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Dietary supplement

Artemisinin Ingredients & Drug Interactions

by NutriCology

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Artemisinin is a dietary supplement by NutriCology with 1 active ingredient. Its ingredients are commonly taken for malaria (traditional), fever, inflammation.Based on those ingredients, 889 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Artemisinin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Artemisinin by NutriCology

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: artemisinin, a compound extracted from Sweet Annie (a traditional plant). Artemisinin has been studied mainly for hay fever and malaria, though the evidence for those uses is still developing.

The capsule itself is made from inactive ingredients — a plant-based cellulose capsule, microcrystalline cellulose as a filler, and magnesium stearate as a lubricant.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Sweet Annie's overall clinical evidence instead.

Moderate

Some clinical evidence supports Sweet Annie for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Allergic rhinitis (hay fever) — rated "Possibly Effective" (Natural Medicines).

The data we hold shows artemisinin may be possibly effective for allergic rhinitis (hay fever). For nonalcoholic fatty liver disease, malaria, and osteoarthritis, the evidence isn't established — there isn't enough reliable data to say whether it works for those conditions.

If you're considering this for hay fever, talk with your pharmacist or doctor about whether the evidence fits your situation.

The evidence, ingredient by ingredient Sweet Annie

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Artemisinin is generally well tolerated when taken by mouth. The most common side effects reported are nausea and vomiting.

Rare but serious concerns include liver damage (hepatotoxicity); one case described a patient who developed hepatitis after 10 days of use, with symptoms that resolved after stopping. A mild allergic reaction (rash and cough) has also been reported, as well as tongue numbness and throat itching in people who are allergic to Sweet Annie.

The safety data advises against use during pregnancy because of possible harm to the developing baby. There isn't enough information to know whether it's safe while breastfeeding — talk with your doctor or pharmacist for personalized advice.

This product is generally used short-term, and it should not replace proven medical treatments.

Side effects, ingredient by ingredient Sweet Annie

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sweet Annie.
  • The most serious interaction on file is rated Moderate.
  • For scale: 890 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take artemisinin, check your medications against these drug types: drugs metabolized by CYP3A4 (a major liver enzyme — includes cholesterol drugs, some blood pressure medications, and immunosuppressants), drugs metabolized by CYP2B6, and any medications known to damage the liver. Use the search tool on this page to check your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Artemisinin may be worth considering if you have hay fever and want to explore the evidence — but it's not a first-line option yet. If you take any prescription medications, especially cholesterol drugs, blood pressure medications, or immunosuppressants, you need to check with your pharmacist before starting.

Avoid it during pregnancy, and talk to your doctor if you're breastfeeding or have any liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Artemisinin, straight from the product label.

Brand NutriCology
Barcode (UPC) 713947556805
Net contents 300 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 258467
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Artemisinin by NutriCology, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
150
UPC/BARCODE
713947556805
IngredientAmount% DV
Artemisinin200 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Nu-Mag

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pure artemisinin or Qinghaosu, the active constituent of the herb Artemisia annua (sweet wormwood).

Pure Qinghaosu from Artemisia annua

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 1 or 2 capsules one or two times daily before meals, or as directed by a healthcare practitioner. Artemisinin is best taken as part of a program that includes appropriate liver support nutrients. Sensitive individuals may want to take with food.

Precautions

Caution: Not indicated for pregnant or nursing women.

This product should only be used under the guidance of a qualified healthcare practitioner with ongoing monitoring of liver enzymes and hemoglobin during its use. In rare cases may cause idiosyncratic liver dysfunction. Combining with antioxidants or iron may theoretically decrease effectiveness.

General Statements

NutriCology Innovative Nutrition

Formulation

Hypoallergenic

FDA Statement of Identity

Dietary Supplement

Storage

Keep in a cool, dry place, tightly capped.

Brand IP Statement(s)

Nu-MAG is a trademark of RIBUS, Inc.

See for yourself

Artemisinin by NutriCology label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Artemisinin by NutriCology

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container150 Amounts shown are per serving.

Artemisinin

Interacts with
889 drugs
200 mg per serving

Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studie...

Artemisinin monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Nu-Mag. These complete the product’s ingredient list but are not active constituents.

Interaction report

Artemisinin by NutriCology Drug Interactions

Want to check YOUR meds against Artemisinin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
889Drugs
889 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Artemisinin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Artemisinin3 drug types · 889 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP2B6, possibly increasing CYP2B6 activity by 1.6-fold. However, Sweet Annie extract seems to inhibit the activity of CYP2B6 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP2B6 substrates.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP3A4, possibly increasing CYP3A4 activity by 1.9-fold. However, Sweet Annie extract seems to inhibit the activity of CYP3A4 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP3A4 substrates.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use might have additive adverse hepatotoxic effects.
There is some concern that Sweet Annie can adversely affect the liver.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Artemisinin, from the product label.

NutriCology

See all NutriCology products
Name
NutriCology
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800.545.9960
Web Address
www.nutricology.com
Pharmacist Counseling Corner

Artemisinin by NutriCology: Common Questions

Does Artemisinin by NutriCology interact with any medications?
Yes. Based on its ingredients, Artemisinin has a known interaction with 889 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Artemisinin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is artemisinin and where does it come from?
Artemisinin is an active compound extracted from Sweet Annie, a plant used in traditional medicine. It's been studied for conditions like hay fever and malaria, though the evidence for those uses is still developing.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against artemisinin during pregnancy because of possible harm to the developing baby. If you're breastfeeding, there isn't enough information to know whether it's safe, so talk with your doctor or pharmacist for personalized advice.
What are the most common side effects?
Nausea and vomiting are the most common side effects reported when taken by mouth. A mild allergic reaction (rash and cough) has also been reported in rare cases.
Is artemisinin effective for hay fever?
The data shows artemisinin may be possibly effective for allergic rhinitis (hay fever), but the evidence is still limited. Ask your pharmacist whether it fits your situation and how it compares to other options.
Can artemisinin damage my liver?
Liver damage is rare but serious. One case described a patient who developed hepatitis after 10 days of use at high doses — symptoms resolved after stopping. Because there's some concern artemisinin can affect the liver, don't use it if you take other drugs that damage the liver, and don't use it if you have liver disease.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Artemisinin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Artemisinin label
Sources

Sources & How We Checked

Artemisinin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sweet Annie 11 references
  1. Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects. J Ethnopharmacol 2000;73:487-93. PubMed
  2. Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop Med Hyg 2004;70:128-32. DOI
  3. Centers for Disease Control and Prevention (CDC). Hepatitis temporally associated with an herbal supplement containing artemisinin-Washington, 2008. MMWR Morb Mortal Wkly Rep 2009;58:854-8.
  4. Xing J, Kirby BJ, Whittington D, et al. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug Metabl Dispos 2012;40(9):1757-64. PubMed
  5. Savage RL, Hill GR, Barnes J, Kenyon SH, Tatley MV. Suspected hepatotoxicity with a supercritical carbon dioxide extract of Artemisia annua in grapeseed oil used in New Zealand. Front Pharmacol. 2019;10:1448. PubMed
  6. Ruperti-Repilado FJ, Haefliger S, Rehm S, et al. Danger of herbal tea: a case of acute cholestatic hepatitis due to Artemisia annua tea. Front Med (Lausanne). 2019;6:221. PubMed
  7. Yang J, Shen Z, Liu L, et al. Clinical efficacy and safety of Artesimia annua-Sublingual immunotherapy in seasonal allergic rhinitis patients based on different intervention time. Int Arch Allergy Immunol 2022;183(8):852-859.
  8. Kane NF, Kiani BH, Desrosiers MR, Towler MJ, Weathers PJ. Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro. J Ethnopharmacol 2022. DOI
  9. Feng Y, Cao Y, Liu Y, et al. Clinical efficacy and safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia-induced rhinoconjunctivitis. Am J Otolaryngol 2023;44(5):103942. PubMed
  10. Yang J, Wang W, Shen Z, et al. Efficacy and safety of Artemisia annua sublingual immunotherapy in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. Eur Arch Otorhinolaryngol. 2023;280(11):4939-4947. PubMed
  11. Shen Z, Zhang P, Kang W, et al. Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals. Am J Otolaryngol 2023;44(6):104002. PubMed

See these in context on the Sweet Annie monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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