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Dietary supplement

Astragalus Root Ingredients & Drug Interactions

by Cedar Bear

Astragalus Root label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astragalus Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astragalus Root is a dietary supplement by Cedar Bear with 1 active ingredient. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astragalus Root by Cedar Bear

Ask about any prescription or over-the-counter medication and we check it for interactions with Astragalus Root by Cedar Bear — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Astragalus Root by Cedar Bear

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.50 mL) without saying how much of each component you get.

This product contains one active ingredient: Astragalus, a traditional botanical supplement. It's formulated as a liquid with vegetable glycerin and purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astragalus product and its label doesn't state a use — see Astragalus's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold shows insufficient reliable evidence to rate astragalus for the conditions tested, including hay fever (allergic rhinitis), lack of menstruation (amenorrhea), aplastic anemia, angina, asthma, and beta-thalassemia. That doesn't mean it doesn't work for these or other uses — just that the research on file doesn't establish clear effectiveness yet.

The evidence, ingredient by ingredient Astragalus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astragalus is generally well tolerated in the short term in healthy adults, though quality human safety data is limited. The safety data advises against using it during pregnancy or while breastfeeding due to insufficient reliable information.

Adverse effects from clinical trials and research include rare reports of chest tightness (lacunar angina), dizziness, palpitations, rash, and itching — though not all of these may have been caused by astragalus itself. Most of these were seen in intravenous (IV) studies; this product is a liquid taken by mouth, which is a different route.

Side effects, ingredient by ingredient Astragalus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take immunosuppressants (like azathioprine or mycophenolate), lithium, cyclophosphamide, or diabetes medications. These all have Moderate interactions documented with astragalus.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astragalus is a single-ingredient liquid supplement that's generally well tolerated in the short term, but it does interact with several medication types — most importantly immunosuppressants, lithium, and diabetes drugs. If you take any regular medications, check them against the interaction tool on this page or talk with your doctor or pharmacist before starting.

Pregnancy and breastfeeding are not recommended without medical guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astragalus Root, straight from the product label.

Brand Cedar Bear
Barcode (UPC) 834711001076
Net contents 30 mL; 1 fl. Oz.
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 236982
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astragalus Root by Cedar Bear, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
0.5 mL
Servings per container
60
UPC/BARCODE
834711001076
IngredientAmount% DV
Proprietary Blend0.5 mL--
Astragalus0 NP--

Other ingredients: USP Grade Vegetable Glycerin, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Manufactured in the USA

True Alcohol Free Sugar Free Gluten Free

Vegan

Suggested/Recommended/Usage/Directions

Suggested use: .5 mL (10 drops) 1 to 3 times a day, or as needed. Shake well.

Precautions

Note: Consult your physician before use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practices K (Kosher)

Formula

K (Kosher)

Astragalus membranaceus

General Statements

Herbal Single

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Astragalus Root by Cedar Bear label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astragalus Root label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astragalus Root by Cedar Bear

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Proprietary Blend

0.5 mL per serving

Other (inactive) ingredients: USP Grade Vegetable Glycerin, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astragalus Root by Cedar Bear Drug Interactions

Want to check YOUR meds against Astragalus Root?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Astragalus 208

Individual Drug Interactions

The ingredients in Astragalus Root interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Astragalus Root interact with drugs. Each result below shows which ingredient is responsible. Astragalus

Each ingredient & the kinds of drugs it affects

For each ingredient in Astragalus Root with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astragalus Root, from the product label.

Cedar Bear

See all Cedar Bear products
Name
Cedar Bear Naturales INC
Street Address
PO Box 158
City
Roosevelt
State
UT
ZipCode
84066
Phone Number
1-888-854-3727
Web Address
Cedarbear.com
Pharmacist Counseling Corner

Astragalus Root by Cedar Bear: Common Questions

Does Astragalus Root by Cedar Bear interact with any medications?
Yes. Based on its ingredients, Astragalus Root has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astragalus Root contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Astragalus Root while I'm pregnant or breastfeeding?
The safety data advises against it. There isn't enough reliable information to know whether it's safe during pregnancy or while breastfeeding, so it's best avoided in both. Talk with your doctor or pharmacist about whether it's right for you in these situations.
What's the concern with astragalus and immunosuppressants?
Astragalus seems to stimulate your immune system, which theoretically could work against medications designed to suppress it — like those used after a transplant or for certain autoimmune conditions. That's why checking with your doctor is important if you're on one of these drugs.
Does astragalus affect blood sugar?
Clinical research suggests astragalus might lower blood sugar (hypoglycemia) on its own. If you take diabetes medications, combining them with astragalus could increase that risk further, so your doctor should know before you start it.
Are there any reported side effects from astragalus?
Uncommon side effects reported in clinical trials include dizziness, palpitations, and rash, though these may not have been caused by astragalus itself. Most were seen in intravenous studies; this product is a liquid taken by mouth.
Is there evidence this works for allergies or asthma?
The evidence we hold shows insufficient reliable data to rate astragalus for hay fever (allergic rhinitis), asthma, or other conditions tested. That doesn't mean it doesn't work — just that the research on file doesn't establish effectiveness yet.
Can I take this long-term?
Safety data is limited mainly to short-term use in healthy adults. If you're considering long-term use, talk with your doctor or pharmacist about whether it's appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astragalus Root label
Go deeper

The Full Monographs Behind Astragalus Root’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph →
Sources

Sources & How We Checked

Astragalus Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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