclidinium Bromide, Formoterol Fumarate Dihydrate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Aclidinium Bromide, Formoterol Fumarate Dihydrate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Grapefruit is the entry I would flag first for anyone using Duaklir Pressair (aclidinium and formoterol), a twice-daily inhaler for COPD. In large amounts, grapefruit juice can add to the heart rhythm effect (QT prolongation) that this class of bronchodilator already carries, and it is one of eight major-rated interactions among the 42 ingredients on file here. Those eight deserve genuine vigilance, not a passing glance.

The full list tells two stories. Thirteen ingredients, including ephedra, cesium, and arsenic, share that same rhythm risk. The other thirty act on the same nerve pathway as aclidinium. Most of those, rated moderate with only two minors, pile on effects like dry mouth, blurred vision, and trouble urinating, while a few, such as bacopa and clubmoss, may instead blunt the inhaler itself. Since a weakened inhaler can mean a COPD flare, that quieter group matters too.

— , Clinical Pharmacist · July 18, 2026

Major 8 Moderate 32 Minor 2 No known interaction 1,410

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Aclidinium Bromide, Formoterol Fumarate Dihydrate: Top Interactions at a Glance

The most significant Aclidinium Bromide, Formoterol Fumarate Dihydrate supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 42 interacting ingredients — plus 1,410 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Aclidinium Bromide, Formoterol Fumarate Dihydrate + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Arsenic + Aclidinium Bromide, Formoterol Fumarate Dihydratei

Arsenic trioxide can prolong the QT interval.

Read the full interaction Major Likelihood Probable Cesium + Aclidinium Bromide, Formoterol Fumarate Dihydratei

Theoretically, taking cesium concomitantly with other drugs that prolong the QT interval may increase the risk of ventricular arrhythmias and death.

Read the full interaction Major Likelihood Probable Ephedra + Aclidinium Bromide, Formoterol Fumarate Dihydratei

Theoretically, ephedra might have an additive effect with drugs that prolong the QT interval.

Read the full interaction Major Likelihood Probable Grapefruit + Aclidinium Bromide, Formoterol Fumarate Dihydratei

Grapefruit or grapefruit juice, especially if consumed in large amounts, can cause additive QT interval prolongation when taken with QT interval-prolonging drug...

Read the full interaction Major Likelihood Probable Henbane + Aclidinium Bromide, Formoterol Fumarate Dihydratei

Concomitant use of henbane can have additive anticholinergic effects and adverse effects with amantadine, antihistamines, atropine, belladonna alkaloids, hyoscy...

Read the full interaction Major Likelihood Probable Scopolia + Aclidinium Bromide, Formoterol Fumarate Dihydratei

The alkaloid constituents of scopolia, including hyoscyamine, scopolamine, and atropine, could potentiate the effects and adverse effects of anticholinergic dru...

Read the full interaction
The complete list

Every Supplement Checked Against Aclidinium Bromide, Formoterol Fumarate Dihydrate

All 1,452 ingredients in our database, ranked by severity — 42 with a Aclidinium Bromide, Formoterol Fumarate Dihydrate interaction on file and 1,410 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Aclidinium Bromide, Formoterol Fumarate Dihydrate?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take European Mandrake with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concurrent use may cause additive anticholinergic effects and adverse effects.

Full European Mandrake + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Evodia with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, evodia might have an additive effect with drugs that prolong the QT interval, potentially increasing the risk of ventricular...

Full Evodia + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Huperzine A with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, huperzine A might decrease the effects of anticholinergic drugs.

Full Huperzine A + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Iboga with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, iboga may have an additive effect with drugs that prolong the QT interval.

Full Iboga + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Jimson Weed with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, jimson weed may increase anticholinergic effects and adverse effects.

Full Jimson Weed + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take K2/spice with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, K2/spice might have an additive effect with drugs that prolong the QT interval and increase the risk of ventricular arrhythmi...

Full K2/spice + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Marjoram with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity.

Full Marjoram + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Methylene Blue with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Methylene Blue + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Nutmeg with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of nutmeg and anticholinergic drugs might decrease the effectiveness of either agent.

Full Nutmeg + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Panax Ginseng with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Panax ginseng has an additive effect with drugs that prolong the QT interval and potentially increase the risk of ventricular...

Full Panax Ginseng + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Phosphatidylserine with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Full Phosphatidylserine + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Poria Mushroom with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.

Full Poria Mushroom + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Puravive with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Puravive contains Panax ginseng.

Full Puravive + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Purple Nut Sedge with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, purple nut sedge dose-dependently inhibits acetylcholinesterase (AChE).

Full Purple Nut Sedge + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Sage with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sage might decrease the clinical effects of anticholinergic drugs.

Full Sage + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Syrian Rue with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Syrian rue might decrease the effects of anticholinergic drugs.

Full Syrian Rue + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Teazle with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that teazle extract can inhibit acetylcholinesterase activity.

Full Teazle + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Thyme with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of anticholinergic drugs and thyme essential oil might reduce the effects of anticholinergic drugs.

Full Thyme + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Toothed Clubmoss with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopol...

Full Toothed Clubmoss + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer

Can you take Wild Lettuce with Aclidinium Bromide, Formoterol Fumarate Dihydrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.

Full Wild Lettuce + Aclidinium Bromide, Formoterol Fumarate Dihydrate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Aclidinium Bromide, Formoterol Fumarate Dihydrate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aclidinium Bromide, Formoterol Fumarate Dihydrate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Aclidinium Bromide, Formoterol Fumarate Dihydrate sits in 2 interaction categories. Open any one to see what the group means:

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Aclidinium Bromide, Formoterol Fumarate Dihydrate through this category.

Qt Interval-Prolonging Drugs 13 ingredients

Medications that can affect the heart's electrical rhythm (the QT interval). Supplements with similar effects can add to that risk.

13 of the supplement ingredients on this page reach Aclidinium Bromide, Formoterol Fumarate Dihydrate through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Aclidinium Bromide, Formoterol Fumarate Dihydrate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aclidinium Bromide, Formoterol Fumarate Dihydrate.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

Aclidinium Bromide, Formoterol Fumarate Dihydrate & Supplements: Common Questions

What supplements interact with Aclidinium Bromide, Formoterol Fumarate Dihydrate?
More than you might expect — 42 in total, though they are far from equal: 8 are rated major, 32 moderate, and 2 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Arsenic, Cesium, Ephedra.
Which Aclidinium Bromide, Formoterol Fumarate Dihydrate supplement interactions are the most serious?
Focus on the major group: Arsenic, Cesium, Ephedra, Grapefruit and Henbane, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Aclidinium Bromide, Formoterol Fumarate Dihydrate?
Usually yes — most people on Aclidinium Bromide, Formoterol Fumarate Dihydrate can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Duaklir Pressair have the same supplement interactions as Aclidinium Bromide, Formoterol Fumarate Dihydrate?
Yes — Duaklir Pressair all contain Aclidinium Bromide, Formoterol Fumarate Dihydrate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Aclidinium Bromide, Formoterol Fumarate Dihydrate and my other medications?
This page covers Aclidinium Bromide, Formoterol Fumarate Dihydrate against supplements and herbal ingredients. Checking Aclidinium Bromide, Formoterol Fumarate Dihydrate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of October 2, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.