Aloe Vera Gel Extract Ingredients & Drug Interactions
by DC
What is this page for?
First and foremost: checking Aloe Vera Gel Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Vera Gel Extract is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe vera Gel Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Vera Gel Extract by DC
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Vera Gel Extract by DC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Aloe Vera Gel Extract by DC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: aloe vera gel concentrate. The inactive ingredients are soybean oil, gelatin, glycerin, and white beeswax.
Does it work?
Moderate evidence
Aloe vera gel shows possibly effective evidence for acne, psoriasis, burns, constipation, obesity, and diabetes. The data we hold doesn't establish how strong that evidence is for any of these uses, so talk with your pharmacist or doctor about whether it's a fit for what you're treating.
How safe is it?
Well-documented data
Topical aloe gel is generally well tolerated, but oral aloe—including this supplement—carries more risk, especially at high doses or with long-term use. Common side effects when taken by mouth include abdominal pain, cramps, and diarrhea.
Rare serious effects from long-term use include severe potassium loss (hypokalemia), muscle weakness, heart rhythm problems, and discoloration of the intestinal lining (pseudomelanosis coli), which usually reverses if you stop taking it. The safety data advises against taking aloe by mouth during pregnancy because the latex may stimulate the uterus and cause strong laxative effects.
The same caution applies to breastfeeding because of limited safety data and laxative effects. If you're pregnant, planning pregnancy, or breastfeeding, talk with your pharmacist or doctor before starting.
Meds to double-check
Major interaction found
Before taking this, check your exact medications. Major concern: digoxin and other heart medications (cardiac glycosides).
Moderate concerns include blood thinners (anticoagulants and antiplatelet drugs), diabetes medications, diuretics (water pills), warfarin (Coumadin), and stimulant laxatives. If you take any of these, run them through the checker on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
Aloe vera gel is possibly effective for several conditions, including burns, constipation, and acne. But it carries real risks—especially Major interactions with heart medications like digoxin and Moderate risks with blood thinners, diabetes drugs, and diuretics.
If you take any prescription medications, check them against this product before you start. Pregnant and breastfeeding people should talk with their pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Vera Gel Extract, straight from the product label.
| Brand | DC |
|---|---|
| Net contents | 180 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2022 |
| DSLD ID | 266232 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Vera Gel Extract by DC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Aloe vera Gel Concentrate | 75 mg | -- |
Other ingredients: Soybean Oil, Gelatin, Glycerin, White Beeswax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 3 softgels 1-3 times daily, on an empty stomach.
Precautions
Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing do not take this product.
Contains soy ingredients
Formulation
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Contains no artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no wheat, no yeast, no fish and is sodium free.
New higher dose
Gluten free
Made in USA
Storage
Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
Seals/Symbols
Quali Pure
Formula
Equivalent to 15,000 mg of pure aloe vera
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Vera Gel Extract by DC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Vera Gel Extract by DC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.
Aloe vera Gel Concentrate
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Aloe vera Gel Concentrate monograph & interactionsOther (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, White Beeswax. These complete the product’s ingredient list but are not active constituents.
Aloe Vera Gel Extract by DC Drug Interactions
HelloPharmacist Interaction Report
Aloe Vera Gel Extract by DC contains one active ingredient—aloe vera gel concentrate—that interacts with several medication types.
The most serious concern is digoxin (Lanoxin), a heart medication. Overuse of aloe can deplete potassium, and when combined with digoxin, this raises the risk of toxicity and serious adverse effects.
Read the full breakdown — every affected drug type, severity by severity
Aloe also carries Moderate interactions with blood thinners (anticoagulants) and antiplatelet drugs—the gel can slow blood clotting and increase bleeding risk. If you take diabetes medications, aloe might lower blood sugar further, raising the risk of low blood sugar (hypoglycemia); monitor your levels closely.
Similarly, diuretics (water pills) combined with aloe may worsen potassium loss, and using aloe with stimulant laxatives can compound fluid and electrolyte depletion. Warfarin (Coumadin) users should be aware that aloe's laxative effects can cause diarrhea, which increases warfarin's blood-thinning effect and bleeding risk.
Aloe also has a Minor interaction with certain drugs broken down by the enzyme CYP1A2—the herb may reduce their effectiveness.
Altogether, these interactions span 461 individual medications. Use the medication checker on this page to look up any prescriptions you take before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Vera Gel Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Vera Gel Extract interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Vera Gel Extract interact with drugs. Each result below shows which ingredient is responsible. Aloe vera Gel Concentrate
Castor Oil (otc Drug)Purge
How Castor Oil (otc Drug) interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Gel Concentrate + Castor Oil (otc Drug) interactionChlorothiazideDiuril
How Chlorothiazide interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Chlorothiazide, Reserpine interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel Concentrate + Chlorpropamide interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Chlorthalidone, Clonidine interactionCilostazolPletal
How Cilostazol interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Cilostazol interactionClopidogrelPlavix
How Clopidogrel interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Gel Concentrate + Clopidogrel interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Cyclothiazide interactionDalteparinFragmin
How Dalteparin interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Dalteparin interactionDanaparoidOrgaran
How Danaparoid interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Danaparoid interactionDanthron , DocusateCo-Danthrusate (UK)
How Danthron , Docusate interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Gel Concentrate + Danthron , Docusate interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel Concentrate + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel Concentrate + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel Concentrate + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel Concentrate + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel Concentrate + Dasiglucagon Hydrochloride interactionDefibrotide SodiumDefitelio
How Defibrotide Sodium interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Defibrotide Sodium interactionDehydrocholic AcidDecholin
How Dehydrocholic Acid interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Gel Concentrate + Dehydrocholic Acid interactionDehydrocholic Acid , DocusateBilax
How Dehydrocholic Acid , Docusate interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Gel Concentrate + Dehydrocholic Acid , Docusate interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel Concentrate + Deserpidine, Methyclothiazide interactionDiclofenacZorvolex
How Diclofenac interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Diclofenac interactionDiclofenac PotassiumCambia, Cataflam, Cataflam IR, Voltaren Rapide, Voltarol Rapid
How Diclofenac Potassium interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Diclofenac Potassium interactionDiclofenac SodiumAcoflam, Acoflam 75 SR, Acoflam Retard, Defenac, Defenac Retard, Defenac SR +40 more
How Diclofenac Sodium interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Diclofenac Sodium interactionDiclofenac Sodium, MisoprostolArthrotec 50, Arthrotec 75
How Diclofenac Sodium, Misoprostol interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Diclofenac Sodium, Misoprostol interactionDiclofenac EpolamineFlector, Licart
How Diclofenac Epolamine interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Diclofenac Epolamine interactionDicumarolDicumarol
How Dicumarol interacts with Aloe Vera Gel Extract — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel Concentrate + Dicumarol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Vera Gel Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Aloe vera Gel Concentrate
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Vera Gel Extract, from the product label.
DC
See all DC products- Name
- Dee Cee Laboratories, Inc.
- Street Address
- 304 Dee Cee Ct.
- City
- White House
- State
- TN
- ZipCode
- 37188
Aloe Vera Gel Extract by DC: Common Questions
Does Aloe Vera Gel Extract by DC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is aloe vera gel concentrate, and what's it supposed to do?
Can I take this if I'm pregnant or breastfeeding?
What are the most common side effects?
Is this safe with my heart medication?
Can I take this with blood thinners?
What are the inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Vera Gel Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Vera Gel Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Vera Gel Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
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