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Dietary supplement

Astaxanthin 4 mg Ingredients & Drug Interactions

by CHK Nutrition

Astaxanthin 4 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astaxanthin 4 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astaxanthin 4 mg is a dietary supplement by CHK Nutrition with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astaxanthin 4 mg by CHK Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Astaxanthin 4 mg by CHK Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Astaxanthin 4 mg by CHK Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: astaxanthin, a 4 mg dose per softgel. Astaxanthin is a naturally occurring compound studied for possible benefits in eye health, brain aging, skin, and athletic recovery.

The softgel capsule is made from vegetarian material and filled with extra virgin olive oil, mixed tocopherols (a form of vitamin E), and rosemary extract — these are inactive ingredients that help deliver and preserve the astaxanthin.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Antioxidant protection for eyes, skin and cardiovascular system.
  • We looked for evidence on: Age-related macular degeneration (AMD), Aging skin, Athletic performance, Dry eye, Exercise-induced muscle damage, Exercise-induced muscle soreness — and 4 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Athletic performance, Heart failure, Dry eye, and more.

The evidence we have for astaxanthin is still being built. For age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome, the reliable evidence to rate whether it works is insufficient.

That means the science isn't settled yet — it doesn't mean it's ineffective, just that we don't have strong proof in hand right now.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are still limited. The most common side effects reported are abdominal pain, diarrhea, and red-colored stools.

At higher doses (40 mg daily), a small number of users experienced severe stomach or abdominal pain; at the standard 6 mg dose, a few people reported increased bowel movements and red stools. There isn't enough safety data during pregnancy or while breastfeeding, so the safety data advises against use in both situations.

If you're pregnant, planning pregnancy, or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this product, check with your pharmacist if you take any Moderate-severity medications broken down by the liver enzymes CYP3A4 or CYP2B6. These include many statins, some blood pressure medications, certain antihistamines, and immunosuppressant drugs.

Astaxanthin may theoretically lower how well these drugs work — though this effect hasn't yet been confirmed in humans.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin 4 mg is an option if you're curious about a supplement studied for aging-related concerns — but the evidence on whether it actually works isn't yet solid. The main thing to do before you start is check your medications against the CYP3A4 and CYP2B6 interaction list with your pharmacist, especially if you take statins, blood pressure drugs, or immunosuppressants.

It's not a good fit if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin 4 mg, straight from the product label.

Brand CHK Nutrition
Barcode (UPC) 787500021321
Net contents 60 Vegetarian Softgel(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228640
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin 4 mg by CHK Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Softgel(s)
Maximum serving Sizes:
1 Vegetarian Softgel(s)
UPC/BARCODE
787500021321
IngredientAmount% DV
Astaxanthin4 mg--

Other ingredients: Vegetarian Softgel, extra virgin Olive Oil, Mixed Tocopherols, Rosemary extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Contains no sugar, salt, dairy, wheat, gluten, soy, preservatives, artificial colors or flavors.

Powerful antioxidant protection for eyes, skin and cardiovascular system

Quality and potency guaranteed

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, adults take one (1) vegetarian softgel one (1) to three (3) times daily, or as directed by a health care professional.

Storage

Store in a cool, dry place and away from direct light.

Precautions

Keep out of reach of children.

Contains soy (a non-GMO source of natural tocopherols that are used to prevent oxidant).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

New day. Fresh start. Better health.

FDA Statement of Identity

Dietary Supplement

Formula

Astaxanthin is one of nature's most potent antioxidants and free radical scavengers. It has the unique ability to cross the brain/blood barrier into cells in the eye and the nervous system, and is capable of preventing oxidative damage to both kinds of tissues. Astaxanthin is many times more potent than many common antioxidants, including Vitamin C and E, and beta carotene. In fact, one scientific study showed that astaxanthin is 6000 times better at neutralizing singlet oxygen free radicals than Vitamin C.e more common form, Vitamin K1 (phylloquinone).

Brand IP Statement(s)

The eye protective benefits of astaxanthin are shown in US Patent No. 5,527,533. Zanthin brand astaxanthin is made by a proprietary Supercritical CO2 process. Zanthin is a registered trademark of Valensa.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Astaxanthin 4 mg by CHK Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astaxanthin 4 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astaxanthin 4 mg by CHK Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Astaxanthin

Interacts with
671 drugs
4 mg per serving Form: Zanthin brand Haematococcus pluvialis extract

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Vegetarian Softgel, Extra virgin Olive Oil, Mixed Tocopherols, Rosemary extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin 4 mg by CHK Nutrition Drug Interactions

Want to check YOUR meds against Astaxanthin 4 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Astaxanthin 671

Individual Drug Interactions

The ingredients in Astaxanthin 4 mg interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Astaxanthin 4 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin 4 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astaxanthin 4 mg, from the product label.

CHK Nutrition

See all CHK Nutrition products
Name
CHK Nutrition
Street Address
3930 E Calvary Rd
City
Duluth
State
MN
ZipCode
55803
Phone Number
877-538-8388
Pharmacist Counseling Corner

Astaxanthin 4 mg by CHK Nutrition: Common Questions

Does Astaxanthin 4 mg by CHK Nutrition interact with any medications?
Yes. Based on its ingredients, Astaxanthin 4 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin 4 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does astaxanthin actually work for wrinkles or eye health?
The reliable evidence to say whether it works for aging skin or age-related macular degeneration isn't established yet. The same goes for cognitive decline and Alzheimer disease — these are areas being studied, but we don't have solid proof either way right now.
Will this give me red poop?
It's possible. Red or reddish-colored stools have been reported by some people taking astaxanthin, especially at higher doses. It's harmless — just the astaxanthin's pigment passing through — but it can be startling if you're not expecting it.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way, so the safety data advises against it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether it's right for your situation.
Is astaxanthin a natural ingredient?
Yes. Astaxanthin is a naturally occurring pigment found in certain algae, salmon, and other seafood — it's what gives them their reddish color.
What if astaxanthin upsets my stomach?
Abdominal pain and diarrhea are the most commonly reported side effects. If you experience either, stop the supplement and talk to your pharmacist about whether you should try a lower dose or a different approach.
How long does it take astaxanthin to work?
We don't have reliable evidence on how long it takes or whether it works for most of the conditions it's marketed for, so we can't answer that from the data we have.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin 4 mg label
Go deeper

The Full Monographs Behind Astaxanthin 4 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Astaxanthin 4 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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