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Dietary supplement

Asparagus Extract Ingredients & Drug Interactions

by Enzymatic Therapy

Asparagus Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Asparagus Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Asparagus Extract is a dietary supplement by Enzymatic Therapy with 1 active ingredient. Its ingredients are commonly taken for mild fluid retention (diuretic), urinary tract support, digestive health and fiber.Based on those ingredients, 76 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Asparagus (Asparagus officinalis) rhizome extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Asparagus Extract by Enzymatic Therapy

Ask about any prescription or over-the-counter medication and we check it for interactions with Asparagus Extract by Enzymatic Therapy — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Asparagus Extract by Enzymatic Therapy

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: asparagus (Asparagus officinalis) rhizome extract — the underground stem of the asparagus plant in concentrated form. The inactive ingredients are cellulose (a plant fiber), a vegetable polysaccharide capsule, and magnesium stearate (a flow agent).

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: potent detoxifier supporting urinary tract function.
  • We looked for evidence on: Urinary tract infections (UTIs), urinary tract health, detoxification, fluid retention.
  • The closest evidence on file: Asparagus is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs) (Natural Medicines).

The evidence for asparagus extract isn't established in our data. Effectiveness ratings for acne, cancer, constipation, high blood pressure, intestinal parasites, and kidney stones all show insufficient reliable evidence — meaning there isn't enough solid research yet to say whether it works for any of these conditions.

The evidence, ingredient by ingredient Asparagus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Asparagus as a food is generally well tolerated, but concentrated extracts like this one are less studied. Safety data advises caution with medicinal doses of asparagus extract — they haven't been proven safe the way the food has.

Allergic reactions are possible, especially in people sensitive to the lily family (onions, garlic, leeks, chives); symptoms can range from itchy eyes and a runny nose to hives, difficulty swallowing, difficulty breathing, and in rare cases anaphylaxis. One clinical trial of a combination product containing asparagus root caused side effects — constipation, belly pain and bloating, nausea, dry mouth, gallbladder complaints, and gout — in a portion of participants, though it's unclear whether asparagus or the other ingredient was responsible.

Side effects, ingredient by ingredient Asparagus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Asparagus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 76 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your medications if you take lithium (a mood stabilizer) or diuretic drugs (water pills for blood pressure or fluid buildup). Both have Moderate-severity interactions with asparagus extract.

Use the medication checker on this page to look up your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for people interested in asparagus extract, but the evidence it works for any specific condition isn't clear yet. If you take lithium or diuretic medications, you'll need to check with your pharmacist first — don't start without clearing it.

Because the safety data for medicinal doses is limited, talk to your pharmacist before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Asparagus Extract, straight from the product label.

Brand Enzymatic Therapy
Barcode (UPC) 763948088263
Net contents 60 Veg Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2013
DSLD ID 24638
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Asparagus Extract by Enzymatic Therapy, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
763948088263
IngredientAmount% DV
Asparagus (Asparagus officinalis) rhizome extract170 mg--

Other ingredients: Cellulose, Vegetable Polysaccharide Capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Asparagus Extract is a potent detoxifier that nutritionally supports urinary tract function.

This product contains natural ingredients; color variations are normal. ETI is an FDA-registered Drug Establishment.

Supports healthy fluid balance and urinary tract function

KIDNEY/URINARY

Formulation

Contains no sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, preservatives, or ingredients of animal origin.

Seals/Symbols

VEGETARIAN

LABORATORY TESTED PURITY, SAFETY & PERFORMANCE

Enzymatic Therapy What Better Feels Like(R)

General

LC08826.A05

FDA Disclaimer Statement

THIS STATEMENT HAS NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Recommendations: One capsule in the morning and evening.

Precautions

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Asparagus Extract by Enzymatic Therapy label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Asparagus Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Asparagus Extract by Enzymatic Therapy

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Asparagus (Asparagus officinalis) rhizome extract

Interacts with
76 drugs
170 mg per serving

Asparagus is a nutritious vegetable that is safe and healthy to eat as part of a normal diet. Most of its claimed medicinal benefits, such as use as a...

Asparagus (Asparagus officinalis) rhizome extract monograph & interactions

Other (inactive) ingredients: Cellulose, Vegetable Polysaccharide Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Asparagus Extract by Enzymatic Therapy Drug Interactions

Want to check YOUR meds against Asparagus Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
76Drugs
76 Moderate

Ingredients driving the most interactions

Asparagus (Asparagus officinalis) rhizome extract 76

Individual Drug Interactions

The ingredients in Asparagus Extract interact with 76 drugs. Click any drug to see the details.

1 of the 1 ingredient in Asparagus Extract interact with drugs. Each result below shows which ingredient is responsible. Asparagus (Asparagus officinalis) rhizome extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Asparagus Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Asparagus (Asparagus officinalis) rhizome extract2 drug types · 76 drugs

Diuretic Drugs

Theoretically, asparagus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus root extracts have diuretic effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, asparagus root might cause diuresis, reducing lithium clearance.
Animal studies show that asparagus root extracts have diuretic effects. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Asparagus (Asparagus officinalis) rhizome extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Asparagus Extract, from the product label.

Enzymatic Therapy

Name
Enzymatic Therapy, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1.800.783.2286
Web Address
enzy.com
Pharmacist Counseling Corner

Asparagus Extract by Enzymatic Therapy: Common Questions

Does Asparagus Extract by Enzymatic Therapy interact with any medications?
Yes. Based on its ingredients, Asparagus Extract has a known interaction with 76 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Asparagus Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does asparagus extract actually work for anything?
The evidence in our data isn't clear. We have effectiveness ratings for acne, cancer, constipation, high blood pressure, intestinal parasites, and kidney stones — all showing insufficient reliable evidence. That means there's not enough solid research to say whether it works for any of these yet.
Is this safe if I'm pregnant or breastfeeding?
The data on file gives conflicting signals for pregnancy — one source says Likely Safe, another says Possibly Unsafe. For breastfeeding, Likely Safe is noted, but there isn't enough data to be certain. Talk with your doctor or pharmacist about what's right for you in your situation.
Can I have an allergic reaction to asparagus extract?
Yes, if you're sensitive to asparagus or other plants in the lily family (onions, garlic, leeks, chives), you can have allergic reactions — anything from itchy eyes and a runny nose to hives, throat tightness, trouble breathing, or rarely anaphylaxis. There have also been reports of skin reactions that return the same way each time you take it.
What's the difference between eating asparagus and taking this extract?
Eating asparagus as food is well tolerated and fine. This product is a concentrated extract in medicinal doses, which hasn't been studied as thoroughly. The safety data advises caution with medicinal amounts, so this isn't the same as just eating asparagus on your plate.
What inactive ingredients are in this capsule?
The inactive ingredients are cellulose, a vegetable polysaccharide capsule, and magnesium stearate. These are standard excipients — fillers and binders that hold the capsule together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Asparagus Extract label
Go deeper

The Full Monographs Behind Asparagus Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Asparagus

Interacts with 76 drugs

Asparagus is a nutritious vegetable that is safe and healthy to eat as part of a normal diet. Most of its claimed medicinal benefits, such as use as a diuretic or for urinary health, come fr...

Read the full Asparagus monograph →
Sources

Sources & How We Checked

Asparagus Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Asparagus 14 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Volz T, Berner D, Weigert C, et al. Fixed food eruption caused by asparagus. J Allergy Clin Immunol 2005;116:1390-2. PubMed
  4. Huang X, Kong L. Steroidal saponins from roots of Asparagus officinalis. Steroids 2006;71:171-6. PubMed
  5. Rodriguez R, Jaramillo S, Rodriguez G, et al. Antioxidant activity of ethanolic extracts from several asparagus cultivars. J Agric Food Chem 2005;53:5212-7. PubMed
  6. Rieker J, Ruzicka T, Neumann NJ, Homey B. Protein contact dermatitis to asparagus. J Allergy Clin Immunol 2004;113:354-5. PubMed
  7. Tabar AI, Alvarez-Puebla MJ, Gomez B, et al. Diversity of asparagus allergy: clinical and immunological features. Clin Exp Allergy 2004;34:131-6. PubMed
  8. Rademaker M, Yung A. Contact dermatitis to Asparagus officinalis. Australas J Dermatol 2000;41:262-3.
  9. Misico, R. I., Nicotra, V. E., Oberti, J. C., Barboza, G., Gil, R. R., and Burton, G. Withanolides and related steroids. Prog.Chem.Org.Nat.Prod. 2011;94:127-229.
  10. Hausen BM, Wolf C. 1,2,3-Trithiane-5-carboxylic acid, a first contact allergen from Asparagus officinalis (Liliaceae). Am J Contact Dermat 1996;7(1):41-46. PubMed
  11. Escribano MM, Munoz-Bellido FJ, Serrano P, et al. Acute urticaria after ingestion of asparagus. Allergy 1998;53(6):622-623. PubMed
  12. Chrubasik S, Droste C, Black A. Asparagus P(R) cannot compete with first-line diuretics in lowering the blood pressure in treatment-requiring antihypertensives. Phytother Res 2009;23:1345-6.
  13. Gaus BM, Scheiba N, Schäkel K. Asparagus-induced fixed food eruptions mimicking cutaneous lupus. Acta Derm Venereol 2014;94:731-2. PubMed
  14. Yanagi T, Shimizu H, Shimizu T. Occupational contact dermatitis caused by asparagus. Contact Dermatitis 2010;63:54. PubMed

See these in context on the Asparagus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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