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Dietary supplement

Activated Charcoal Ingredients & Drug Interactions

by Natures Craft

Activated Charcoal label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Activated Charcoal against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Activated Charcoal is a dietary supplement by Natures Craft with 1 active ingredient. Its ingredients are commonly taken for poisoning and drug overdose (in emergency care), gas and bloating, upset stomach.Based on those ingredients, 2,027 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Activated Charcoal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Activated Charcoal by Natures Craft

Ask about any prescription or over-the-counter medication and we check it for interactions with Activated Charcoal by Natures Craft — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Activated Charcoal by Natures Craft

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: activated charcoal, which works by binding to substances in your stomach and intestines. The capsule also contains several inactive ingredients — cellulose ethers, rice flour, and MCT fractionated coconut oil — which help form and fill out the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Activated Charcoal's overall clinical evidence instead.

Moderate

Some clinical evidence supports Activated Charcoal for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Poisoning — rated "Possibly Effective" (Natural Medicines).

Activated charcoal has possibly effective evidence for poisoning treatment, which is its most established use. For other purposes — including high blood phosphate levels (hyperphosphatemia), wound healing, indigestion (dyspepsia), hangover relief, and high cholesterol — the evidence in our data is insufficient to establish whether it works.

Talk to your pharmacist or doctor about whether it's right for what you're hoping to treat.

The evidence, ingredient by ingredient Activated Charcoal

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth, activated charcoal is generally well tolerated for short-term use, but it commonly causes constipation — the most frequent side effect — along with black stools, belly pain, bloating, and gas. These effects are usually temporary.

Rarely, it can cause a blockage in your digestive tract. Safety data for pregnancy is limited; if you're pregnant or planning to become pregnant, use it only under medical guidance.

Because long-term routine use hasn't been well studied, check with your doctor or pharmacist before taking it regularly.

Side effects, ingredient by ingredient Activated Charcoal

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Activated Charcoal.
  • The most serious interaction on file is rated Major.
  • For scale: 2,028 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check any oral medications you're on — activated charcoal can reduce how well many of them work. If you're taking oral contraceptives (birth control), that's especially important because charcoal may lower their effectiveness.

Avoid taking them close together in time. If you drink alcohol regularly, know that it can weaken charcoal's binding action.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Activated charcoal is a single-ingredient supplement most established for poisoning treatment. Its major drawback is that it can significantly reduce absorption of many medications — including birth control pills — so if you take any prescriptions or oral contraceptives, you must check them against this product first.

It's generally well tolerated short-term but causes constipation in most people.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Activated Charcoal, straight from the product label.

Brand Natures Craft
Net contents 90 Veggie Capsule(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 256305
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Activated Charcoal by Natures Craft, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetable Capsule(s)
Maximum serving Sizes:
2 Vegetable Capsule(s)
Servings per container
45
IngredientAmount% DV
Activated Charcoal1100 mg--

Other ingredients: Cellulose Ethers, Rice Flour, MCT fractionated Coconut Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one (1) veggie capsule twice a day. This product should be taken 2-3 hours before taking other medications.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Nature at its finest

Please recycle.

Formulation

Derived from coconut shells Natural absorbent Natural digestion support

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Formulated in the U.S.A. Good Manufacturing Practice Sourced from a GMP Certified Facility Quality Assured

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Activated Charcoal by Natures Craft label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Activated Charcoal label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Activated Charcoal by Natures Craft

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Activated Charcoal

Interacts with
2,027 drugs
1100 mg per serving Form: Coconut

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings...

Activated Charcoal monograph & interactions

Other (inactive) ingredients: Cellulose Ethers, Rice Flour, MCT fractionated Coconut Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Activated Charcoal by Natures Craft Drug Interactions

Want to check YOUR meds against Activated Charcoal?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,027Drugs
2,022 Major 5 Moderate

Ingredients driving the most interactions

Activated Charcoal 2,027

Individual Drug Interactions

The ingredients in Activated Charcoal interact with 2,027 drugs. Click any drug to see the details.

1 of the 1 ingredient in Activated Charcoal interact with drugs. Each result below shows which ingredient is responsible. Activated Charcoal

Each ingredient & the kinds of drugs it affects

For each ingredient in Activated Charcoal with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Activated Charcoal3 drug types · 2,027 drugs

Oral Drugs

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.

Likelihood Probable Evidence B
Alcohol (Ethanol)

The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.

Likelihood Probable Evidence D
Contraceptive Drugs

Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.

Likelihood Possible Evidence B
Activated Charcoal full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Activated Charcoal, from the product label.

Natures Craft

See all Natures Craft products
Name
Nature's Craft
City
Monsey
State
NY
ZipCode
10952
Phone Number
408-599-3841
Web Address
shopnaturescraft.com
Pharmacist Counseling Corner

Activated Charcoal by Natures Craft: Common Questions

Does Activated Charcoal by Natures Craft interact with any medications?
Yes. Based on its ingredients, Activated Charcoal has a known interaction with 2,027 medications, including 2022 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Activated Charcoal contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will activated charcoal interfere with my birth control?
Possibly. Activated charcoal can bind to oral contraceptives and reduce how much your body absorbs, which may lower how well they protect you. The risk is higher if you take them close together in time. Talk with your pharmacist about spacing them out, or ask about using a backup method.
What are the most common side effects?
Constipation is by far the most common complaint, but black stools, belly pain, bloating, and gas also happen. These effects are usually temporary. Rarely, activated charcoal can cause a blockage in your digestive tract.
Is activated charcoal safe to use during pregnancy?
The safety data for pregnancy is limited. It's rated possibly safe, but you shouldn't use it without medical guidance during pregnancy. Talk with your doctor or pharmacist for personalized advice.
Can I take activated charcoal with alcohol?
Alcohol can weaken activated charcoal's binding ability, so it may not work as intended if you drink. It's best to avoid using them together.
How does activated charcoal work?
Activated charcoal binds to substances in your stomach and intestines. This can prevent your body from absorbing certain things — which is useful for poisoning, but also means it can interfere with medications and other substances you want your body to absorb.
Does this product work for hangovers or high cholesterol?
The evidence for activated charcoal in those uses isn't established in our data. We only have possibly effective evidence for poisoning treatment. For other uses, talk with your pharmacist about what the science actually supports.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Activated Charcoal is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Activated Charcoal label
Go deeper

The Full Monographs Behind Activated Charcoal’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Activated Charcoal

Interacts with 2,027 drugs

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings and overdoses. For everyday uses like g...

Read the full Activated Charcoal monograph →
Sources

Sources & How We Checked

Activated Charcoal's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Activated Charcoal 14 references
  1. Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
  2. Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
  3. Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
  4. Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
  5. Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
  6. Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
  7. Wananukul W, Klaikleun S, Sriapha C, Tongpoo A. Effect of activated charcoal in reducing paracetamol absorption at supra-therapeutic dose. J Med Assoc Thai 2010;93(10):1145-9.
  8. Wang Z, Cui M, Tang L, et al. Oral activated charcoal suppresses hyperphosphataemia in haemodialysis patients. Nephrology (Carlton) 2012;17(7):616-20. PubMed
  9. Wang X, Mondal S, Wang J, et al. Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects. Am J Cardiovasc Drugs 2014;14(2):147-54. PubMed
  10. Chyka PA, Seger D, Krenzelok EP, et al. Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 2005;43(2):61-87. PubMed
  11. Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev 2018;2:CD003328. PubMed
  12. Elomaa K, Ranta S, Tuominen J, Lähteenmäki P. Charcoal treatment and risk of escape ovulation in oral contraceptive users. Hum Reprod. 2001;16(1):76-81. PubMed
  13. Gao Y, Wang G, Li Y, Lv C, Wang Z. Effects of oral activated charcoal on hyperphosphatemia and vascular calcification in Chinese patients with stage 3-4 chronic kidney disease. J Nephrol. 2019;32(2):265-72. PubMed
  14. Skov K, Graudal NA, Jürgens G. The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis. Basic Clin Pharmacol Toxicol 2021;128(4):568-578. PubMed

See these in context on the Activated Charcoal monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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