Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Serene Spirit Teapills Ingredients & Drug Interactions

by Plum Flower

Serene Spirit Teapills label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Serene Spirit Teapills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Serene Spirit Teapills is a dietary supplement by Plum Flower with 6 active ingredients. Its ingredients are commonly taken for anti-aging and longevity, hair graying and hair loss, general tonic for vitality.Based on those ingredients, 1,431 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Polygonum multiflorum Stem Extract, Ziziphus jujuba Fruit Extract, Poria cocos Sclerotium Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Serene Spirit Teapills by Plum Flower

Ask about any prescription or over-the-counter medication and we check it for interactions with Serene Spirit Teapills by Plum Flower — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Serene Spirit Teapills by Plum Flower

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (1,360 mg) without saying how much of each component you get.

Serene Spirit Teapills contains 6 ingredients. The active ones are extracts of fo-ti stem, wheatgrass fruit, poria mushroom sclerotium, zizyphus fruit, Lilium brownii bulb, and Albizia julibrissin bark — a blend used in traditional herbal practice.

The product also contains inactive ingredients including dextrin, hydrated magnesium silicate, activated carbon, China wax, and wheat.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Calming and sleep support.
  • We looked for evidence on: Anxiety, Insomnia, Stress, Irritability.
  • The closest evidence on file: Zizyphus is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Zizyphus is rated "Insufficient Reliable Evidence To Rate" for Insomnia.
  • Also on file: Poria Mushroom is rated "Insufficient Reliable Evidence To Rate" for Insomnia.

The evidence supporting Serene Spirit Teapills for its traditional uses is not established in the data we hold. For all the conditions mentioned in the research — including age-related cognitive decline, hair loss, Alzheimer disease, osteoporosis, and cardiovascular health — the effectiveness ratings for fo-ti, wheatgrass, poria mushroom, and zizyphus are all insufficient reliable evidence to rate.

This means the research hasn't yet proven or disproven whether it works for these purposes.

The evidence, ingredient by ingredient Fo-ti Wheatgrass Poria Mushroom Zizyphus Albizia Julibrissin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fo-ti carries the most serious safety concern: it has been linked to cases of liver injury, including around 450 documented cases of hepatitis in the medical literature, ranging from mild to cirrhosis or liver failure. Stomach upset — abdominal pain, diarrhea, nausea, and vomiting — is common, particularly with unprocessed fo-ti.

Wheatgrass is generally well tolerated as a food but can trigger allergic reactions in wheat-sensitive people; poria mushroom is generally well tolerated but has limited human safety data; and zizyphus fruit is widely eaten as food, though concentrated supplements haven't been well studied. The product is not recommended in pregnancy or while breastfeeding due to insufficient safety data — wheatgrass and poria mushroom safety in pregnancy and lactation is not established, zizyphus fruit is likely safe as food but medicinal doses are not well studied, and fo-ti, Lilium brownii, and Albizia are best avoided because safety is not established.

Side effects, ingredient by ingredient Fo-ti Wheatgrass Poria Mushroom Zizyphus Albizia Julibrissin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Zizyphus, Poria Mushroom, Fo-ti, Wheatgrass, Albizia Julibrissin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
  • For scale: 1,432 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking Serene Spirit if you use blood thinners (like warfarin), diabetes medications, sedatives or sleep aids, drugs that slow the central nervous system, diuretics (water pills), digoxin (a heart medication), sulindac (an anti-inflammatory), or any medication processed by liver enzymes — the product's fo-ti and other ingredients may change how these drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product blends traditional herbal ingredients with limited scientific evidence of effectiveness and a documented risk of liver injury from fo-ti. It's not right for anyone taking blood thinners, diabetes medications, sedatives, or drugs that depend on liver enzymes to work — and it should be avoided in pregnancy and while breastfeeding.

If you're considering it, talk with your doctor or pharmacist first to review your medications and whether this product is appropriate for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Serene Spirit Teapills, straight from the product label.

Brand Plum Flower
Barcode (UPC) 739934833834
Net contents 1.2 Ounce(s); 34 Gram(s); 200 Pill(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 310587
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Serene Spirit Teapills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8 Pill(s)
Maximum serving Sizes:
8 Pill(s)
Servings per container
25
UPC/BARCODE
739934833834
IngredientAmount% DV
Proprietary Extract Blend1360 mg--
Polygonum multiflorum Stem Extract0 NP--
Triticum aestivum Fruit Extract0 NP--
Poria cocos Sclerotium Extract0 NP--
Ziziphus jujuba Fruit Extract0 NP--
Lilium brownii Bulb Extract0 NP--
Albizia julibrissin Bark Extract0 NP--

Other ingredients: Dextrin, Magnesium Silicate, Hydrated, Carbon, Activated, China Wax, Wheat

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Gan Mai Da Zao Wan

Foci Pharmaceutical 1929

FDA Statement of Identity

Herbal Supplement

Precautions

Contains wheat

Caution during pregnancy

Keep out of reach of children

Suggested/Recommended/Usage/Directions

Take 8 pills 3 times daily or as directed by your health care practitioner

Formulation

US owned & operated since 1969. Made in China in partnership with the award winning Lanzhou Foci Pharmaceutical Co. Ltd.

No pharmaceuticals or dyes Unsulfured

Plum Flower Quality Guarantee Preservative-free herbs when available Scientifically authenticated herbs Microbial and heavy metal tested Produced at a Good Manufacturing Practices (GMP) certified factory

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Serene Spirit Teapills by Plum Flower label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Serene Spirit Teapills label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Serene Spirit Teapills by Plum Flower

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size8 Pill(s) Dosage formTablet Or Pill Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Blend

1360 mg per serving

Other (inactive) ingredients: Dextrin, Magnesium Silicate, Hydrated, Carbon, Activated, China Wax, Wheat. These complete the product’s ingredient list but are not active constituents.

Interaction report

Serene Spirit Teapills by Plum Flower Drug Interactions

Want to check YOUR meds against Serene Spirit Teapills?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,431Drugs
1,431 Moderate

Ingredients driving the most interactions

Polygonum multiflorum Stem Extract 1,259
Ziziphus jujuba Fruit Extract 469
Poria cocos Sclerotium Extract 417
Triticum aestivum Fruit Extract 272
Albizia julibrissin Bark Extract 248

Individual Drug Interactions

The ingredients in Serene Spirit Teapills interact with 1,431 drugs. Click any drug to see the details.

5 of the 6 ingredients in Serene Spirit Teapills interact with drugs. Each result below shows which ingredient is responsible. Polygonum multiflorum Stem Extract Ziziphus jujuba Fruit Extract Poria cocos Sclerotium Extract Triticum aestivum Fruit Extract Albizia julibrissin Bark Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Serene Spirit Teapills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Polygonum multiflorum Stem Extract17 drug types · 1,259 drugs

Anticoagulant/Antiplatelet Drugs

Fo-ti has been linked to cases of acute liver failure which can decrease clotting factor production and increase the effects of anticoagulants. In one case, a patient who had been stable on warfarin presented with acute hepatitis and an INR elevated to 14.98. The patient had been taking fo-ti for 90 days prior to admission. Discontinuation of warfarin and fo-ti lead to a decrease in the INR and full recovery. Theoretically, concomitant use of fo-ti with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients. Until more is known, monitor patients taking fo-ti and drugs that affect bleeding.
Some of these drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), dipyridamole (Persantine), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, fo-ti might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Fo-ti reportedly has hypoglycemic effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, taking large amounts of fo-ti might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro research suggests that fo-ti extract has estrogenic activity.

Likelihood Probable Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, fo-ti might increase or decrease the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research suggests that fo-ti might inhibit CYP1A2. Additionally, in vitro research suggests that the degree of CYP1A2 inhibition depends on the type of fo-ti extract (i.e., the raw plant leads to greater inhibition than extensively processed extracts). However, in an animal study, an aqueous extract of fo-ti inhibited CYP1A2 while an alcoholic extract of fo-ti induced CYP1A2. Induction or inhibition of CYP1A2 by fo-ti has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, fo-ti might increase the levels and clinical effects of drugs metabolized by CYP2B6.
Animal research suggests that fo-ti might inhibit CYP2B6. One in vitro study suggests that the degree of CYP2B6 inhibition may depend on the type of fo-ti extract (i.e., the raw plant leads to greater inhibition than extensively processed extracts). However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2C19.
Animal and in vitro research suggests that fo-ti may inhibit CYP2C19. An in vitro study suggests that the degree of CYP2C19 inhibition may depend on the type of fo-ti extract (i.e., the raw plant leads to greater inhibition than extensively processed extracts). However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, fo-ti might increase the levels and clinical effects of drugs metabolized by CYP2C8.
In vitro research suggests that fo-ti might inhibit CYP2C8. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2C9.
Animal and in vitro research suggests that fo-ti may inhibit CYP2C9. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2D6.
Animal research suggests that fo-ti might inhibit CYP2D6. Additionally, an in vitro study suggests that the degree of CYP2D6 inhibition may depend on the type of fo-ti extract (i.e., the raw plant leads to greater inhibition than extensively processed extracts). However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, fo-ti might increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research suggests that fo-ti might inhibit CYP3A4. One in vitro study suggests that the degree of CYP3A4 inhibition may depend on the type of fo-ti extract (i.e., the raw plant leads to greater inhibition than extensively processed extracts). However, this evidence conflicts with animal research suggesting that fo-ti does not inhibit CYP3A4. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, fo-ti, particularly raw fo-ti root, might increase the risk of hypokalemia and cardiotoxicity when taken with digoxin.
Raw fo-ti root contains anthraquinone derivatives, which might have stimulant laxative effects. In vitro research shows that fermented and processed fo-ti root have reduced laxative effects compared with raw fo-ti root.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, fo-ti, particularly raw fo-ti root, might increase the risk of hypokalemia when taken with diuretic drugs.
Raw fo-ti root contains anthraquinone derivatives, which might have stimulant laxative effects and compound diuretic-induced potassium loss. In vitro research shows that fermented and processed fo-ti root have reduced laxative effects compared with raw fo-ti root.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking large amounts of fo-ti might interfere with hormone replacement therapy through competition for estrogen receptors.
In vitro research suggests that fo-ti extract has estrogenic activity.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, fo-ti might increase the risk of liver damage when taken with hepatotoxic drugs.
Fo-ti has been linked to liver damage in many reports.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, fo-ti, particularly raw fo-ti root, might increase the risk of fluid and electrolyte depletion when taken with stimulant laxatives.
Raw fo-ti root contains anthraquinone derivatives, which might have stimulant laxative effects. However, in vitro research shows that fermented and processed fo-ti root have reduced laxative effects compared with raw fo-ti root.

Likelihood Possible Evidence D
Sulindac (Clinoril)

Theoretically, fo-ti might increase or decrease the levels and clinical effects of sulindac.
Animal research suggests that the type of fo-ti extract might affect the levels of sulindac differently; the raw plant may increase levels, but processed parts may decrease levels. Induction or inhibition of CYP1A2 by fo-ti has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, fo-ti might increase the effects and adverse effects of warfarin.
Fo-ti may have stimulant laxative effects and cause diarrhea, especially when the raw or unprocessed fo-ti root is used. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Also, fo-ti has been linked to cases of acute liver failure which can decrease clotting factor production and increase the effects of warfarin. In one case, a patient who had been stable on warfarin presented with acute hepatitis and an INR elevated to 14.98. The patient had been taking fo-ti for 90 days prior to admission. Discontinuation of warfarin and fo-ti lead to a decrease in the INR and full recovery.

Likelihood Possible Evidence D
Polygonum multiflorum Stem Extract full monograph & interactions

Ziziphus jujuba Fruit Extract3 drug types · 469 drugs

Antidiabetes Drugs

Theoretically, zizyphus might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that zizyphus has hypoglycemic activity. However, a small clinical study shows that zizyphus fruit powder does not reduce fasting blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, zizyphus might cause additive sedative effects when taken with CNS depressants.
Some animal research has found that various parts of zizyphus have sedative effects. However, other animal research shows that zizyphus plant extract does not alter sleep parameters when used in combination with pentobarbital.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, zizyphus might decrease the levels and clinical effects of drugs metabolized by CYP1A2.
Animal research shows that zizyphus induces CYP1A2 enzymes. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Ziziphus jujuba Fruit Extract full monograph & interactions

Poria cocos Sclerotium Extract3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Poria cocos Sclerotium Extract full monograph & interactions

Triticum aestivum Fruit Extract2 drug types · 272 drugs

Antidiabetes Drugs

Theoretically, taking wheatgrass with antidiabetes drugs might lower blood glucose levels and increase the risk of hypoglycemia.
Animal research shows that taking wheatgrass stimulates the release of insulin from beta-cells and lowers blood glucose.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that wheatgrass induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Triticum aestivum Fruit Extract full monograph & interactions

Albizia julibrissin Bark Extract1 drug type · 248 drugs

Cns Depressants

Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice. Theoretically, Albizia julibrissin might enhance the therapeutic and adverse effects of CNS depressants.
Some CNS depressants include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), clonazepam (Klonopin), lorazepam (Ativan), zolpidem (Ambien), and others.

Likelihood Possible Evidence D
Albizia julibrissin Bark Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Serene Spirit Teapills, from the product label.

Plum Flower

Name
Mayway Herbs
City
Oakland
State
CA
Web Address
www.plumflowerherbs.com
Pharmacist Counseling Corner

Serene Spirit Teapills by Plum Flower: Common Questions

Does Serene Spirit Teapills by Plum Flower interact with any medications?
Yes. Based on its ingredients, Serene Spirit Teapills has a known interaction with 1,431 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Serene Spirit Teapills contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
No. Safety is not established for any of the main ingredients during pregnancy or breastfeeding, and fo-ti is rated possibly unsafe for both. Talk with your doctor or pharmacist before use if you're pregnant, planning to become pregnant, or breastfeeding.
What's fo-ti and why is it a concern?
Fo-ti is the stem extract of Polygonum multiflorum, used traditionally for aging-related concerns. It's been linked to serious liver injury in around 450 documented cases, including one patient on blood thinners who developed acute hepatitis. The facts show it can amplify blood thinners and interact with many other drugs.
Can I take this with my blood thinner (warfarin)?
No — fo-ti can reduce clotting factors and dangerously increase warfarin's effects. One documented case showed a patient's INR (a measure of bleeding risk) jump to 14.98 after 90 days of fo-ti. Do not combine these without explicit approval and close monitoring from your doctor.
What are the most common side effects?
Stomach upset — abdominal pain, diarrhea, nausea, and vomiting — is common, especially with unprocessed fo-ti. Wheatgrass can cause allergic reactions, nausea, loss of appetite, or constipation. Rare but serious: liver damage has been reported with both processed and unprocessed fo-ti.
Will this help with memory or aging?
The evidence isn't established in the data we hold. For all the traditional uses of these ingredients — memory, cognitive decline, Alzheimer disease, skin aging, and others — the research so far is insufficient to rate whether they work.
Is there wheat in this product?
Yes. Wheatgrass (one of the active ingredients) is wheat, and wheat is also listed in the inactive ingredients. If you have a wheat allergy, do not take this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Serene Spirit Teapills label
Go deeper

The Full Monographs Behind Serene Spirit Teapills’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fo-ti

Interacts with 1,259 drugs

Fo-ti (He Shou Wu) is a root used in traditional Chinese medicine, often promoted for healthy aging and hair. High-quality human evidence for these benefits is limited, and processed Fo-ti h...

Read the full Fo-ti monograph → Herb & supplement monograph

Wheatgrass

Interacts with 272 drugs

Wheatgrass is the young grass of the wheat plant, taken as a juice or powder, and is mainly used as a concentrated source of vitamins and plant nutrients. Solid scientific evidence for most...

Read the full Wheatgrass monograph → Herb & supplement monograph

Poria Mushroom

Interacts with 417 drugs

Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...

Read the full Poria Mushroom monograph → Herb & supplement monograph

Zizyphus

Interacts with 469 drugs

Zizyphus (jujube) is an edible fruit and traditional remedy used mainly for sleep, anxiety, and digestion. The fruit is a nutritious food, but human evidence for its medicinal benefits is li...

Read the full Zizyphus monograph → Herb & supplement monograph

Albizia Julibrissin

Interacts with 248 drugs

Albizia julibrissin (Persian silk tree, He Huan) is a plant used in traditional Chinese medicine, mainly the flower and bark, for calming the mind, lifting mood, and easing sleep problems. H...

Read the full Albizia Julibrissin monograph →
Sources

Sources & How We Checked

Serene Spirit Teapills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 52 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fo-ti 28 references
  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  5. Park GJ, Mann SP, Ngu MC. Acute hepatitis induced by Shou-Wu-Pian, a herbal product derived from Polygonum multiflorum. J Gastroenterol Hepatol 2001;16:115-7.
  6. But PP, Tomlinson B, Lee KL. Hepatitis related to the Chinese medicine Shou-wu-pian manufactured from Polygonum multiflorum. Vet Hum Toxicol 1996;38:280-2.
  7. Oerter Klein KO, Janfaza M, Wong JA, Chang RJ. Estrogen bioactivity in Fo-Ti and other herbs used for their estrogen-like effects as determined by a recombinant cell bioassay. J Clin Endocrinol Metab 2003;88:4077-9.. PubMed
  8. Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
  9. UK Medicines and Healthcare Products Regulatory Agency. Polygonum multiflorum and liver reactions. April 2006. Available at: www.mhra.gov.uk/home/idcplg?IdcService= SS_GET_PAGE&useSecondary=true&ssDocName= CON2023590&ssTargetNodeId= 833 (Accessed 10 May 2
  10. Panis B, Wong DR, Hooymans PM, De Smet PA, Rosias PP. Recurrent toxic hepatitis in a Caucasian girl related to the use of Shou-Wu-Pian, a Chinese herbal preparation. J Pediatr Gastroenterol Nutr 2005;41:256-8. PubMed
  11. Mazzanti G, Battinelli L, Daniele C, et al. New case of acute hepatitis following the consumption of Shou Wu Pian, a Chinese herbal product derived from Polygonum multiflorum. Ann Intern Med 2004;140:E589-90.
  12. Cardenas A, Restrepo JC, Sierra F, Correa G. Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum. J Clin Gastroenterol 2006;40:629-32. PubMed
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Wheatgrass 5 references
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Poria Mushroom 3 references
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Albizia Julibrissin 1 reference
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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