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Dietary supplement

Artemisinin 200 mg Ingredients & Drug Interactions

by Double Wood Supplements

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Artemisinin 200 mg is a dietary supplement by Double Wood Supplements with 1 active ingredient. Its ingredients are commonly taken for malaria (traditional), fever, inflammation.Based on those ingredients, 889 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Artemisinin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Artemisinin 200 mg by Double Wood Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: artemisinin 200 mg per capsule, derived from Sweet Annie. It also contains two inactive ingredients — hypromellose and rice flour — which serve as capsule material and filler to help deliver the dose.

Artemisinin is the compound historically used in traditional medicine and studied for immune and inflammatory support. The 200 mg dose is a single, straightforward formulation with no added herbs or cofactors.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: immune system health and healthy aging.
  • We looked for evidence on: Malaria, fever, inflammation, antimicrobial support.
  • The strongest evidence on file: Sweet Annie is rated "Possibly Effective" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Sweet Annie is rated "Insufficient Reliable Evidence To Rate" for Malaria.

For allergic rhinitis (hay fever), artemisinin carries a Possibly Effective rating — there's some evidence, but it's not conclusive. For nonalcoholic fatty liver disease (NAFLD), malaria, and osteoarthritis, the evidence isn't established well enough in the data we hold to rate it reliably.

If you're considering artemisinin for any condition, talk with your doctor or pharmacist about what the current research actually supports for your specific situation.

The evidence, ingredient by ingredient Sweet Annie

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, artemisinin is generally well tolerated. The most common side effects are nausea and vomiting in trial participants.

Rarely, liver damage (hepatotoxicity) has been reported — one documented case involved liver inflammation after taking 200 mg three times daily for 10 days, though it's unclear whether artemisinin caused it or another factor was responsible. A mild allergic reaction (rash and cough) has been reported once.

Because of the liver concern and the fact that dosing and quality vary widely across supplements, don't use artemisinin as a replacement for proven medical treatments without your doctor's input. Artemisinin should be avoided during pregnancy because of possible harm to a developing baby.

It should also be avoided while breastfeeding due to insufficient safety information. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your healthcare provider before considering this product.

Side effects, ingredient by ingredient Sweet Annie

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sweet Annie.
  • The most serious interaction on file is rated Moderate.
  • For scale: 890 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking artemisinin, check with your pharmacist if you take any hepatotoxic drugs (medications that can harm the liver), or any drugs metabolized by the liver enzymes CYP3A4 or CYP2B6 — the interactions are Moderate for all three categories and may change how well your medications work or increase liver stress.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Artemisinin may help with hay fever symptoms, but it interacts with a very large number of medications through liver metabolism and carries a moderate risk with drugs that can damage the liver itself. If you take any prescription or over-the-counter medications, check them against this product using the tool on this page before starting.

And because it's not a proven treatment for serious conditions like malaria or fatty liver disease, it shouldn't replace standard care.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Artemisinin 200 mg, straight from the product label.

Brand Double Wood Supplements
Barcode (UPC) 859793007792
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241711
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Artemisinin 200 mg by Double Wood Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
859793007792
IngredientAmount% DV
Artemisinin200 mg--

Other ingredients: Hypromellose, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Artemisinin is a compound extracted from sweet wormwood (artemisia annua). Artemisinin is often taken as a supplement for immune system health.

200mg per serving

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1-2 capsules per day with food. Do not exceed 3 capsules in one day.

Storage

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature.

Formulation

Proudly made in USA

Made with Non-GMO ingredients Gluten free

Supports immune system health Supports healthy aging and cell repair

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Consult your physician before use.

Do not use Artemisinin if you are pregnant, nursing or are under 18 years of age.

Do not use Artemisinin if you are pregnant, nursing or are under 18 years of age.

Discontinue use and consult your doctor immediately if any adverse reactions occur.

Do not Artemisinin and operate heavy machinery until you know how it affects you.

Keep out of reach of children.

Do not exceed 3 capsules per day.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Artemisinin 200 mg by Double Wood Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Artemisinin 200 mg by Double Wood Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Artemisinin

Interacts with
889 drugs
200 mg per serving Form: Sweet Wormwood

Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studie...

Artemisinin monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Artemisinin 200 mg by Double Wood Supplements Drug Interactions

Want to check YOUR meds against Artemisinin 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
889Drugs
889 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Artemisinin 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Artemisinin3 drug types · 889 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP2B6, possibly increasing CYP2B6 activity by 1.6-fold. However, Sweet Annie extract seems to inhibit the activity of CYP2B6 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP2B6 substrates.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP3A4, possibly increasing CYP3A4 activity by 1.9-fold. However, Sweet Annie extract seems to inhibit the activity of CYP3A4 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP3A4 substrates.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use might have additive adverse hepatotoxic effects.
There is some concern that Sweet Annie can adversely affect the liver.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Artemisinin 200 mg, from the product label.

Double Wood Supplements

See all Double Wood Supplements products
Name
Double Wood LLC
Street Address
3510 Scotts Ln Ste 219
City
Philadelphia
State
PA
ZipCode
19129-1573
Web Address
www.doublewoodsupplements.com
Pharmacist Counseling Corner

Artemisinin 200 mg by Double Wood Supplements: Common Questions

Does Artemisinin 200 mg by Double Wood Supplements interact with any medications?
Yes. Based on its ingredients, Artemisinin 200 mg has a known interaction with 889 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Artemisinin 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take artemisinin if I'm pregnant or breastfeeding?
No — the safety data advises against it. Artemisinin should be avoided during pregnancy because of possible harm to your developing baby, and avoided while breastfeeding because there isn't enough information to know it's safe. If you're in either situation, talk with your doctor or pharmacist before considering this product.
What are the most common side effects?
Nausea and vomiting are the most common side effects reported when taking artemisinin orally. These are generally mild. Rarely, liver damage has been reported, though it's not always clear that artemisinin caused it.
Does artemisinin actually work for hay fever?
Artemisinin carries a Possibly Effective rating for hay fever — meaning there is some evidence, but it's not definitive. For other uses like malaria, fatty liver disease, or osteoarthritis, the evidence we hold isn't strong enough to rate it reliably.
How long can I take this supplement?
Artemisinin is generally used short-term, and quality and dose vary widely across brands. Because there's also a documented case of liver inflammation from short-term use, don't use it as a long-term replacement for proven treatments without talking to your doctor or pharmacist first.
What is artemisinin and where does it come from?
Artemisinin is the active compound derived from Sweet Annie, a plant used historically in traditional medicine. This product contains 200 mg of artemisinin per capsule with no added herbs or cofactors.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Artemisinin 200 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Artemisinin 200 mg label
Sources

Sources & How We Checked

Artemisinin 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sweet Annie 11 references
  1. Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects. J Ethnopharmacol 2000;73:487-93. PubMed
  2. Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop Med Hyg 2004;70:128-32. DOI
  3. Centers for Disease Control and Prevention (CDC). Hepatitis temporally associated with an herbal supplement containing artemisinin-Washington, 2008. MMWR Morb Mortal Wkly Rep 2009;58:854-8.
  4. Xing J, Kirby BJ, Whittington D, et al. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug Metabl Dispos 2012;40(9):1757-64. PubMed
  5. Savage RL, Hill GR, Barnes J, Kenyon SH, Tatley MV. Suspected hepatotoxicity with a supercritical carbon dioxide extract of Artemisia annua in grapeseed oil used in New Zealand. Front Pharmacol. 2019;10:1448. PubMed
  6. Ruperti-Repilado FJ, Haefliger S, Rehm S, et al. Danger of herbal tea: a case of acute cholestatic hepatitis due to Artemisia annua tea. Front Med (Lausanne). 2019;6:221. PubMed
  7. Yang J, Shen Z, Liu L, et al. Clinical efficacy and safety of Artesimia annua-Sublingual immunotherapy in seasonal allergic rhinitis patients based on different intervention time. Int Arch Allergy Immunol 2022;183(8):852-859.
  8. Kane NF, Kiani BH, Desrosiers MR, Towler MJ, Weathers PJ. Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro. J Ethnopharmacol 2022. DOI
  9. Feng Y, Cao Y, Liu Y, et al. Clinical efficacy and safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia-induced rhinoconjunctivitis. Am J Otolaryngol 2023;44(5):103942. PubMed
  10. Yang J, Wang W, Shen Z, et al. Efficacy and safety of Artemisia annua sublingual immunotherapy in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. Eur Arch Otorhinolaryngol. 2023;280(11):4939-4947. PubMed
  11. Shen Z, Zhang P, Kang W, et al. Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals. Am J Otolaryngol 2023;44(6):104002. PubMed

See these in context on the Sweet Annie monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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