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Dietary supplement

Astaxanthin 12 mg Ingredients & Drug Interactions

by Allergy Research Group

Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Astaxanthin 12 mg is a dietary supplement by Allergy Research Group with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Astaxanthin 12 mg by Allergy Research Group

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: astaxanthin 12 mg per softgel capsule. Astaxanthin is a carotenoid — a plant-based pigment with antioxidant properties — that your body may use for various roles related to aging and eye health, though the evidence for specific benefits is still being studied.

The softgel also contains inactive ingredients (safflower oil, vitamin E, bovine gelatin, glycerin, water, and medium chain triglyceride) that help deliver and preserve the active ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: antioxidant support for brain, eyes, muscles, skin and heart.
  • We looked for evidence on: Age-related cognitive decline, Age-related macular degeneration (AMD), Aging skin, Alzheimer disease, Athletic performance, Dry eye — and 4 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Aging skin, Alzheimer disease, Athletic performance, and more.

The evidence for astaxanthin's effectiveness isn't yet established in the data we hold. The supplement has been studied for age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome, but all of those areas currently have insufficient reliable evidence to rate how well it works.

That doesn't mean it won't help — it means more research is needed before we can say.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects reported orally are abdominal pain, diarrhea, and red-colored stools.

At the 12 mg dose in this product, side effects appear uncommon; higher doses (40 mg daily) have caused severe stomach pain in a small number of people. There isn't enough safety data to know whether astaxanthin is safe during pregnancy or while breastfeeding.

The safety data advises against use in both situations. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this supplement.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take astaxanthin, check whether you're on any drugs metabolized by CYP3A4 or CYP2B6 — two major liver enzymes. Both are rated Moderate severity.

If you take statins, certain blood pressure medications, immunosuppressants, antihistamines, or many other common drugs, they may fall into these categories. Use the medication checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin may be worth considering if you're interested in antioxidant support, but the evidence for specific health claims is still developing. Anyone taking medications metabolized by liver enzymes CYP3A4 or CYP2B6 should check their exact drugs with the tool on this page before starting.

Pregnant or breastfeeding women should avoid it. Talk with your pharmacist if you have questions about whether it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin 12 mg, straight from the product label.

Brand Allergy Research Group
Barcode (UPC) 713947783409
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 317587
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin 12 mg by Allergy Research Group, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
713947783409
IngredientAmount% DV
Astaxanthin12 mg--

Other ingredients: Safflower Oil, Vitamin E, Bovine Gelatin, Glycerin, Water, Medium Chain Triglyceride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Astaxanthin 12 mg AstaZine astaxanthin is derived from the organic microalgae Haematococcus pluvialis, grown under sunlight in controlled conditions. Astaxanthin has been shown to benefit the brain, eyes, muscles, skin, heart, blood vessels, and internal organs.

AstaZine from Pure Microalgae

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 1 softgel daily with meals, or as directed by a healthcare practitioner.

Seals/Symbols

Verified Natural Algae Astaxanthin NAXA

Brand IP Statement(s)

AstaZine AstaZine is a registered trademark of BGG.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. The product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

To report any adverse reactions, call 1-833-914-2097.

FDA Statement of Identity

Dietary Supplement

Formulation

Hypoallergenic

Storage

Store in a cool, dry place, tightly capped.

See for yourself

Astaxanthin 12 mg by Allergy Research Group label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Astaxanthin 12 mg by Allergy Research Group

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Astaxanthin

Interacts with
671 drugs
12 mg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Safflower Oil, Vitamin E, Bovine Gelatin, Glycerin, Water, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin 12 mg by Allergy Research Group Drug Interactions

Want to check YOUR meds against Astaxanthin 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Astaxanthin 12 mg, from the product label.

Allergy Research Group

See all Allergy Research Group products
Name
Allergy Research Group
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800.545.9960
Web Address
www.allergyresearchgroup.com
Pharmacist Counseling Corner

Astaxanthin 12 mg by Allergy Research Group: Common Questions

Does Astaxanthin 12 mg by Allergy Research Group interact with any medications?
Yes. Based on its ingredients, Astaxanthin 12 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take astaxanthin if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way, so the safety data advises against it in both pregnancy and breastfeeding. If you're in either situation, talk with your doctor or pharmacist for personalized advice before taking this supplement.
What side effects might I notice?
Astaxanthin is generally well tolerated, but the most common side effects are abdominal pain, diarrhea, and red-colored stools. These are uncommon at this dose, though higher doses have caused more severe stomach pain in some people.
Does astaxanthin actually work for anti-aging or eye health?
The evidence isn't established yet in the data we hold. Astaxanthin has been studied for conditions like age-related macular degeneration and aging skin, but there's currently insufficient reliable evidence to say how well it works for those purposes. More research is needed.
What exactly is astaxanthin?
Astaxanthin is a carotenoid — a type of pigment found in plants with antioxidant properties. It's the compound that gives certain seafood and algae their reddish color.
Does this product have any fillers or extra ingredients?
Yes, the softgel contains inactive ingredients: safflower oil, vitamin E, bovine gelatin, glycerin, water, and medium chain triglyceride. These help deliver and stabilize the active astaxanthin but aren't the main ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin 12 mg label
Sources

Sources & How We Checked

Astaxanthin 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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