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Dietary supplement

Astaxanthin 12 mg Ingredients & Drug Interactions

by Double Wood Supplements

Astaxanthin 12 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astaxanthin 12 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astaxanthin 12 mg is a dietary supplement by Double Wood Supplements with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AstaReal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astaxanthin 12 mg by Double Wood Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Astaxanthin 12 mg by Double Wood Supplements — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Astaxanthin 12 mg by Double Wood Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: AstaReal astaxanthin at 12 mg per softgel. Astaxanthin is a red pigment from algae that acts as an antioxidant in your body.

The softgel is made with extra virgin olive oil, gelatin, glycerin, and water to deliver the ingredient.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Astaxanthin product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“Antioxidant support and overall wellness”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for astaxanthin isn't yet established in our data. We hold insufficient reliable evidence to rate it for age-related cognitive decline, macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome — the areas we've reviewed.

That doesn't mean it doesn't work; it means the research so far hasn't been strong enough to draw firm conclusions.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated, though long-term safety data are limited. The most common side effects from oral doses are abdominal pain, diarrhea, and red-colored stools.

In studies, the 12 mg dose (or similar) caused increased bowel movements and red stool in a small number of participants; a much higher 40 mg dose caused severe stomach pain in two patients. There isn't enough safety data to know whether astaxanthin is safe during pregnancy or while breastfeeding.

Talk with your doctor or pharmacist before using it if you're pregnant or nursing.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any medications that are metabolized by the liver enzymes CYP3A4 and CYP2B6 before adding this product. That includes many blood pressure medications, statins, and immunosuppressants.

Although the interaction is theoretical rather than proven in humans, it's worth verifying your specific drugs with the interaction tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin is generally well tolerated as an oral supplement, but the research on what it actually does isn't conclusive yet. If you take medications broken down by your liver—especially blood pressure drugs, statins, or immune-modulating medicines—check with us first.

Pregnant or breastfeeding? Talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin 12 mg, straight from the product label.

Brand Double Wood Supplements
Barcode (UPC) 850033272178
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 315588
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin 12 mg by Double Wood Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
850033272178
IngredientAmount% DV
AstaReal12 mg--

Other ingredients: Extra Virgin Olive Oil, Gelatin, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Product information: Double Wood's AstaReal Astaxanthin is a natural and patented form of Astaxanthin that is extracted from Haematococcus pluvialis algae. AstaReal Astaxanthin is a patented ingredient backed by over 150 studies, 70 of which are human clinical studies.

Astaxanthin Astareal 12 mg per softgel

Brand IP Statement(s)

AstaReal is a registered trademark of Fuji Chemical Industries Co., Ltd.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 softgel per day. For best results take with a meal.

Storage

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature

Seals/Symbols

Proudly Made in USA

Formulation

Made with Non-GMO Ingredients Gluten Free

70+ human clinical studies

Sourced and made in the USA

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Discontinue use and consult your doctor immediately if any adverse reactions occur. Do not use Astaxanthin and operate heavy machinery until you know how it affects you.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Astaxanthin 12 mg by Double Wood Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astaxanthin 12 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astaxanthin 12 mg by Double Wood Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

AstaReal

Interacts with
671 drugs
12 mg per serving Form: Astaxanthin

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

AstaReal monograph & interactions

Other (inactive) ingredients: Extra Virgin Olive Oil, Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin 12 mg by Double Wood Supplements Drug Interactions

Want to check YOUR meds against Astaxanthin 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

AstaReal 671

Individual Drug Interactions

The ingredients in Astaxanthin 12 mg interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Astaxanthin 12 mg interact with drugs. Each result below shows which ingredient is responsible. AstaReal

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AstaReal2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
AstaReal full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astaxanthin 12 mg, from the product label.

Double Wood Supplements

See all Double Wood Supplements products
Name
Double Wood LLC
Street Address
3510 Scotts Ln Ste 219
City
Philadelphia
State
PA
ZipCode
19129-1573
Web Address
www.doublewoodsupplements.com
Pharmacist Counseling Corner

Astaxanthin 12 mg by Double Wood Supplements: Common Questions

Does Astaxanthin 12 mg by Double Wood Supplements interact with any medications?
Yes. Based on its ingredients, Astaxanthin 12 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is astaxanthin and why is it in this product?
Astaxanthin is a red pigment from algae that acts as an antioxidant. It's included at 12 mg per softgel, though the evidence for what it actually does for your health isn't conclusive yet based on current research.
What side effects might I experience?
Most people tolerate it well. The most common side effects are abdominal pain, diarrhea, and red-colored stools. In studies, these were uncommon, but they're worth knowing about before you start.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data either way. It's best to avoid it during pregnancy and breastfeeding and talk with your doctor or pharmacist about whether it's right for you in those situations.
How does this interact with my medications?
Lab research shows astaxanthin may speed up how your liver breaks down certain drugs—particularly those processed by CYP3A4 and CYP2B6 enzymes. This could lower their effectiveness, though it hasn't been proven in humans. Check your specific medications using the tool on this page.
Is this supplement proven to work?
Not yet. We have insufficient reliable evidence to rate astaxanthin for the conditions we've reviewed—aging skin, cognitive decline, macular degeneration, Alzheimer disease, athletic performance, and carpal tunnel syndrome.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astaxanthin 12 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin 12 mg label
Go deeper

The Full Monographs Behind Astaxanthin 12 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Astaxanthin 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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