Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Androxx 75 mg Ingredients & Drug Interactions

by Vaxxen Labs

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Androxx 75 mg is a dietary supplement by Vaxxen Labs with 3 active ingredients. Its ingredients are commonly taken for muscle building, increasing strength, athletic performance.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 1 Androstene-3b-Ol, 17-One. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Androxx 75 mg by Vaxxen Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “1-DHEA Blend” is a proprietary blend — the label gives one combined amount (75 mg) without saying how much of each component you get.

Androxx contains 3 active ingredients, all forms of 1-androsterone — a prohormone that your body converts to 1-testosterone and other androgens. The product also contains several inactive ingredients (microcrystalline cellulose, phosphatidylcholine, hydroxypropyl-beta-cyclodextrin, phytosterol, stearic acid, magnesium stearate, starch, titanium dioxide, silica, and FD&C Red #40) that help make the tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see 1-androsterone's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: lean muscle and strength support.
  • We looked for evidence on: Athletic performance, muscle mass, body composition, strength gains.
  • The closest evidence on file: 1-androsterone is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

There isn't enough reliable evidence to rate whether 1-androsterone actually boosts athletic performance. The data we hold shows insufficient evidence — so we can't tell you whether it'll work for that purpose.

The evidence, ingredient by ingredient 1-androsterone

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

1-Androsterone is a hormonal compound with real health risks and limited safety testing. The most common side effects reported are changes in cholesterol (LDL cholesterol increased by around 29 mg/dL and HDL cholesterol decreased by around 19 mg/dL over 4 weeks), liver enzyme elevation, and kidney issues — including reduced kidney function (GFR dropped below normal range despite serum creatinine staying in the normal range).

Safety data is sparse, so a full picture of how often these happen or how serious they can get isn't available. Don't use this product if you're pregnant — hormone-altering prohormones carry real risks to a developing baby.

Avoid it while breastfeeding too, because the hormonal effects on your baby aren't known.

Side effects, ingredient by ingredient 1-androsterone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — 1-androsterone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Androxx, check with your doctor or pharmacist if you use any testosterone medications or products. This is the only medication type with documented interaction concerns, but because 1-androsterone is a hormone-altering compound, your doctor may want to review your whole medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Androxx is a potent hormone-altering prohormone with documented risks to your liver, kidneys, and cholesterol levels and only sparse safety data behind it. It's not for anyone pregnant or breastfeeding.

If you take testosterone or any other medication, talk with your doctor or pharmacist before starting — interactions are possible and worth weighing against the uncertain benefits.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Androxx 75 mg, straight from the product label.

Brand Vaxxen Labs
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 175560
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Androxx 75 mg by Vaxxen Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
IngredientAmount% DV
1-DHEA Blend75 mg--
1 Androstene-3b-Ol, 17-One0 NP--
1 Androstene-3b-Ol,17-One Undecanoate0 NP--
1 Androstene-3b-Ol,17-One Caprylate0 NP--

Other ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl-Beta-Cyclodextrin, Phytosterol, Stearic Acid, Magnesium Stearate, Starch, Titanium Dioxide, Silica, FD&C Red #40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Lean muscle agent Liposomal delivery system

FDA Statement of Identity

Dietary Supplement

See for yourself

Androxx 75 mg by Vaxxen Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Androxx 75 mg by Vaxxen Labs

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl-Beta-Cyclodextrin, Phytosterol, Stearic Acid, Magnesium Stearate, Starch, Titanium Dioxide, Silica, FD&C Red #40. These complete the product’s ingredient list but are not active constituents.

Interaction report

Androxx 75 mg by Vaxxen Labs Drug Interactions

Want to check YOUR meds against Androxx 75 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
8Drugs
8 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Androxx 75 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

1 Androstene-3b-Ol, 17-One1 drug type · 8 drugs

Testosterone

Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Androxx 75 mg, from the product label.

Vaxxen Labs

See all Vaxxen Labs products
Name
Vaxxen Labs
Pharmacist Counseling Corner

Androxx 75 mg by Vaxxen Labs: Common Questions

Does Androxx 75 mg by Vaxxen Labs interact with any medications?
Yes. Based on its ingredients, Androxx 75 mg has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Androxx 75 mg contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me with athletic performance?
The evidence we hold doesn't show that 1-androsterone reliably improves athletic performance — there just isn't enough data to say either way. If you're thinking about it for that reason, talk it over with your doctor first.
What are the most common side effects?
The main ones reported are changes in cholesterol levels (LDL up, HDL down), liver enzyme elevation, and kidney issues including reduced kidney function. Safety data is limited, so the full picture of how often these happen isn't clear.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against it. Hormone-altering prohormones shouldn't be used during pregnancy because of real risks to the baby, and you should avoid it while breastfeeding because the hormonal effects on your baby aren't known.
What is 1-androsterone?
It's a prohormone — a compound your body converts to testosterone and related androgens when you take it. It's not a hormone itself, but it acts like one once it's processed.
Why should I check my medications before starting?
Because 1-androsterone can theoretically cause problems if you're also taking testosterone — mood changes, heart issues, kidney damage, or liver damage. Your doctor needs to know about all your medications to make sure it's safe to add this.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Androxx 75 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Androxx 75 mg label
Sources

Sources & How We Checked

Androxx 75 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

1-androsterone 2 references
  1. Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
  2. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

See these in context on the 1-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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