Artemisinin Powder Ingredients & Drug Interactions
by Herbadiet
What is this page for?
First and foremost: checking Artemisinin Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Artemisinin Powder is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for malaria (traditional), fever, inflammation.Based on those ingredients, 889 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Artemisia annua Leaf Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Artemisinin Powder by Herbadiet
Ask about any prescription or over-the-counter medication and we check it for interactions with Artemisinin Powder by Herbadiet — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Artemisinin Powder by Herbadiet
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This is a single-ingredient product: Artemisia annua Leaf Extract in powder form, commonly known as Sweet Annie. The extract is the active ingredient — there are no inactive fillers or other added materials.
Does it work?
Couldn't assess
The evidence for Sweet Annie varies by use. For allergic rhinitis (hay fever), it is rated as possibly effective — there is some data supporting benefit, but it's not conclusive.
For nonalcoholic fatty liver disease (NAFLD), osteoarthritis, and malaria, the evidence is insufficient to rate; we simply don't have reliable data yet to know whether it works for those purposes.
How safe is it?
Well-documented data
Taken by mouth, Sweet Annie is generally well tolerated, though nausea and vomiting are the most common side effects reported. A rare serious concern is liver damage (hepatotoxicity); one case involved a patient who developed hepatitis after taking artemisinin 200 mg three times daily for 10 days, with symptoms resolving within 2 weeks of stopping.
One mild allergic reaction (rash and cough) has been reported, and some people have reported numbness of the tongue or throat itching when small doses are placed under the tongue. The product is labeled for short-term use, and quality and dose vary widely across products — it should never replace proven medical treatments.
During pregnancy, the safety data advises against use because of possible harm to the developing baby. There is not enough safety information to use this while breastfeeding; talk with your doctor or pharmacist about whether it is right for you.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist about any medications you take that are metabolized by CYP3A4 or CYP2B6 enzymes — a broad group that includes many common drugs. Also flag any medications that stress the liver (hepatotoxic drugs).
The interaction severity is Moderate across all three categories, meaning your medication levels could shift and their effects could change.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Herbadiet's Artemisinin Powder may be considered if you're exploring options for hay fever and want to check for potential interactions, but it comes with documented risks to the liver and significant effects on how your body processes medications. The evidence for other uses isn't established yet.
If you take any prescription or over-the-counter medications, check them against this product with your own doctor or pharmacist before you start, and avoid it entirely if you're pregnant or breastfeeding without medical guidance.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Artemisinin Powder, straight from the product label.
| Brand | Herbadiet |
|---|---|
| Net contents | 0 Not Present |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 293720 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Artemisinin Powder by Herbadiet, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Artemisia annua Leaf Extract, Powder | 100 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Antifiungal & antibacterial
Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast
Being a natural produce, there can be minor color variations because of geographical & seasonal variation of the raw material. Herbal extracts can be hygroscopic & may agglomerate at times. This, in no way, affect the efficacy of the product.
Vegan
Ethically sourced Scientifically tested Premium grade ingredients
Formula
Standardized extract powder derived from Artemisia Annua leaves
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take up to 200 mg, or as directed by your physician
Precautions
Keep out of reach of children.
Pregnant or lactating women should consult your physician before use.
Storage
Store in a dry, cool & dark.
FDA Disclaimer Statement
Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
FSSAI (Food Safety and Standards Authority of India) Lic. No.: 20817018000147
General Statements
Batch No.: ARK/P/174
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Artemisinin Powder by Herbadiet label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Artemisinin Powder by Herbadiet
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size100 mg Dosage formPowder Amounts shown are per serving.
Artemisia annua Leaf Extract, Powder
Interacts with889 drugs
Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studie...
Artemisia annua Leaf Extract, Powder monograph & interactionsArtemisinin Powder by Herbadiet Drug Interactions
HelloPharmacist Interaction Report
Herbadiet's Artemisinin Powder contains one active ingredient — Artemisia annua Leaf Extract (Sweet Annie) — that does interact with medications.
The most serious documented concern is with drugs that stress the liver (hepatotoxic drugs), where concomitant use could theoretically add to liver damage; this is a Moderate-severity risk.
Read the full breakdown — every affected drug type, severity by severity
Sweet Annie also affects how your body metabolizes two major groups of drugs. It may change the blood levels and effects of medications broken down by CYP3A4 (a major liver enzyme system), and separately, it may alter medications processed by CYP2B6.
Both of these are Moderate-severity interactions. The science here is mixed — in test tubes, one component of Sweet Annie (artemisinin) appears to speed up these enzymes, but the whole extract seems to slow them down, so the real-world effect is uncertain and may vary.
Because of these enzyme effects, blood levels of your medications could go up or down, changing how well they work. Altogether, these interactions span 890 individual medications.
You'll want to check your exact medications with the tool on this page before starting, and discuss the results with your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Artemisinin Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Artemisinin Powder interact with 889 drugs. Click any drug to see the details.
1 of the 1 ingredient in Artemisinin Powder interact with drugs. Each result below shows which ingredient is responsible. Artemisia annua Leaf Extract, Powder
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Abacavir, Lamivudine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Artemisinin Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Leaf Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Leaf Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Artemisinin Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Artemisia annua Leaf Extract, Powder
Cytochrome P450 2B6 (Cyp2B6) Substrates
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP2B6, possibly increasing CYP2B6 activity by 1.6-fold. However, Sweet Annie extract seems to inhibit the activity of CYP2B6 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP2B6 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP3A4, possibly increasing CYP3A4 activity by 1.9-fold. However, Sweet Annie extract seems to inhibit the activity of CYP3A4 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP3A4 substrates.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
There is some concern that Sweet Annie can adversely affect the liver.
Brand information
Manufacturer and brand details for Artemisinin Powder, from the product label.
Herbadiet
See all Herbadiet products- Name
- Arkure Health Care
- Street Address
- 11, Sector - 14
- City
- Rohtak
- State
- Haryana
- ZipCode
- 124001
- Web Address
- www.herbadiet.in
Artemisinin Powder by Herbadiet: Common Questions
Does Artemisinin Powder by Herbadiet interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this work for hay fever?
What are the most common side effects?
Can I take this while pregnant or breastfeeding?
Does it affect how my liver works?
Can I take this long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Artemisinin Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Artemisinin Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Artemisinin Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sweet Annie 11 references
- Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects. J Ethnopharmacol 2000;73:487-93. PubMed
- Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop Med Hyg 2004;70:128-32. DOI
- Centers for Disease Control and Prevention (CDC). Hepatitis temporally associated with an herbal supplement containing artemisinin-Washington, 2008. MMWR Morb Mortal Wkly Rep 2009;58:854-8.
- Xing J, Kirby BJ, Whittington D, et al. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug Metabl Dispos 2012;40(9):1757-64. PubMed
- Savage RL, Hill GR, Barnes J, Kenyon SH, Tatley MV. Suspected hepatotoxicity with a supercritical carbon dioxide extract of Artemisia annua in grapeseed oil used in New Zealand. Front Pharmacol. 2019;10:1448. PubMed
- Ruperti-Repilado FJ, Haefliger S, Rehm S, et al. Danger of herbal tea: a case of acute cholestatic hepatitis due to Artemisia annua tea. Front Med (Lausanne). 2019;6:221. PubMed
- Yang J, Shen Z, Liu L, et al. Clinical efficacy and safety of Artesimia annua-Sublingual immunotherapy in seasonal allergic rhinitis patients based on different intervention time. Int Arch Allergy Immunol 2022;183(8):852-859.
- Kane NF, Kiani BH, Desrosiers MR, Towler MJ, Weathers PJ. Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro. J Ethnopharmacol 2022. DOI
- Feng Y, Cao Y, Liu Y, et al. Clinical efficacy and safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia-induced rhinoconjunctivitis. Am J Otolaryngol 2023;44(5):103942. PubMed
- Yang J, Wang W, Shen Z, et al. Efficacy and safety of Artemisia annua sublingual immunotherapy in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. Eur Arch Otorhinolaryngol. 2023;280(11):4939-4947. PubMed
- Shen Z, Zhang P, Kang W, et al. Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals. Am J Otolaryngol 2023;44(6):104002. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC