Alfa 369 Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Alfa 369 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Alfa 369 is a dietary supplement by Alfa Vitamins with 1 active ingredient. Its ingredients are commonly taken for source of omega-3 (ala) fatty acids, heart and cholesterol health, dry skin and inflammation.Based on those ingredients, 379 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Flaxseed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Alfa 369 by Alfa Vitamins
Ask about any prescription or over-the-counter medication and we check it for interactions with Alfa 369 by Alfa Vitamins — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Alfa 369 by Alfa Vitamins
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Alfa 369 contains 5 active ingredients, all fatty acids and related compounds: polyunsaturated fat, linoleic acid, oleic acid, alpha-linolenic acid, and organic flaxseed oil (which is a blend of component fatty acids). These are all plant-based fats.
The product also contains inactive ingredients — gelatin, glycerin, caramel color, and purified water — that serve as the capsule and carrier.
Does it work?
Moderate evidence
Oleic acid, one of this product's active ingredients, is rated possibly effective for high cholesterol (hypercholesterolemia) and for coronary heart disease (CHD). The evidence base for the other fatty acids in this product isn't established in the data we hold.
How safe is it?
Some data gaps
Oleic acid is generally recognized as safe when consumed in normal amounts from foods like olive oil. However, concentrated supplements haven't been well studied in pregnancy or during breastfeeding — food amounts are fine, but supplement-level doses lack good safety data.
If you're pregnant, nursing, or planning to be, talk with your doctor or pharmacist about whether this product is right for you.
Meds to double-check
Moderate interaction found
If you take any antidiabetes drugs or blood sugar–lowering medications (oral hypoglycemic drugs), double-check this product with your pharmacist or doctor before starting — oleic acid may increase how much they lower your blood sugar. For the other ingredients we couldn't check the data on, use the medication interaction tool on this page with your exact prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.
Alfa 369 may be worth considering if you're interested in oleic acid for cholesterol or heart health — the evidence is preliminary but encouraging. If you take any blood sugar–lowering medication, check with us or your doctor first, since oleic acid might boost their effect.
Anyone pregnant, nursing, or taking regular medications should run their list through our checker or ask your pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Alfa 369, straight from the product label.
| Brand | Alfa Vitamins |
|---|---|
| Barcode (UPC) | 676194173174 |
| Net contents | 100 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Sep 24, 2019 |
| DSLD ID | 206723 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Alfa 369 by Alfa Vitamins, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Calories from Fat | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 2% |
| Polyunsaturated Fat | 0.5 Gram(s) | -- |
| Linoleic Acid | 125 mg | -- |
| Oleic Acid | 140 mg | -- |
| Alpha-Linolenic Acid | 500 mg | -- |
| organic Flaxseed Oil | 1000 mg | -- |
| Other Fatty Acids and Phytonutrients | 72 mg | -- |
Other ingredients: Gelatin, Glycerin, Caramel color, purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Adults - Take one (1) softgel daily, as a dietary supplement, preferably with a meal.
Storage
Important: Store tightly closed in a dry place at controlled room temperature of 59(0)-86(0)F.
Precautions
Do not use if safety seal is broken or missing.
Keep out of reach of children.
Seals/Symbols
Made in USA #1 Satisfaction Guaranteed Quality
General Statements
Natural
Formula
Omega 369 Flax Oil 1000 mg
Formulation
Organic
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Alfa 369 by Alfa Vitamins label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Alfa 369 by Alfa Vitamins
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.
Organic Flaxseed Oil
Interacts with293 drugs
Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help s...
Organic Flaxseed Oil monograph & interactions- › Linoleic Acid
- › Oleic Acid
- › Alpha-Linolenic Acid
- › Other Fatty Acids and Phytonutrients
Other (inactive) ingredients: Gelatin, Glycerin, Caramel color, Purified Water. These complete the product’s ingredient list but are not active constituents.
Alfa 369 by Alfa Vitamins Drug Interactions
HelloPharmacist Interaction Report
Alfa 369 by Alfa Vitamins contains one ingredient with documented interactions: oleic acid, which may increase the effects of antidiabetes drugs (blood sugar–lowering medications).
In preliminary research, people with type 2 diabetes who ate a diet rich in oleic acid from olive oil had lower fasting blood glucose levels compared to those eating a diet high in linoleic acid. This means if you're taking oral antidiabetes medication, the combination could lower your blood sugar more than expected — something worth discussing with your doctor or pharmacist.
Read the full breakdown — every affected drug type, severity by severity
Three other ingredients in this product — polyunsaturated fat, linoleic acid, and alpha-linolenic acid — we could not check for interactions because we don't hold data on them. Flaxseed oil is a blend; its individual components are listed separately.
Altogether, these interactions span 85 individual medications.
Use the medication checker on this page to run through your exact prescriptions before you start, especially if you take any blood sugar–lowering drugs.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Alfa 369?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Alfa 369 interact with 379 drugs. Click any drug to see the details.
1 of the 1 ingredient in Alfa 369 interact with drugs. Each result below shows which ingredient is responsible. organic Flaxseed Oil
AbciximabReoPro
How Abciximab interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Organic Flaxseed Oil + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Alfa 369 — through 1 ingredient. Tap an ingredient for the detail:
Organic Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Organic Flaxseed Oil + Anacaulase-bcdb interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Alfa 369 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Flaxseed Oil
Anticoagulant/Antiplatelet Drugs
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Small clinical studies show that consuming flaxseed oil might decrease platelet aggregation and increase bleeding time.
Antihypertensive Drugs
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Some clinical evidence suggests that long-term consumption of flaxseed oil can modestly lower systolic and diastolic blood pressure, while other clinical research shows no effect.
Ezetimibe (Zetia)
Concomitant use of flaxseed oil and ezetimibe reduces the absorption of alpha-linolenic acid from flaxseed oil.
In one clinical study, concomitant consumption of ezetimibe 10 mg daily with flaxseed oil 2 grams providing 1 gram of alpha-linolenic acid daily blocked the absorption of alpha-linolenic acid, resulting in an overall reduction in alpha-linolenic plasma levels from baseline.
Brand information
Manufacturer and brand details for Alfa 369, from the product label.
Alfa Vitamins
See all Alfa Vitamins products- Name
- Alfa Vitamins Laboratories, inc.
- Street Address
- 4701 NW 77th Avenue
- City
- Miami
- State
- FL
- ZipCode
- 33166
- Web Address
- alfavitamins.com
Alfa 369 by Alfa Vitamins: Common Questions
Does Alfa 369 by Alfa Vitamins interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is oleic acid, and why is it in this product?
Is oleic acid safe to take if I'm pregnant?
I take metformin for diabetes. Can I take this product?
Does Alfa 369 have any fillers?
What does the research say about oleic acid and cholesterol?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Alfa 369 is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Alfa 369’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Flaxseed Oil
Interacts with 293 drugsFlaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help support heart health and provide healthy...
Read the full Flaxseed Oil monograph → Herb & supplement monographOleic Acid
Interacts with 86 drugsOleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...
Read the full Oleic Acid monograph →Sources & How We Checked
Alfa 369's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Oleic Acid 19 references
- Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
- Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
- Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
- Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
- Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
- Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
- FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
- Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
- Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
- Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
- Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
- Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
- Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
- Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
- Ben Fradj MK, Ouanes Y, Hadj-Taieb S, et al. Decreased oleic acid and marine n?-?3 polyunsaturated fatty acids in Tunisian patients with urothelial bladder cancer. Nutr Cancer. 2018;70(7):1043-1050.
- de Silva PS, Luben R, Shrestha SS, Khaw KT, Hart AR. Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries. Eur J Gastroenterol Hepatol. 2014;26(1):11-8. PubMed
- Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. Lipids. 2001;36(1):1-6. PubMed
- Lin HC, van Citters GW, Heimer F, Bonorris G. Slowing of gastrointestinal transit by oleic acid: a preliminary report of a novel, nutrient-based treatment in humans. Dig Dis Sci. 2001;46(2):223-9. PubMed
- Li D, Tong Y, Li Y. Associations between dietary oleic acid and linoleic acid and depressive symptoms in perimenopausal women: The Study of Women's Health Across the Nation. Nutrition. 2020 Mar;71:110602. PubMed
Flaxseed Oil 21 references
- Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
- Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
- Nordstrom DC, Honkanen VE, Nasu Y, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Rheumatol Int 1995;14:231-4. PubMed
- De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
- Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
- Bloedon LT, Szapary PO. Flaxseed and cardiovascular risk. Nutr Rev 2004;62:18-27. DOI
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