Artemisia Annua Extract Powder Ingredients & Drug Interactions
by Herbadiet
What is this page for?
First and foremost: checking Artemisia Annua Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Artemisia Annua Extract Powder is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for malaria (traditional), fever, inflammation.Based on those ingredients, 889 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Artemisia annua Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Artemisia Annua Extract Powder by Herbadiet
Ask about any prescription or over-the-counter medication and we check it for interactions with Artemisia Annua Extract Powder by Herbadiet — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Artemisia Annua Extract Powder by Herbadiet
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Artemisia annua Extract in powder form, commonly known as Sweet Annie. There are no inactive fillers or other ingredients listed.
Sweet Annie has been used traditionally for fever, inflammation, and parasitic infections. Its main active compound is artemisinin, which is also used in antimalarial medications.
Does it work?
Couldn't assess
The evidence for Sweet Annie is mixed and incomplete. It's rated possibly effective for allergic rhinitis (hay fever), meaning some evidence exists but more research is needed.
For nonalcoholic fatty liver disease (NAFLD), malaria, and osteoarthritis, we don't have enough reliable evidence in our data to rate whether it works.
How safe is it?
Well-documented data
Taken by mouth, Sweet Annie is generally well tolerated, though nausea and vomiting are the most common side effects people report. Rare cases of liver damage (hepatotoxicity) have been reported—one documented case involved hepatitis that developed after 10 days of high-dose artemisinin and resolved after stopping it.
A mild allergic reaction with rash and cough has also been reported once. The safety data advises against use during pregnancy because of possible harm to the developing baby.
There isn't enough information to know whether it's safe while breastfeeding, so avoid it during that time as well. Because quality and dose vary widely between products, Sweet Annie should not replace proven treatments, and it's generally used only short-term.
Meds to double-check
Moderate interaction found
Before taking this product, double-check these medication types with your doctor or pharmacist: hepatotoxic drugs (medications that can affect the liver), and drugs broken down by the liver enzymes CYP3A4 and CYP2B6 (including many heart, brain, and cancer medications). Both carry Moderate severity risk.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you have allergic rhinitis and want to try an herbal approach, Sweet Annie has some evidence behind it—but check with your doctor or pharmacist first, especially if you take any medications. The liver interactions and the risk of liver damage mean this isn't a casual add-on, and your own healthcare provider needs to know before you start it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Artemisia Annua Extract Powder, straight from the product label.
| Brand | Herbadiet |
|---|---|
| Net contents | 0 Not Present |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 293512 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Artemisia Annua Extract Powder by Herbadiet, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Artemisia annua Extract, Powder | 500 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Antifungal & antibacterial
Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast
Being a natural produce, there can be minor color variations because of geographical & seasonal variation of the raw material. Herbal extracts can be hygroscopic & may agglomerate at times. This, in no way, affect the efficacy of the product.
Vegan
Ethically sourced Scientifically tested Premium grade ingredients
Formula
Standardized extract powder derived from Artemisia annua leaves
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take up to 1000 mg, or as directed by your physician
Precautions
Keep out of reach of children.
Pregnant or lactating women should consult your physician before use.
Storage
Store in a dry, cool & dark.
FDA Disclaimer Statement
Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
FSSAI (Food Safety and Standards Authority of India) Lic.No.: 20817018000147
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Artemisia Annua Extract Powder by Herbadiet label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Artemisia Annua Extract Powder by Herbadiet
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size500 mg Dosage formPowder Amounts shown are per serving.
Artemisia annua Extract, Powder
Interacts with889 drugs
Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studie...
Artemisia annua Extract, Powder monograph & interactionsArtemisia Annua Extract Powder by Herbadiet Drug Interactions
HelloPharmacist Interaction Report
Artemisia Annua Extract Powder by Herbadiet has documented interactions with medications, primarily through how its active ingredient affects your liver and how your body processes certain drugs.
Read the full breakdown — every affected drug type, severity by severity
The most serious concern is with hepatotoxic drugs—medications that can stress or damage the liver. Sweet Annie (the common name for Artemisia annua) itself can affect the liver, so taking it alongside drugs known to do the same might compound that risk.
This is rated Moderate severity.
Sweet Annie also interacts with drugs broken down by two liver enzymes called CYP3A4 and CYP2B6 (both Moderate severity). The research shows mixed signals: one compound in Sweet Annie (artemisinin) appears to speed up these enzymes, but the whole extract seems to slow them down.
Either way, the result is that your body might process these medications differently—sometimes faster, sometimes slower—which can change how well they work or how strong their effects are.
Altogether, these interactions span 890 individual medications. Before you start this product, run your exact medications through the search tool on this page, especially if you take any drugs for the liver, heart, or brain.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Artemisia Annua Extract Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Artemisia Annua Extract Powder interact with 889 drugs. Click any drug to see the details.
1 of the 1 ingredient in Artemisia Annua Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Artemisia annua Extract, Powder
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Abacavir, Lamivudine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Artemisia Annua Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Artemisia Annua Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Artemisia Annua Extract, Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Artemisia Annua Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Artemisia annua Extract, Powder
Cytochrome P450 2B6 (Cyp2B6) Substrates
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP2B6, possibly increasing CYP2B6 activity by 1.6-fold. However, Sweet Annie extract seems to inhibit the activity of CYP2B6 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP2B6 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP3A4, possibly increasing CYP3A4 activity by 1.9-fold. However, Sweet Annie extract seems to inhibit the activity of CYP3A4 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP3A4 substrates.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
There is some concern that Sweet Annie can adversely affect the liver.
Brand information
Manufacturer and brand details for Artemisia Annua Extract Powder, from the product label.
Herbadiet
See all Herbadiet products- Name
- Arkure Health Care
- Street Address
- 11, Sector - 14
- City
- Rohtak
- State
- Haryana
- ZipCode
- 124001
- Web Address
- www.herbadiet.in
Artemisia Annua Extract Powder by Herbadiet: Common Questions
Does Artemisia Annua Extract Powder by Herbadiet interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant or breastfeeding?
What are the most common side effects?
Does this actually work for hay fever?
Why is this product so much cheaper than antimalarial artemisinin drugs?
How long can I safely take this?
What's artemisinin, and is it in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Artemisia Annua Extract Powder is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Artemisia Annua Extract Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Artemisia Annua Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sweet Annie 11 references
- Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects. J Ethnopharmacol 2000;73:487-93. PubMed
- Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop Med Hyg 2004;70:128-32. DOI
- Centers for Disease Control and Prevention (CDC). Hepatitis temporally associated with an herbal supplement containing artemisinin-Washington, 2008. MMWR Morb Mortal Wkly Rep 2009;58:854-8.
- Xing J, Kirby BJ, Whittington D, et al. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug Metabl Dispos 2012;40(9):1757-64. PubMed
- Savage RL, Hill GR, Barnes J, Kenyon SH, Tatley MV. Suspected hepatotoxicity with a supercritical carbon dioxide extract of Artemisia annua in grapeseed oil used in New Zealand. Front Pharmacol. 2019;10:1448. PubMed
- Ruperti-Repilado FJ, Haefliger S, Rehm S, et al. Danger of herbal tea: a case of acute cholestatic hepatitis due to Artemisia annua tea. Front Med (Lausanne). 2019;6:221. PubMed
- Yang J, Shen Z, Liu L, et al. Clinical efficacy and safety of Artesimia annua-Sublingual immunotherapy in seasonal allergic rhinitis patients based on different intervention time. Int Arch Allergy Immunol 2022;183(8):852-859.
- Kane NF, Kiani BH, Desrosiers MR, Towler MJ, Weathers PJ. Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro. J Ethnopharmacol 2022. DOI
- Feng Y, Cao Y, Liu Y, et al. Clinical efficacy and safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia-induced rhinoconjunctivitis. Am J Otolaryngol 2023;44(5):103942. PubMed
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