Medication interaction hub

What Supplements Interact with Olodaterol Hydrochloride, Tiotropium Bromide?

Olodaterol Hydrochloride, Tiotropium Bromide brand name: Stiolto Respimat. Every interaction below applies to the brands too.

171 Interactions 9 Major 133 Moderate 29 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Olodaterol Hydrochloride, Tiotropium Bromide? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Olodaterol Hydrochloride, Tiotropium Bromide against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

171 supplements and herbal ingredients have interactions with Olodaterol Hydrochloride, Tiotropium Bromide on file in the HelloPharmacist interaction database — 9 rated major, 133 moderate, and 29 minor. The most serious involve Grapefruit, Arsenic, Cesium, Ephedra and Henbane.

Our assessment: with 9 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Olodaterol Hydrochloride, Tiotropium Bromide.

Major 9 Moderate 133 Minor 29 No known interaction 1,281

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Olodaterol Hydrochloride, Tiotropium Bromide: Top Interactions at a Glance

The Olodaterol Hydrochloride, Tiotropium Bromide supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 171 interacting ingredients — plus 1,281 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Olodaterol Hydrochloride, Tiotropium Bromide Combinations Today

The Olodaterol Hydrochloride, Tiotropium Bromide + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Phosphatidylserine + Olodaterol Hydrochloride, Tiotropium Bromidei

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Read the full interaction Moderate Likelihood Possible American Elder + Olodaterol Hydrochloride, Tiotropium Bromidei

Theoretically, taking American elder might increase levels of CYP3A4 substrates.

Read the full interaction Moderate Likelihood Possible Goldthread + Olodaterol Hydrochloride, Tiotropium Bromidei

There's very preliminary evidence that berberine, a constituent of goldthread, might inhibit cytochrome P450 3A4 (CYP3A4) enzyme.

Read the full interaction Moderate Likelihood Possible Strawberry + Olodaterol Hydrochloride, Tiotropium Bromidei

In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux.

Read the full interaction Major Likelihood Likely Grapefruit + Olodaterol Hydrochloride, Tiotropium Bromidei

Grapefruit juice can increase levels of drugs metabolized by CYP3A4.

Read the full interaction Major Likelihood Probable Arsenic + Olodaterol Hydrochloride, Tiotropium Bromidei

Arsenic trioxide can prolong the QT interval.

Read the full interaction
The complete list

Every Supplement Checked Against Olodaterol Hydrochloride, Tiotropium Bromide

All 1,452 ingredients in our database, ranked by severity — 171 with a Olodaterol Hydrochloride, Tiotropium Bromide interaction on file and 1,281 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Olodaterol Hydrochloride, Tiotropium Bromide?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Phosphatidylserine with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Full Phosphatidylserine + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take American Elder with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking American elder might increase levels of CYP3A4 substrates.

Full American Elder + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Goldthread with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There's very preliminary evidence that berberine, a constituent of goldthread, might inhibit cytochrome P450 3A4 (CYP3A4) enzyme.

Full Goldthread + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Strawberry with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux.

Full Strawberry + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Diosmin with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, diosmin might inhibit the metabolism of CYP3A4 substrates.

Full Diosmin + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Echinacea with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.

Full Echinacea + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Eleuthero with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, eleuthero might increase levels of P-glycoprotein substrates.

Full Eleuthero + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Eucalyptus with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.

Full Eucalyptus + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take European Barberry with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.

Full European Barberry + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take European Mandrake with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concurrent use may cause additive anticholinergic effects and adverse effects.

Full European Mandrake + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Evodia with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, evodia might have an additive effect with drugs that prolong the QT interval, potentially increasing the risk of ventricular...

Full Evodia + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take False Unicorn with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.

Full False Unicorn + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Fennel with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.

Full Fennel + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Feverfew with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.

Full Feverfew + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Fo-ti with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fo-ti might increase the levels and clinical effects of drugs metabolized by CYP3A4.

Full Fo-ti + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Garlic with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.

Full Garlic + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take German Chamomile with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.

Full German Chamomile + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Ginger with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Ginger might increase or decrease the levels of CYP3A4 substrates.

Full Ginger + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Ginkgo with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, ginkgo might decrease levels of drugs metabolized by CYP3A4.

Full Ginkgo + Olodaterol Hydrochloride, Tiotropium Bromide answer

Can you take Goji with Olodaterol Hydrochloride, Tiotropium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.

Full Goji + Olodaterol Hydrochloride, Tiotropium Bromide answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Olodaterol Hydrochloride, Tiotropium Bromide is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Olodaterol Hydrochloride, Tiotropium Bromide, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Olodaterol Hydrochloride, Tiotropium Bromide sits in 5 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Olodaterol Hydrochloride, Tiotropium Bromide through this category.

P-Glycoprotein Substrates 37 ingredients

A drug-transport group: these medications are moved in and out of cells by the P-glycoprotein pump. Supplements that affect the pump can change how much of the drug is absorbed or kept in the body.

37 of the supplement ingredients on this page reach Olodaterol Hydrochloride, Tiotropium Bromide through this category.

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Olodaterol Hydrochloride, Tiotropium Bromide through this category.

Beta-Adrenergic Agonists 15 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

15 of the supplement ingredients on this page reach Olodaterol Hydrochloride, Tiotropium Bromide through this category.

Qt Interval-Prolonging Drugs 13 ingredients

Medications that can affect the heart's electrical rhythm (the QT interval). Supplements with similar effects can add to that risk.

13 of the supplement ingredients on this page reach Olodaterol Hydrochloride, Tiotropium Bromide through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Olodaterol Hydrochloride, Tiotropium Bromide

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Olodaterol Hydrochloride, Tiotropium Bromide.

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Pharmacist Counseling Corner

Olodaterol Hydrochloride, Tiotropium Bromide & Supplements: Common Questions

What supplements interact with Olodaterol Hydrochloride, Tiotropium Bromide?
More than you might expect — 171 in total, though they are far from equal: 9 are rated major, 133 moderate, and 29 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Grapefruit, Arsenic, Cesium.
Which Olodaterol Hydrochloride, Tiotropium Bromide supplement interactions are the most serious?
Focus on the major group: Grapefruit, Arsenic, Cesium, Ephedra and Henbane, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Olodaterol Hydrochloride, Tiotropium Bromide?
Usually yes — most people on Olodaterol Hydrochloride, Tiotropium Bromide can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Stiolto Respimat have the same supplement interactions as Olodaterol Hydrochloride, Tiotropium Bromide?
Yes — Stiolto Respimat all contain Olodaterol Hydrochloride, Tiotropium Bromide, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Olodaterol Hydrochloride, Tiotropium Bromide and my other medications?
This page covers Olodaterol Hydrochloride, Tiotropium Bromide against supplements and herbal ingredients. Checking Olodaterol Hydrochloride, Tiotropium Bromide against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.