Medication interaction hub

What Supplements Interact with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Aspirin, Caffeine, Phenacetin, Propoxyphene brand name: Margesic Comp. 65. Every interaction below applies to the brands too.

414 Interactions 17 Major 350 Moderate 47 Minor
Curated & coded by · Clinical Pharmacist · Updated September 18, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Aspirin, Caffeine, Phenacetin, Propoxyphene? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Aspirin, Caffeine, Phenacetin, Propoxyphene against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Margesic Comp. 65 packs four drugs into one tablet, aspirin, caffeine, phenacetin, and the sedating opioid propoxyphene, which is why 414 supplement ingredients appear on this page and why I would slow down before adding any of them. More than 200 can add to aspirin's blood-thinning effect and raise bleeding risk, while another 78, kava, beer, and wine among them, deepen the opioid's sedation, and that sedation group holds several of the 17 major-rated entries.

The rest of the list pulls in gentler but real ways. Some 44 stimulant herbs stack onto the caffeine, 38 can stress the liver alongside phenacetin, and over a hundred change how the body clears the opioid through liver enzymes, grapefruit being the standout since it can push levels up. With 350 moderate and 47 minor entries below the majors, start your reading at the top, and treat alcohol as the clearest thing to skip.

— , Clinical Pharmacist · July 18, 2026

Major 17 Moderate 350 Minor 47 No known interaction 1,038

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Aspirin, Caffeine, Phenacetin, Propoxyphene: Top Interactions at a Glance

The Aspirin, Caffeine, Phenacetin, Propoxyphene supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 414 interacting ingredients — plus 1,038 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Aspirin, Caffeine, Phenacetin, Propoxyphene Combinations Today

The Aspirin, Caffeine, Phenacetin, Propoxyphene + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Niacin + Aspirin, Caffeine, Phenacetin, Propoxyphenei

Theoretically, concomitant use of niacin and hepatotoxic drugs might increase the risk of hepatotoxicity.

Read the full interaction Moderate Likelihood Possible Hawthorn + Aspirin, Caffeine, Phenacetin, Propoxyphenei

Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Minor Likelihood Unlikely Mullein + Aspirin, Caffeine, Phenacetin, Propoxyphenei

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the...

Read the full interaction Minor Likelihood Possible Hemp + Aspirin, Caffeine, Phenacetin, Propoxyphenei

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.

Read the full interaction Moderate Likelihood Possible Bitter Orange + Aspirin, Caffeine, Phenacetin, Propoxyphenei

Bitter orange might increase levels of drugs metabolized by CYP3A4.

Read the full interaction Moderate Likelihood Possible Parsley + Aspirin, Caffeine, Phenacetin, Propoxyphenei

Theoretically, parsley might increase serum levels of CYP1A2 substrates.

Read the full interaction
The complete list

Every Supplement Checked Against Aspirin, Caffeine, Phenacetin, Propoxyphene

All 1,452 ingredients in our database, ranked by severity — 414 with a Aspirin, Caffeine, Phenacetin, Propoxyphene interaction on file and 1,038 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Aspirin, Caffeine, Phenacetin, Propoxyphene?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Niacin with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of niacin and hepatotoxic drugs might increase the risk of hepatotoxicity.

Full Niacin + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Hawthorn with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Hawthorn + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Mullein with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, a...

Full Mullein + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Hemp with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.

Full Hemp + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Bitter Orange with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bitter orange might increase levels of drugs metabolized by CYP3A4.

Full Bitter Orange + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Isopropylnorsynephrine with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking isopropylnorsynephrine with stimulant drugs might have additive effects and increase the risk of adverse cardiovascula...

Full Isopropylnorsynephrine + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Jackfruit with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, jackfruit seeds might cause additive sedation when taken with CNS depressants.

Full Jackfruit + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Jamaican Dogwood with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Jamaican dogwood may potentiate sedative effects.

Full Jamaican Dogwood + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Japanese Apricot with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Some constituents of Japanese apricot flower extract might have antiplatelet properties.

Full Japanese Apricot + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Japanese Persimmon with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is concern that Japanese persimmon leaf constituents might potentiate effects of anticoagulant and antiplatelet drugs.

Full Japanese Persimmon + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Jequirity with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that constituents of jequirity beans can inhibit platelet aggregation.

Full Jequirity + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Jiaogulan with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, jiaogulan might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Jiaogulan + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Khat with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Cathinone, a constituent of khat, appears to have sympathomimetic effects and can increase blood pressure and heart rate.

Full Khat + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Khella with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, khella might have additive adverse effects on the liver when used with hepatotoxic drugs.

Full Khella + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Kinetin with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that kinetin inhibits human platelet aggregation and activation.

Full Kinetin + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Kiwi with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Clinical research suggests that kiwi inhibits platelet aggregation.

Full Kiwi + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Kratom with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the risk for adverse CNS depressant effects.

Full Kratom + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Krill Oil with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Krill Oil + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take L-arginine with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of...

Full L-arginine + Aspirin, Caffeine, Phenacetin, Propoxyphene answer

Can you take Lemon Balm with Aspirin, Caffeine, Phenacetin, Propoxyphene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.

Full Lemon Balm + Aspirin, Caffeine, Phenacetin, Propoxyphene answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Aspirin, Caffeine, Phenacetin, Propoxyphene is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aspirin, Caffeine, Phenacetin, Propoxyphene, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Aspirin, Caffeine, Phenacetin, Propoxyphene sits in 20 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Cytochrome P450 1A2 (Cyp1A2) Substrates 79 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

79 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Cns Depressants 78 ingredients

Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.

78 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

60 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Stimulant Drugs 44 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

44 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Hepatotoxic Drugs 38 ingredients

Medications with known liver considerations. Supplements that can stress the liver add to the load.

38 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Aspirin 22 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

22 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Caffeine 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Methylxanthines 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Narcotic Drugs 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Cytochrome P450 2D6 (Cyp2D6) Inhibitors 3 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

3 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Phenacetin 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Cytochrome P450 1A2 (Cyp1A2) Substrates 1 ingredient

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

1 of the supplement ingredient on this page reaches Aspirin, Caffeine, Phenacetin, Propoxyphene through this category.

Related: does Aspirin, Caffeine, Phenacetin, Propoxyphene deplete any nutrients?

Aspirin, Caffeine, Phenacetin, Propoxyphene has 5 reported nutrient associations in the research literature — see the Aspirin, Caffeine, Phenacetin, Propoxyphene nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Aspirin, Caffeine, Phenacetin, Propoxyphene

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aspirin, Caffeine, Phenacetin, Propoxyphene.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

Aspirin, Caffeine, Phenacetin, Propoxyphene & Supplements: Common Questions

What supplements interact with Aspirin, Caffeine, Phenacetin, Propoxyphene?
More than you might expect — 414 in total, though they are far from equal: 17 are rated major, 350 moderate, and 47 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Beer, Grapefruit, Siberian Cocklebur.
Which Aspirin, Caffeine, Phenacetin, Propoxyphene supplement interactions are the most serious?
Focus on the major group: Beer, Grapefruit, Siberian Cocklebur, Wine and 1,4-butanediol, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Aspirin, Caffeine, Phenacetin, Propoxyphene?
Usually yes — most people on Aspirin, Caffeine, Phenacetin, Propoxyphene can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Margesic Comp. 65 have the same supplement interactions as Aspirin, Caffeine, Phenacetin, Propoxyphene?
Yes — Margesic Comp. 65 all contain Aspirin, Caffeine, Phenacetin, Propoxyphene, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Aspirin, Caffeine, Phenacetin, Propoxyphene deplete any vitamins or nutrients?
It might — Aspirin, Caffeine, Phenacetin, Propoxyphene has 5 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Aspirin, Caffeine, Phenacetin, Propoxyphene nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Aspirin, Caffeine, Phenacetin, Propoxyphene and my other medications?
This page covers Aspirin, Caffeine, Phenacetin, Propoxyphene against supplements and herbal ingredients. Checking Aspirin, Caffeine, Phenacetin, Propoxyphene against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 18, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.