Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Aswagandha Smoothie Booster Ingredients & Drug Interactions

by Organic Traditions

Aswagandha Smoothie Booster label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Aswagandha Smoothie Booster against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Aswagandha Smoothie Booster is a dietary supplement by Organic Traditions with 2 active ingredients. Its ingredients are commonly taken for stress and anxiety, sleep problems, fatigue and low energy.Based on those ingredients, 1,372 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Ashwagandha (Withania somnifera) Hydroethanolic extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Aswagandha Smoothie Booster by Organic Traditions

Ask about any prescription or over-the-counter medication and we check it for interactions with Aswagandha Smoothie Booster by Organic Traditions — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Aswagandha Smoothie Booster by Organic Traditions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This smoothie booster contains two forms of ashwagandha (Withania somnifera), each extracted differently: a hydroethanolic extract and a CO2 extract. That's 2 active ingredients total.

The product also contains silicon dioxide as an inactive ingredient (a flow agent).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: stress, anxiety, fatigue and general well-being.
  • We looked for evidence on: Stress, Anxiety, Generalized anxiety disorder (GAD), Fatigue, Psychological well-being, Insomnia — and 3 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD), Insomnia, Stress.
  • Also on file: Ashwagandha is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-related fatigue, Fatigue, Psychological well-being.

The evidence supports ashwagandha for a few conditions. It's possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder (GAD).

For bipolar disorder, the data we hold isn't strong enough to rate it one way or the other.

The evidence, ingredient by ingredient Ashwagandha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term, ashwagandha is generally well tolerated in healthy adults, but long-term safety data are limited and quality varies. The most common side effects are stomach-related — diarrhea, upset stomach, nausea, and vomiting — though these don't typically happen at standard doses.

Rare but serious concerns include liver damage and intracranial hemorrhage (bleeding in the brain). Drowsiness has also been reported.

During pregnancy, the safety data advises against it because ashwagandha is traditionally thought to risk miscarriage. While breastfeeding, there isn't enough safety information, so it's best avoided.

Side effects, ingredient by ingredient Ashwagandha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ashwagandha.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,373 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take drugs that stress the liver (hepatotoxic medications), CNS depressants or benzodiazepines, blood pressure medications, diabetes medications, thyroid hormones, immunosuppressants, or medications broken down by the liver enzyme CYP1A2. These are the medication types most likely to be affected by ashwagandha.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Ashwagandha may help with anxiety, stress, and sleep trouble. If you take any medications — especially for blood pressure, diabetes, anxiety, sedation, thyroid function, or immune suppression — check them against the interaction tool first.

Pregnant or breastfeeding folks should skip this product. Talk to your pharmacist before you start, especially if you have liver concerns or take multiple drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aswagandha Smoothie Booster, straight from the product label.

Brand Organic Traditions
Barcode (UPC) 627733004176
Net contents 1.15 oz.; 33 Gram(s)
Market status On market
Date entered into DSLD Aug 24, 2016
DSLD ID 63351
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aswagandha Smoothie Booster by Organic Traditions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.375 Gram(s)
Maximum serving Sizes:
0.75 Gram(s)
Servings per container
44
UPC/BARCODE
627733004176
IngredientAmount% DV
organic Ashwagandha (Withania somnifera) Hydroethanolic extract682.5 mg--
Organic Ashwagandha (Withania somnifera) CO2 extract37.5 mg--

Other ingredients: Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Organic Traditions is committed to offering nutrient dense superfoods from many healing traditions around the world.

Organic Traditions Herbal Water and Smoothie Booster concentrated powders offer a refreshing alternative to sugar-laden, artificially flavored beverages.

In order to represent the complete signature of the herb, Organic Traditions Herbal Smoothie Booster concentrated powders combine Supercritical CO2 extracts and Hydroethanolic extracts in an easy to use, semi-soluble powder form.

At Organic Traditions the desire to go green within is bound to a commitment to preserve and protect our precious planet.

ECO CERT BY ECOCERT ICO

General Statements

Discover over 100 superfoods and fuel yourself at the highest level possible.

Supercharge Your Water and Smoothies And Power your Life With The Wisdom Of Ashwagandha

Stay hydrated while boosting your water, favorite beverage or smoothie with the many benefits of these incredible herbs. Satisfy your thirst and ignite your being.*

Infuse Your Day With The Concentrated Power Of Ashwagandha An Easy To Use, Full Spectrum Powder Our proprietary full spectrum process gently extracts the full array of phytonutrients using a combination of supercritical CO2 extraction (fat soluble compounds) and hydroethanolic extraction (water soluble compounds) offering the complete signature of the herb in its most potent and pure form. No harsh solvents or high heat are used in the process.

The Complete Signature of the Herb Supercritical CO2 Plus Hydroethanolic Extract Herbs contain a wide array of key compounds. Some of these valuable compounds such as resins and essentials oils are fat-soluble, while compounds such as polyphenols and polysaccharides are water-soluble. Designed by nature, these compounds work in a magical synergy. Extracting one set of compounds simply does not offer the full majesty and potential of the plant. Turmeric for example contains beneficial turmerones, which are fat-soluble as well as water-soluble flavonoids.

We support farmers who are dedicated to the principles of sustainable agriculture.

1/4 teaspoon provided

Supercritical Plus Hydroethanolic Dual Extraction

Infuse Your Beverage Enhance Your Day* Easy to Use Powder

Suggested/Recommended/Usage/Directions

These free flowing, concentrated, semi-soluble powders can be added to water, coconut water, juice, any drink, smoothie or shake. Add Smoothie Booster to Water, Smoothies or Juice. Shake & Enjoy!

Warm Herbal Infusions Make warm tea-like infusions by adding 1/8 - 1/4 of a teaspoon of powder to 16-32 oz of warm water (not boiling) and a natural sweetener of your choice such as Organic Traditions Yacon Syrup. Whisk vigorously as if making a matcha tea and enjoy. While some herbs are extremely pleasant and delicious such as Holy Basil and Cinnamon, many of these herbs such as Brahmi and Shatavari have bitter or pungent taste profiles. Use your favourite juice or smoothie for the stronger herbs and a natural sweetener of your choice such as Organic Traditions Yacon Syrup.

Suggested Use: Add 1/8 - 1/4 tsp. to 16-32 oz of water, juice, smoothies or any other recipe. Dietary supplements should not be a replacement for a varied and balanced diet, and a healthy lifestyle.

Precautions

Don’t exceed the recommended daily usage.

CAUTION: As with any dietary supplement, you should advise your healthcare practitioner of the use of the product. If you are nursing, pregnant, or considering pregnancy, you should consult your healthcare practitioner prior to using this product.

Keep out of reach of children.

Contains an oxygen absorber. Do not consume.

Storage

Store in a cool and dry place.

FDA Disclaimer Statement

These statements have not been evalutated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Certified by Ecocert ICO

Formula

Herb To Extract Ratio: Supercritical CO2 Extract – 120:1 Hydroethanolic Extract – 5:1 Composition: Supercritical CO2 Extract – 5% Hydroethanolic Extract - 91% Silicon Dioxide – 4% Key Components: Total Withanolides: 2.87% Part Used: Dried Mature Roots

Concentrated Ashwagandha Powder Water & Smoothie Booster 20 g of Fresh Ashwagandha = 1/4 tsp. of Powder

OU KOSHER

Seals/Symbols

USDA ORGANIC

OU KOSHER

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Aswagandha Smoothie Booster by Organic Traditions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Aswagandha Smoothie Booster label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Aswagandha Smoothie Booster by Organic Traditions

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.375 Gram(s) Dosage formPowder Servings per container44 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Ashwagandha (Withania somnifera) Hydroethanolic extract

Interacts with
1,372 drugs
682.5 mg per serving

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

Organic Ashwagandha (Withania somnifera) Hydroethanolic extract monograph & interactions

Organic Ashwagandha (Withania somnifera) CO2 extract

Interacts with
1,372 drugs
37.5 mg per serving

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

Organic Ashwagandha (Withania somnifera) CO2 extract monograph & interactions

Other (inactive) ingredients: Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Aswagandha Smoothie Booster by Organic Traditions Drug Interactions

Want to check YOUR meds against Aswagandha Smoothie Booster?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,372Drugs
916 Moderate 456 Minor

Ingredients driving the most interactions

organic Ashwagandha (Withania somnifera) Hydroethanolic extract 1,372

Individual Drug Interactions

The ingredients in Aswagandha Smoothie Booster interact with 1,372 drugs. Click any drug to see the details.

1 of the 2 ingredients in Aswagandha Smoothie Booster interact with drugs. Each result below shows which ingredient is responsible. organic Ashwagandha (Withania somnifera) Hydroethanolic extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Aswagandha Smoothie Booster with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Ashwagandha (Withania somnifera) Hydroethanolic extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
organic Ashwagandha (Withania somnifera) Hydroethanolic extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Aswagandha Smoothie Booster, from the product label.

Organic Traditions

See all Organic Traditions products
Name
Health Matters America Inc.
Street Address
2501 Broadway St., Unit 2
City
Cheektowaga
State
NY
ZipCode
14227
Phone Number
1-888-343-3278
Web Address
www.organictraditions.com
Pharmacist Counseling Corner

Aswagandha Smoothie Booster by Organic Traditions: Common Questions

Does Aswagandha Smoothie Booster by Organic Traditions interact with any medications?
Yes. Based on its ingredients, Aswagandha Smoothie Booster has a known interaction with 1,372 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Aswagandha Smoothie Booster contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
During pregnancy, the safety data advises against it — ashwagandha is traditionally thought to carry a miscarriage risk. While breastfeeding, there isn't enough safety information, so it's best to avoid it too. Talk to your doctor or pharmacist if you're considering it at any stage.
What are the most common side effects?
Ashwagandha can cause stomach upset, diarrhea, nausea, and vomiting, though these don't typically happen with normal doses. It may also cause drowsiness. Serious side effects are rare but include liver damage and bleeding in the brain.
How long does it take to work?
The product facts we have don't specify how long you should expect to wait before noticing effects. Talk to your pharmacist about typical timelines for your specific use.
Is this safe to use long-term?
Short-term use is generally well tolerated in healthy adults, but the long-term safety data are limited. Quality varies between products too. It's worth discussing long-term use with your pharmacist or doctor.
What's the difference between the two types of ashwagandha extract in this product?
The product contains both a hydroethanolic extract and a CO2 extract — two different ways of pulling the active compounds from the plant. Both have the same interactions and effects based on our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aswagandha Smoothie Booster label
Go deeper

The Full Monographs Behind Aswagandha Smoothie Booster’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph →
Sources

Sources & How We Checked

Aswagandha Smoothie Booster's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashwagandha 32 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
  3. Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
  4. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
  5. Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
  6. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
  7. Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
  8. Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
  9. Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
  10. Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. PubMed
  11. Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
  12. Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
  13. Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
  14. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
  15. Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020;34(5):1041-1059.
  16. Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. PubMed
  17. Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. J Clin Med 2021;1 PubMed
  18. Ireland PJ, Hardy T, Burt AD, Donnelly MC. Drug-induced hepatocellular injury due to herbal supplement ashwagandha. J R Coll Physicians Edinb. 2021;51(4):363-365. PubMed
  19. Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. PubMed
  20. Suryawanshi G, Abdallah M, Thomson M, Desai N, Chauhan A, Lim N. Ashwagandha-Associated Acute Liver Failure Requiring Liver Transplantation. Am J Ther 2023;30(1):e80-e83. PubMed
  21. Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. PubMed
  22. Ajgaonkar A, Jain M, Debnath K. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study. Cureus 2022;14(10):e30787. PubMed
  23. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  24. Lubarska M, Halasinski P, Hryhorowicz S, et al. Liver Dangers of Herbal Products: A Case Report of Ashwagandha-Induced Liver Injury. Int J Environ Res Public Health 2023;20(5):3921. PubMed
  25. Tóth M, Benedek AE, Longerich T, Seitz HK. Ashwagandha-induced acute liver injury: A case report. Clin Case Rep 2023;11(3):e7078.
  26. Bokan G, Glamocanin T, Mavija Z, et al. Herb-Induced Liver Injury by Ayurvedic Ashwagandha as Assessed for Causality by the Updated RUCAM: An Emerging Cause. Pharmaceuticals (Basel) 2023;16(8):1129. PubMed
  27. Patel PA, Sanborn E, Then R, Williams DM. Recurrent Reversible Cerebral Vasoconstriction Syndrome: A Report of Two Cases. Cureus 2023;15(8):e42992. PubMed
  28. Majeed M, Nagabhushanam K, Murali A, Vishwanathan DT, Mamidala RV, Mundkur L. A Standardized Withania somniferra (Linn.) Root Extract with Piperine Alleviates the Symptoms of Anxiety and Depression by Increasing Serotonin Levels: A Double-Blind, Randomize
  29. Philips CA, Valsan A, Theruvath AH, et al. Ashwagandha-induced liver injury-A case series from India and literature review. Hepatol Commun 2023;7(10):e0270. PubMed
  30. Hayashi M, Hamada H, Azuma SI, Hayashi K. Painless Thyroiditis by Withania somnifera (Ashwagandha). Cureus 2024;16(3):e55352. PubMed
  31. Vazirani S, Kothari A, Fujimoto J, Gomez M. Supplements Are Not a Synonym for Safe: Suspected Liver Injury From Ashwagandha. Fed Pract 2023;40(9):315-319. PubMed
  32. Patel M, Newell R, Hillier M, Ramalingam R. Herbal remedies as a potential cause of hypoadrenalism. Br J Hosp Med (Lond) 2024;85(6):1-4. PubMed

See these in context on the Ashwagandha monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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