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Dietary supplement

1-Androl Ingredients & Drug Interactions

by Vintage Muscle

1-Androl label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 1-Androl against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

1-Androl is a dietary supplement by Vintage Muscle with 1 active ingredient. Its ingredients are commonly taken for muscle building, increasing strength, athletic performance.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 1-DHEA. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against 1-Androl by Vintage Muscle

Ask about any prescription or over-the-counter medication and we check it for interactions with 1-Androl by Vintage Muscle — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of 1-Androl by Vintage Muscle

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

1-Androl contains one active ingredient: 1-DHEA, a prohormone. Once you take it, your body converts it to 1-testosterone and other androgens — male-type hormones.

The product also contains inactive ingredients (propylene glycol, ethanol, and natural flavors) that help deliver the active compound.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient 1-androsterone product and its label doesn't state a use — see 1-androsterone's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on whether 1-DHEA improves athletic performance isn't established in the data we hold — we have insufficient reliable evidence to rate it. That means studies so far haven't been strong enough to say whether it works for that purpose.

The evidence, ingredient by ingredient 1-androsterone

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

1-DHEA is a hormone-altering compound with real health risks and very limited safety testing. The most common reported adverse effects are dyslipidemia (unhealthy cholesterol changes — increases in LDL of around 29 mg/dL and decreases in HDL of around 19 mg/dL), transaminitis (liver enzyme elevation), and renal dysfunction (kidney problems).

A 4-week study showed significant increases in serum creatinine and decreases in kidney filtration rate, with GFR dropping below normal range and suggesting renal impairment, though creatinine stayed within normal limits. 1-DHEA should not be used during pregnancy or while breastfeeding because of its hormone-altering nature and unknown risks to the baby.

Side effects, ingredient by ingredient 1-androsterone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — 1-androsterone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any testosterone products or other hormone-based medications with your pharmacist before taking 1-Androl — there's a moderate risk of compounded hormonal side effects on your mood, heart, kidneys, and liver.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

1-Androl is a prohormone supplement with very limited safety data and documented effects on cholesterol, liver enzymes, and kidney function. If you're considering it, talk to your pharmacist or doctor first — especially if you take any testosterone-based medications or have a history of heart, kidney, or liver problems.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 1-Androl, straight from the product label.

Brand Vintage Muscle
Net contents 30 mL
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 304922
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 1-Androl by Vintage Muscle, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
IngredientAmount% DV
1-DHEA100 mg--

Other ingredients: Propylene Glycol, Ethanol, Natural Flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

1-DHEA

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

1-Androl by Vintage Muscle label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

1-Androl label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 1-Androl by Vintage Muscle

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

1-DHEA

Interacts with
8 drugs
100 mg per serving

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe o...

1-DHEA monograph & interactions

Other (inactive) ingredients: Propylene Glycol, Ethanol, Natural Flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

1-Androl by Vintage Muscle Drug Interactions

Want to check YOUR meds against 1-Androl?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
8Drugs
8 Moderate

Ingredients driving the most interactions

1-DHEA 8

Individual Drug Interactions

The ingredients in 1-Androl interact with 8 drugs. Click any drug to see the details.

1 of the 1 ingredient in 1-Androl interact with drugs. Each result below shows which ingredient is responsible. 1-DHEA

Each ingredient & the kinds of drugs it affects

For each ingredient in 1-Androl with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

1-DHEA1 drug type · 8 drugs

Testosterone

Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion.

Likelihood Possible Evidence D
1-DHEA full monograph & interactions
The maker

Brand information

Manufacturer and brand details for 1-Androl, from the product label.

Vintage Muscle

See all Vintage Muscle products
Name
Vintage Muscle
Street Address
50 W Broad Way Street 333, #94501
City
Salt Lake City
State
Utah
ZipCode
84101
Pharmacist Counseling Corner

1-Androl by Vintage Muscle: Common Questions

Does 1-Androl by Vintage Muscle interact with any medications?
Yes. Based on its ingredients, 1-Androl has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
1-Androl contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No. 1-DHEA is a hormone-altering prohormone and should not be used during pregnancy because of the health risks.
Is it safe while breastfeeding?
No. You should avoid 1-DHEA while breastfeeding because of unknown hormonal risks to the baby.
What are the main side effects?
The most common reported effects are unhealthy cholesterol changes (higher LDL, lower HDL), liver enzyme elevation, and kidney problems — including reduced kidney function. There's limited safety data overall, so other effects may occur.
Does it actually work for building muscle or athletic performance?
The evidence isn't established — we have insufficient reliable evidence to rate whether 1-DHEA improves athletic performance.
Why is this product liquid instead of a pill?
The product facts don't say. Your pharmacist or the manufacturer can explain the form choice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 1-Androl is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

1-Androl label
Go deeper

The Full Monographs Behind 1-Androl’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

1-androsterone

Interacts with 8 drugs

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It...

Read the full 1-androsterone monograph →
Sources

Sources & How We Checked

1-Androl's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

1-androsterone 2 references
  1. Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
  2. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

See these in context on the 1-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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