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Dietary supplement

Alle-Relief Ingredients & Drug Interactions

by Eclectic Herb

Alle-Relief label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Alle-Relief against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Alle-Relief is a dietary supplement by Eclectic Herb with 3 active ingredients. Its ingredients are commonly taken for enlarged prostate (bph) symptoms, seasonal allergies, joint pain and arthritis.Based on those ingredients, 284 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Nettle, Mullein, Eyebright. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Alle-Relief by Eclectic Herb

Ask about any prescription or over-the-counter medication and we check it for interactions with Alle-Relief by Eclectic Herb — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Alle-Relief by Eclectic Herb

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Alle-Relief has 3 active ingredients: nettle, mullein, and eyebright, all delivered as a liquid. The product also contains glycerin and filtered water as inactive ingredients.

These are traditional botanicals used for respiratory and allergy support, though the evidence for most is limited.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Sinus support for children.
  • We looked for evidence on: Allergic rhinitis (hay fever), Rhinosinusitis, Common cold, Conjunctivitis, Cough, Bronchitis — and 4 related terms.
  • The closest evidence on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Common cold, Cough, Pharyngitis, Rhinosinusitis, and more.
  • Also on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Bronchitis.

The evidence behind these ingredients is thin. Nettle is rated possibly effective for diabetes, but for everything else in this formula — allergies, asthma, cough — the evidence isn't established in the data we hold.

Mullein and eyebright have no established evidence for any of their traditional uses either. You're working mostly with tradition here, not solid clinical proof.

The evidence, ingredient by ingredient Stinging Nettle Mullein Eyebright

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken as directed, nettle and mullein are generally well tolerated in the short term, though human safety data are limited for mullein. The most common side effects from nettle are constipation and diarrhea.

Eyebright is likely safe as a tea in small amounts but has been reported to cause confusion, headache, nausea, constipation, cough, and nasal congestion. Nettle is not recommended during pregnancy or breastfeeding because of traditional concerns about the uterus and lack of safety data.

The same applies to mullein and eyebright — there isn't enough safety information for either pregnancy or breastfeeding, so talk with your doctor before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Stinging Nettle Mullein Eyebright

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Eyebright, Mullein, Stinging Nettle.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 284 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Alle-Relief, double-check if you take blood thinners like warfarin — nettle's vitamin K content can reduce how well they work. Also check diabetes medications (nettle and eyebright may lower blood sugar further), diuretics (nettle can amplify their effect), and lithium (nettle might raise its levels).

These are Moderate or Minor severity concerns, but they matter for your safety.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Alle-Relief is a traditional blend for allergies and respiratory symptoms, but its effectiveness isn't well established. The bigger issue is its interactions with blood thinners, diabetes drugs, diuretics, and lithium.

If you take any of those, check your specific medications with our tool before starting. If you're pregnant or breastfeeding, talk with your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alle-Relief, straight from the product label.

Brand Eclectic Herb
Barcode (UPC) 023363622078
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 316715
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Kosher, Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alle-Relief by Eclectic Herb, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL, 0.75 mL, 1 mL, 1.5 mL
Maximum serving Sizes:
0.5 mL, 0.75 mL, 1 mL, 1.5 mL
Servings per container
120
UPC/BARCODE
023363622078
IngredientAmount% DV
Proprietary Blend0 NP--
Nettle0 NP--
Mullein0 NP--
Eyebright0 NP--

Other ingredients: Glycerin, Water, Filtered

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Sinus Support

Gluten free Non GMO Soy free

US Grown

FDA Statement of Identity

Dietary Supplement

Formula

Kids Herbal Glycerite

100% Kosher.

Suggested/Recommended/Usage/Directions

Suggested Use: For children over 1 year of age. Use 3 times a day mixed in water, according to body weight. Under 25 lbs 10 drops; 26-50 lbs 15 drops; 51-75 lbs 20 drops; 76-100 lbs 25 drops, over 100 lbs 30 drops.

Precautions

For children under 1 year consult with your health care advisor. Keep out of reach of children.

Consult your health care advisor about herbs with pregnancy, infants or prescription drugs.

Discontinue use if unusual symptoms occur.

Storage

Store upright.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent diseases.

General Statements

@Eclecticherb

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Alle-Relief by Eclectic Herb label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Alle-Relief label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Alle-Relief by Eclectic Herb

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0 NP per serving

Other (inactive) ingredients: Glycerin, Water, Filtered. These complete the product’s ingredient list but are not active constituents.

Interaction report

Alle-Relief by Eclectic Herb Drug Interactions

Want to check YOUR meds against Alle-Relief?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
284Drugs
164 Moderate 120 Minor

Ingredients driving the most interactions

Nettle 164
Mullein 122
Eyebright 86

Individual Drug Interactions

The ingredients in Alle-Relief interact with 284 drugs. Click any drug to see the details.

3 of the 3 ingredients in Alle-Relief interact with drugs. Each result below shows which ingredient is responsible. Nettle Mullein Eyebright

Each ingredient & the kinds of drugs it affects

For each ingredient in Alle-Relief with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Nettle4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Nettle full monograph & interactions

Mullein1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein full monograph & interactions

Eyebright1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.

Likelihood Possible Evidence D
Eyebright full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Alle-Relief, from the product label.

Eclectic Herb

See all Eclectic Herb products
Name
Eclectic Herb
Street Address
755 NE 6th St.
City
Gresham
State
Oregon
ZipCode
97030
Phone Number
503.668.4120
Web Address
www.eclecticherb.com
Pharmacist Counseling Corner

Alle-Relief by Eclectic Herb: Common Questions

Does Alle-Relief by Eclectic Herb interact with any medications?
Yes. Based on its ingredients, Alle-Relief has a known interaction with 284 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alle-Relief contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product work for hay fever and allergies?
The ingredients have been used traditionally for allergies, but we don't have reliable evidence that they actually work for hay fever or allergic rhinitis. Nettle is possibly effective for diabetes, but that's the strongest rating we have for any condition this product targets.
Can I take this while pregnant?
No — nettle, mullein, and eyebright all lack sufficient safety data for pregnancy. Nettle has additional traditional concerns about effects on the uterus. Talk with your doctor before using this product if you're pregnant or thinking about it.
Is it safe to breastfeed while taking Alle-Relief?
The safety data for all three ingredients during breastfeeding hasn't been established, so it's best to avoid it. Talk with your doctor or pharmacist about whether it's right for you.
What are the side effects of nettle?
When taken by mouth, nettle most commonly causes constipation or diarrhea. In rare cases, liver problems have been reported in people taking herbal products containing nettle, though other ingredients were also involved. If you touch raw plant parts directly, you may get itching, rash, or stinging.
Why do I need to check my blood thinner medication with this product?
Nettle contains a lot of vitamin K, which — in large amounts — can work against warfarin and other blood thinners. That's a Moderate concern that could affect how well your medication works, so it's important to verify your specific drug before starting.
Is this product a filler-free formula?
No — besides the three active ingredients, it contains glycerin and filtered water. These are inactive ingredients that help deliver the formula as a liquid.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alle-Relief label
Go deeper

The Full Monographs Behind Alle-Relief’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph → Herb & supplement monograph

Eyebright

Interacts with 86 drugs

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to c...

Read the full Eyebright monograph →
Sources

Sources & How We Checked

Alle-Relief's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
  10. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
  11. Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
  12. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
  13. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
  14. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
  15. Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
  16. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
  17. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
  18. Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
  19. Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
  20. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
  21. Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
  22. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
  23. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed

See these in context on the Stinging Nettle monograph →

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Eyebright 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

See these in context on the Eyebright monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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