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Dietary supplement

Astaxanthin & Black Currant Ingredients & Drug Interactions

by Higher Nature

Astaxanthin & Black Currant label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astaxanthin & Black Currant against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astaxanthin & Black Currant is a dietary supplement by Higher Nature with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 775 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are pure Astaxanthin, Blackcurrant fruit extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astaxanthin & Black Currant by Higher Nature

Ask about any prescription or over-the-counter medication and we check it for interactions with Astaxanthin & Black Currant by Higher Nature — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Astaxanthin & Black Currant by Higher Nature

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains three active ingredients. Pure astaxanthin is a carotenoid pigment derived from algae, tomato powder is a concentrated tomato source, and blackcurrant fruit extract comes from the black currant berry.

The product also contains several inactive ingredients — fillers, binders, and capsule materials — including hydroxypropyl methylcellulose, silicon dioxide, magnesium stearate, and rosemary leaf extract.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Skin and eye health support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Aging skin, Atopic dermatitis (eczema), Cataracts, Dry eye, Sunburn — and 3 related terms.
  • The closest evidence on file: Tomato is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Tomato is rated "Insufficient Reliable Evidence To Rate" for Cataracts.
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Aging skin, Dry eye, Sunburn.

The evidence for what this product does is not established in the data we hold. Astaxanthin has been studied for age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome, but the data shows insufficient reliable evidence to rate it for any of these.

Tomato powder (lycopene source) has been studied for bladder cancer, breast cancer, and diabetes, but found possibly ineffective for the first two and insufficient evidence for diabetes and other conditions. Black currant has been studied for Alzheimer disease, liver disease, upper respiratory infections, cough, and eczema, but again the evidence is insufficient to rate.

If you're considering this product for a specific health goal, check with your pharmacist or doctor about whether the evidence supports its use.

The evidence, ingredient by ingredient Astaxanthin Tomato Black Currant

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are abdominal pain, diarrhea, and red-colored stools — a harmless color change.

At higher doses (40 mg daily), some patients have experienced severe stomach pain. Tomato powder as food is safe; concentrated supplements are less studied but generally tolerated.

Black currant as a food is probably fine, but concentrated supplements lack robust safety data and should be used with caution. The data advises against astaxanthin during pregnancy and breastfeeding due to insufficient safety information.

Side effects, ingredient by ingredient Astaxanthin Tomato Black Currant

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Astaxanthin, Black Currant.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 776 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you're on any drugs metabolized by your liver's CYP3A4 or CYP2B6 enzymes (statins, some blood pressure drugs, immunosuppressants, and antidepressants are common ones — there are many more). Also check if you take blood thinners (anticoagulants) or antiplatelet drugs like aspirin, or if you're on phenothiazines (psychiatric medications).

The astaxanthin and black currant in here may affect how these drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for someone interested in antioxidant support who has checked their medications for interactions — especially if you take drugs metabolized by your liver, blood thinners, or psychiatric medications. If you're pregnant, breastfeeding, or on any prescription medication, talk with your pharmacist before you start.

Expect possible mild digestive side effects.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin & Black Currant, straight from the product label.

Brand Higher Nature
Barcode (UPC) 5031013102769
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 223332
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin & Black Currant by Higher Nature, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
UPC/BARCODE
5031013102769
IngredientAmount% DV
pure Astaxanthin4 mg--
Tomato powder622.5 mg--
Blackcurrant fruit extract100 mg--

Other ingredients: Tomato powder, Hydroxypropyl Methylcellulose, Haematococcus pluvialis, Silicon Dioxide, Magnesium Stearate, Mixed Carotenoids, Rosemary leaf standardized extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Free From: Artificial colours, flavourings or preservatives, dairy products, gluten, lactose, salt, sugar, wheat, yeast.

For skin & eyes Advanced formula optimal benefit

Vegetarian and vegan

Storage

Storage: Store in a cool, dry, steam free environment out of reach of children.

Precautions

Storage: Store in a cool, dry, steam free environment out of reach of children.

Do not exceed recommended daily intake. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

General Statements

This product is not tested on animals.

Everyday essentials

FDA Statement of Identity

Food Supplement

Formula

Contains astaxanthin, a powerful carotenoid. Astaxanthin for the skin & eyes. Blackcurrants contain anthocyanidins, polyphenols and vitamin C.

Suggested/Recommended/Usage/Directions

Directions: Adults and children over 8 years take 2 capsules a day with a meal. Do not exceed recommended daily intake.

Best absorbed when taken with a meal.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Astaxanthin & Black Currant by Higher Nature label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astaxanthin & Black Currant label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astaxanthin & Black Currant by Higher Nature

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pure Astaxanthin

Interacts with
671 drugs
4 mg per serving Form: Haematococcus pluvialis

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Pure Astaxanthin monograph & interactions

Tomato powder

No known
interactions
622.5 mg per serving Form: Lycopene

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people...

Tomato powder monograph & interactions

Blackcurrant fruit extract

Interacts with
140 drugs
100 mg per serving

Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjo...

Blackcurrant fruit extract monograph & interactions

Other (inactive) ingredients: Tomato powder, Hydroxypropyl Methylcellulose, Haematococcus pluvialis, Silicon Dioxide, Magnesium Stearate, Mixed Carotenoids, Rosemary leaf standardized extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin & Black Currant by Higher Nature Drug Interactions

Want to check YOUR meds against Astaxanthin & Black Currant?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
775Drugs
775 Moderate

Ingredients driving the most interactions

pure Astaxanthin 671
Blackcurrant fruit extract 140

Individual Drug Interactions

The ingredients in Astaxanthin & Black Currant interact with 775 drugs. Click any drug to see the details.

2 of the 3 ingredients in Astaxanthin & Black Currant interact with drugs. Each result below shows which ingredient is responsible. pure Astaxanthin Blackcurrant fruit extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin & Black Currant with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

pure Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
pure Astaxanthin full monograph & interactions

Blackcurrant fruit extract2 drug types · 140 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Gamma-linolenic acid (GLA), a constituent of black currant seed oil, appears to have antiplatelet effects.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, black currant seed oil might increase the risk of seizure in patients receiving phenothiazines.
Black currant seed oil contains gamma-linolenic acid (GLA). There is some concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines, although there is no evidence that black currant seed oil causes seizures. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with GLA, although none experienced an actual seizure. In another report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily, which contains GLA, was added. One of these patients had a prior history of seizures.

Likelihood Possible Evidence D
Blackcurrant fruit extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astaxanthin & Black Currant, from the product label.

Higher Nature

See all Higher Nature products
Name
Higher Nature Ltd
Street Address
10 Discovery Way
City
Horam TN21 0GE
State
East Sussex
Web Address
highernature.com
Pharmacist Counseling Corner

Astaxanthin & Black Currant by Higher Nature: Common Questions

Does Astaxanthin & Black Currant by Higher Nature interact with any medications?
Yes. Based on its ingredients, Astaxanthin & Black Currant has a known interaction with 775 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin & Black Currant contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data for astaxanthin advise against it during pregnancy and breastfeeding. Tomato powder is likely safe in food amounts during pregnancy and breastfeeding, but black currant concentrated supplements lack enough safety data. Talk with your doctor or pharmacist for personalized advice before taking this product if you're pregnant or nursing.
What side effects should I watch for?
The most common ones are abdominal pain, diarrhea, and red-colored stools — the color change is harmless. At the doses in this product, side effects are generally mild. If you experience severe stomach pain, stop and talk to your pharmacist.
Is astaxanthin effective for anti-aging or brain health?
The evidence we hold shows insufficient reliable evidence to rate astaxanthin for anti-aging, macular degeneration, cognitive decline, or Alzheimer disease. If that's why you're interested in it, check with your pharmacist about what the current evidence actually supports.
Does this product have a lot of fillers?
Like most capsules, it contains inactive ingredients — binders, capsule material, and some other excipients. The three active ingredients are astaxanthin, tomato powder, and blackcurrant fruit extract.
Is black currant extract safe to take every day?
The berry itself as food is fine, but concentrated supplements haven't been studied as thoroughly for long-term daily use. A small number of trial participants taking black currant seed oil reported mild diarrhea early on. Use caution and talk to your pharmacist if you're taking it long-term.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astaxanthin & Black Currant is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin & Black Currant label
Go deeper

The Full Monographs Behind Astaxanthin & Black Currant’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph → Herb & supplement monograph

Tomato

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supple...

Read the full Tomato monograph → Herb & supplement monograph

Black Currant

Interacts with 140 drugs

Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjoyed safely as a food and is popular as a...

Read the full Black Currant monograph →
Sources

Sources & How We Checked

Astaxanthin & Black Currant's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Tomato 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Asero R, Mistrello G, Amato S. Airborne allergy to tomato proteins. Allergy. 2010;65(12):1626-7. PubMed
  3. Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed

See these in context on the Tomato monograph →

Black Currant 6 references
  1. Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty A PubMed
  2. Fa-lin Z, Zhen-yu W, Yan H, et al. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. Phytother Res 2010;24 Suppl 2:S209-13. PubMed
  3. Holman CP and Bell AF. A trial of evening primrose oil in the treatment of chronic schizophrenia. J Orhtomolecular Psych 1983;12:302-304.
  4. Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. PubMed
  5. Norred, C. L. and Brinker, F. Potential coagulation effects of preoperative complementary and alternative medicines. Alt Ther 2001;7(6):58-67.
  6. Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3. PubMed

See these in context on the Black Currant monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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